4.6 Article

The Effect of Acknowledged and Novel Anti-Rheumatic Therapies on Periodontal Tissues-A Narrative Review

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Plant Sciences

Daphnes Cortex and its licorice-processed products suppress inflammation via the TLR4/NF-κB/NLRP3 signaling pathway and regulation of the metabolic profile in the treatment of rheumatoid arthritis

Xianglong Meng et al.

Summary: This study compared the efficacy and mechanisms of action between Daphnes Cortex and its licorice-processed products in treating rheumatoid arthritis. Licorice-processed products showed better anti-inflammatory effects through the TLR4/NF-kappa B/ NLRP3 signaling pathway in RA rats and RAW264.7 cells induced by LPS.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

Article Biochemistry & Molecular Biology

Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL

Yuria Jang et al.

Summary: The mutant RANKL demonstrated the ability to inhibit osteoclastogenesis by competitively inhibiting RANKL, serving as a potential therapeutic agent for osteoporosis with fewer toxic side effects compared to traditional treatments.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Dentistry, Oral Surgery & Medicine

Specific inhibition of IL-6 receptor attenuates inflammatory bone loss in experimental periodontitis

Gustavo H. Apolinario Vieira et al.

Summary: The study showed that tocilizumab can reduce alveolar bone resorption and attachment loss caused by periodontitis by inhibiting IL-6-mediated proinflammatory activity. Additionally, it decreased inflammatory infiltrate and production of Th17-related cytokines, suggesting that modulatory therapy may be a promising approach for periodontal disease.

JOURNAL OF PERIODONTOLOGY (2021)

Article Dentistry, Oral Surgery & Medicine

Non-surgical periodontal treatment improves rheumatoid arthritis disease activity: a meta-analysis

Jia Sun et al.

Summary: The meta-analysis suggests that non-surgical periodontal treatment can significantly improve rheumatoid arthritis disease activity, particularly in terms of reducing disease activity score, joint counts, pain levels, and inflammatory markers.

CLINICAL ORAL INVESTIGATIONS (2021)

Article Rheumatology

Investigating the relationship between the severity of periodontitis and rheumatoid arthritis: a cross-sectional study

Egle Punceviciene et al.

Summary: The study revealed a high prevalence of severe PD in RA patients, significantly associated with higher RA disease activity and lower vitamin D levels in the RA-PD group, while bDMARD treatment was related to lower PD outcome parameters.

CLINICAL RHEUMATOLOGY (2021)

Article Environmental Sciences

Effect of Anti-Rheumatic Treatment on the Periodontal Condition of Rheumatoid Arthritis Patients

Menke J. de Smit et al.

Summary: The study found that treatment with methotrexate (MTX) and anti-tumor necrosis factor-alpha (anti-TNF, etanercept) had negligible influence on the periodontal condition of rheumatoid arthritis (RA) patients, but significantly improved inflammatory markers of RA.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

Article Biochemistry & Molecular Biology

Evaluation of Oxidative Stress before and after Using Laser and Photoactivation Therapy as Adjuvant of Non-Surgical Periodontal Treatment in Patients with Rheumatoid Arthritis

Maria-Alexandra Martu et al.

Summary: This study analyzed the effects of three different periodontal disease treatment possibilities on clinical periodontal indexes and oxidative stress markers in gingival crevicular fluid. The results showed that periodontal therapy improved these measurements, with laser and photodynamic therapy treatment providing additional benefits.

ANTIOXIDANTS (2021)

Article Endocrinology & Metabolism

Denosumab-related osteonecrosis of the jaw after tooth extraction and the effects of a short drug holiday in cancer patients: a multicenter retrospective study

T. Hasegawa et al.

Summary: Risk factors for denosumab-related osteonecrosis of the jaw after tooth extraction in cancer patients on oncologic doses of denosumab include pre-existing inflammation, corticosteroid therapy, periapical periodontitis, longer duration of denosumab therapy, and female sex. A short drug holiday did not protect against this complication.

OSTEOPOROSIS INTERNATIONAL (2021)

Article Rheumatology

Fatty Acids and Oxylipins in Osteoarthritis and Rheumatoid Arthritis-a Complex Field with Significant Potential for Future Treatments

Anne-Mari Mustonen et al.

Summary: OA and RA are characterized by abnormal lipid metabolism with altered FA profiles in synovial fluid and tissues. Dietary FA supplements, especially long-chain n-3 PUFA, have positive effects on joint health, while n-6 PUFA may have mixed effects. SPM analogs have potential as analgesics for arthritic pain.

