期刊
BIOSENSORS-BASEL
卷 11, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/bios11100382
关键词
pesticide; cholinesterase; nanozyme; sensor; biosensor
资金
- Postgraduate Research and Practice Innovation Program of Jiangsu Province [KYCX21_3381, SJCX21_1673]
- Key Laboratory of Functional Molecular Solids of Ministry of Education [FMS202001]
- State Key Laboratory of Urban Water Resource and Environment [ES202122]
- National Natural Science Foundation of China [21605061]
Pesticides play a vital role in protecting crops, but their difficult-to-degrade residues pose threats to human health and the environment. Nanomaterials with enzyme-like properties, known as nanozymes, offer great potential in detecting pesticide residues and biomarkers efficiently.
To improve the output and quality of agricultural products, pesticides are globally utilized as an efficient tool to protect crops from insects. However, given that most pesticides used are difficult to decompose, they inevitably remain in agricultural products and are further enriched into food chains and ecosystems, posing great threats to human health and the environment. Thus, developing efficient methods and tools to monitor pesticide residues and related biomarkers (acetylcholinesterase and butylcholinesterase) became quite significant. With the advantages of excellent stability, tailorable catalytic performance, low cost, and easy mass production, nanomaterials with enzyme-like properties (nanozymes) are extensively utilized in fields ranging from biomedicine to environmental remediation. Especially, with the catalytic nature to offer amplified signals for highly sensitive detection, nanozymes were finding potential applications in the sensing of various analytes, including pesticides and their biomarkers. To highlight the progress in this field, here the sensing principles of pesticides and cholinesterases based on nanozyme catalysis are definitively summarized, and emerging detection methods and technologies with the participation of nanozymes are critically discussed. Importantly, typical examples are introduced to reveal the promising use of nanozymes. Also, some challenges in the field and future trends are proposed, with the hope of inspiring more efforts to advance nanozyme-involved sensors for pesticides and cholinesterases.
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