期刊
TOXICS
卷 9, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/toxics9100242
关键词
mercury (Hg); dyslipidemia; hypercholesterolemia; hyper-LDL cholesterolemia; adolescents
The study suggests that blood mercury concentration may lead to a higher prevalence of borderline hypercholesterolemia among adolescents, especially in boys. More stringent public health measures should be taken to reduce mercury exposure for dyslipidemia prevention, although further research is needed to evaluate the causal relationship.
There is limited evidence on the association between blood mercury (Hg) concentration and the risk of borderline dyslipidemia in adolescents. Here, we investigated the association between blood Hg concentration and the prevalence of borderline dyslipidemia among Korean adolescents. A total of 1559 participants (806 boys and 753 girls) aged 10-18 years who cross-sectionally enrolled in the Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2013 and 2016 were included in this study. Hg concentrations (mu g/L) in whole blood samples were measured. The geometric mean (GM) of the blood Hg concentration was 1.88 mu g/L. It showed a 63% higher prevalence of borderline hypercholesterolemia (total cholesterol (TC) 170-199 mg/dL) per unit of natural log-transformed blood Hg concentration in boys (95% CI = 1.10-2.41), but not in girls. When a categorical model was applied, the positive association with the prevalence of borderline hypercholesterolemia was also persistant in boys (OR (95% CI) for 2nd and 3rd tertiles (Hg concentration 1.532-11.761 mu g/L) vs. 1st tertile (Hg concentration 0.192-1.531 mu g/L): 1.92 (1.19-3.10)), but not in girls. This finding suggests that blood Hg concentration might result in a higher prevalence of borderline hypercholesterolemia among adolescents and more stringent public health actions should be taken for the reduction of Hg exposure to prevent dyslipidemia from early-childhood, despite the need of further study to evaluate a causal relationship between blood Hg concentration and the risk of dyslipidemia.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据