CURRENT RHEUMATOLOGY REPORTS (2021)

Article Medicine, General & Internal

Impact of Different JAK Inhibitors and Methotrexate on Lymphocyte Proliferation and DNA Damage

Annika Reddig et al.

Summary: JAKis present a new strategy in rheumatoid arthritis therapy, with similar inhibitory effects on lymphocyte proliferation but potential detrimental effects on cell viability and DNA damage repair at high doses. The study provides insights into the immunomodulatory effects of different JAKis and their impact on PBMCs.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Biochemistry & Molecular Biology

Selective Antimicrobial Therapies for Periodontitis: Win the Battle and the War

Mahmoud Elashiry et al.

Summary: Traditional antimicrobial therapies for periodontitis mainly focus on non-selective and direct approaches, such as SRP. While effective in the short term, these therapies may lead to recurrence of the disease. Therefore, more attention is needed on the long-term consequences of chronic antibiotic use and their potential impact.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Dentistry, Oral Surgery & Medicine

Global, regional, and national burden of severe periodontitis, 1990-2019: An analysis of the Global Burden of Disease Study 2019

Meng Xuan Chen et al.

Summary: This study reveals a global increasing trend in the prevalence of severe periodontitis from 1990 to 2019, particularly in less developed countries and regions. Global population growth is identified as the main factor contributing to the rise in severe periodontitis cases.

JOURNAL OF CLINICAL PERIODONTOLOGY (2021)

Review Medicine, General & Internal

Mesenchymal stem/stromal cell-based therapy for the treatment of rheumatoid arthritis: An update on preclinical studies

Mercedes Lopez-Santalla et al.

Summary: Research analyzed key aspects and new approaches of using mesenchymal stem cell therapy for rheumatoid arthritis, showing promise for improving treatment efficacy.

EBIOMEDICINE (2021)

Review Pharmacology & Pharmacy

Periodontitis and Systemic Disorder-An Overview of Relation and Novel Treatment Modalities

Pooja Jain et al.

Summary: Periodontitis, a common oral disease, has been found to impact systemic disorders such as cardiovascular diseases and diabetes. Understanding the pathogenesis of periodontal infection is crucial in preventing systemic complications, leading to the importance of early and appropriate treatment.

PHARMACEUTICS (2021)

Review Biochemistry & Molecular Biology

Targeting Toll-like Receptor (TLR) Pathways in Inflammatory Arthritis: Two Better Than One?

Sandra Santos-Sierra

Summary: Inflammatory arthritis is a group of diseases caused by dysregulated immune system activity, and various medications are used to control the excessive immune response. However, drug resistances, flare-reactions, and adverse effects to current therapies are common in affected patients.

BIOMOLECULES (2021)

Article Rheumatology

In vitro evaluation of disease-modifying antirheumatic drugs against rheumatoid arthritis associated pathogens of the oral microflora

Manuel Kussmann et al.

Summary: The study found that aurothiomalate, sulfasalazine, and methotrexate showed antimicrobial activity against a broad spectrum of RA-associated pathogens in the oral microbiota. Among them, methotrexate exhibited relevant antimicrobial activity against certain bacteria, while aurothiomalate and sulfasalazine were active only at high supratherapeutic concentrations. The findings suggest a potential link between antimicrobially active antirheumatic drugs and their therapeutic effects in treating RA.

RMD OPEN (2021)

Article Medicine, General & Internal

The Effects of Prednisone/Ketoprofen Administration in Association with Amoxicillin Clavulanate Following Periodontal Surgical Therapy in Patients with Severe Chronic Periodontitis

Lidia Sfetcu et al.

Summary: The study showed that both ketoprofen and prednisone combined with antibiotics and periodontal surgery were effective in improving inflammatory periodontal parameters. Prednisone treatment alone led to a significant decrease in salivary cortisol levels in patients with severe chronic periodontitis.

MEDICINA-LITHUANIA (2021)

Review Immunology

Transformation of fibroblast-like synoviocytes in rheumatoid arthritis; from a friend to foe

Mohammad Javad Mousavi et al.

Summary: Rheumatoid arthritis (RA) is characterized by swelling and progressive destruction of articular cartilage, with fibroblast-like synoviocytes (FLSs) playing a crucial role in disease progression. FLSs exhibit invasive behavior similar to tumor conditions, leading to recruitment of other immune cells and eventually pannus formation. The cancer-like phenotype of RA FLSs arises from metabolic changes and genetic abnormalities, with implications for targeted treatment strategies.

AUTOIMMUNITY HIGHLIGHTS (2021)

Article Immunology

ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome

Xiwen Dong et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2020)

Article Allergy

Resolvins: Emerging Players in Autoimmune and Inflammatory Diseases

Fereshte Abdolmaleki et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2020)

Article Rheumatology

Treatment strategies are more important than drugs in the management of rheumatoid arthritis

Alexandros A. Drosos et al.

CLINICAL RHEUMATOLOGY (2020)

Review Dentistry, Oral Surgery & Medicine

Periodontal therapeutics: Current host-modulation agents and future directions

Lorne M. Golub et al.

PERIODONTOLOGY 2000 (2020)

Review Pharmacology & Pharmacy

The past, present and future perspectives of matrix metalloproteinase inhibitors

Kang A. Li et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Review Cell Biology

Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis

Qinghua Fang et al.

MEDIATORS OF INFLAMMATION (2020)

Review Cell Biology

Structure and Function of Human Matrix Metalloproteinases

Helena Laronha et al.

Review Pharmacology & Pharmacy

New insight into unexpected bone formation by denosumab

Lipeng Wang et al.

DRUG DISCOVERY TODAY (2020)

Review Environmental Sciences

The Role of Matrix Metalloproteinases in Periodontal Disease

Vittorio Checchi et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

Article Dentistry, Oral Surgery & Medicine

Cellular expression of DNA damage/repair and reactive oxygen/nitrogen species in human periodontitis and peri-implantitis lesions

Carlotta Dionigi et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2020)

Review Immunology

JAK Inhibitors in Rheumatoid Arthritis: An Evidence-Based Review on the Emerging Clinical Data

Robert Harrington et al.

JOURNAL OF INFLAMMATION RESEARCH (2020)

Review Medicine, General & Internal

Cytokines and Their Genetic Polymorphisms Related to Periodontal Disease

Malgorzata Kozak et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Immunology

Toward the Characterization of Human Pro-Resolving Macrophages?

Philippe Saas et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Endocrinology & Metabolism

Periodontitis and Rheumatoid Arthritis: the Common Thread

Namrata S. Jajoo et al.

CLINICAL REVIEWS IN BONE AND MINERAL METABOLISM (2020)

Review Biochemistry & Molecular Biology

Th17 Cells and the IL-23/IL-17 Axis in the Pathogenesis of Periodontitis and Immune-Mediated Inflammatory Diseases

Kuebra Bunte et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Biochemistry & Molecular Biology

Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Biological Interactions

Rafael Scaf de Molon et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Dentistry, Oral Surgery & Medicine

Periodontal Medicine: 100 Years of Progress

J. D. Beck et al.

JOURNAL OF DENTAL RESEARCH (2019)

Article Medicine, General & Internal

Rheumatoid Arthritis Treatment. A Back to the Drawing Board Project or High Expectations for Low Unmet Needs?

Alexandros A. Drosos et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Review Cell Biology

Strategies toward rheumatoid arthritis therapy; the old and the new

Mojtaba Abbasi et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Review Rheumatology

Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis

Zhu Chen et al.

NATURE REVIEWS RHEUMATOLOGY (2019)

Article Orthopedics

Zoledronic acid ameliorates the effects of secondary osteoporosis in rheumatoid arthritis patients

Jun Xie et al.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2019)

Review Dentistry, Oral Surgery & Medicine

Host modulation therapy with anti-inflammatory agents

Philip M. Preshaw

PERIODONTOLOGY 2000 (2018)

Article Pharmacology & Pharmacy

Anti-mouse RANKL Antibodies Inhibit Alveolar Bone Destruction in Periodontitis Model Mice

Miku Kuritani et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2018)

Review Geriatrics & Gerontology

DNA damage, metabolism and aging in pro-inflammatory T cells Rheumatoid arthritis as a model system

Yinyin Li et al.

EXPERIMENTAL GERONTOLOGY (2018)

Review Medicine, Research & Experimental

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

Charles N. Serhan et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Dentistry, Oral Surgery & Medicine

Denosumab-related osteonecrosis of the jaw following non-surgical periodontal therapy: A case report

Marcio Diniz-Freitas et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2018)

Article Dentistry, Oral Surgery & Medicine

Osteonecrosis of the jaw in patients treated with denosumab: A multicenter case series

Suad Aljohani et al.

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY (2018)

Review Multidisciplinary Sciences

Gene therapy comes of age

Cynthia E. Dunbar et al.

SCIENCE (2018)

Review Pharmacology & Pharmacy

MMP-Responsive 'Smart' Drug Delivery and Tumor Targeting

Qing Yao et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2018)

Article Immunology

NLRP3 inflammasome activation contributes to the pathogenesis of rheumatoid arthritis

C. Guo et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2018)

Review Dentistry, Oral Surgery & Medicine

Lifestyle and periodontitis: The emergence of personalized periodontics

P. Mark Bartold

PERIODONTOLOGY 2000 (2018)

Review Medicine, General & Internal

Diagnosis and Management of Rheumatoid Arthritis A Review

Daniel Aletaha et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

Review Microbiology

Epigenetic regulation in bacterial infections: targeting histone deacetylases

Aleksander M. Grabiec et al.

CRITICAL REVIEWS IN MICROBIOLOGY (2018)

Article Allergy

Biologic Therapies for Autoimmune and Connective Tissue Diseases

Rachel M. Wolfe et al.

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA (2017)

Review Biochemistry & Molecular Biology

Matrix Metalloproteinase Gene Activation Resulting from Disordred Epigenetic Mechanisms in Rheumatoid Arthritis

Yasuto Araki et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Biochemistry & Molecular Biology

Matrix Metalloproteinases as Regulators of Periodontal Inflammation

Cavalla Franco et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Rheumatology

Rheumatoid arthritis and periodontal disease: What are the similarities and differences?

Rongbin Li et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2017)

Article Medicine, General & Internal

Pathogenetic insights from the treatment of rheumatoid arthritis

Iain B. McInnes et al.

LANCET (2017)

Article Medicine, General & Internal

Novel treatment strategies in rheumatoid arthritis

Gerd R. Burmester et al.

LANCET (2017)

Review Biochemistry & Molecular Biology

Pro-resolving mediators in the regulation of periodontal disease

Thomas E. Van Dyke

MOLECULAR ASPECTS OF MEDICINE (2017)

Article Food Science & Technology

Targeting the epigenome: Screening bioactive compounds that regulate histone deacetylase activity

Luis D. Godoy et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2017)

Review Rheumatology

Influence of periodontal treatment on rheumatoid arthritis: a systematic review and meta-analysis

Debora Cerqueira Calderaro et al.

REVISTA BRASILEIRA DE REUMATOLOGIA (2017)

Review Immunology

Emerging Concepts in the Resolution of Periodontal Inflammation: A Role for Resolvin E1

Maria G. Balta et al.

FRONTIERS IN IMMUNOLOGY (2017)

Review Medicine, Research & Experimental

Rheumatoid arthritis: Recent advances on its etiology, role of cytokines and pharmacotherapy

Javaid Alam et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Review Dentistry, Oral Surgery & Medicine

Azithromycin as an adjunct to non-surgical periodontal therapy: a systematic review

V. J. O'Rourke

AUSTRALIAN DENTAL JOURNAL (2017)

Review Endocrinology & Metabolism

Histone deacetylases (HDAC) in physiological and pathological bone remodelling

M. D. Cantley et al.

Review Dentistry, Oral Surgery & Medicine

Non-antibacterial tetracycline formulations: host-modulators in the treatment of periodontitis and relevant systemic diseases

Lorne M. Golub et al.

INTERNATIONAL DENTAL JOURNAL (2016)

Review Dentistry, Oral Surgery & Medicine

Clinical research activity in periodontal medicine: a systematic mapping of trial registers

Paul Monsarrat et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2016)

Article Biochemistry & Molecular Biology

Specialised pro-resolving mediators of inflammation in inflammatory arthritis

Anne E. Barden et al.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2016)

Article Biochemistry & Molecular Biology

Glucocorticoids in Patients with Rheumatic Diseases: Friends or Enemies of Bone?

Fedra Ciccarelli et al.

CURRENT MEDICINAL CHEMISTRY (2015)

Article Dentistry, Oral Surgery & Medicine

Tissue engineering for bone regeneration and osseointegration in the oral cavity

Sophia P. Pilipchuk et al.

DENTAL MATERIALS (2015)

Article Biochemistry & Molecular Biology

Aberrant histone acetylation contributes to elevated interleukin-6 production in rheumatoid arthritis synovial fibroblasts

Takuma Tsuzuki Wada et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Rheumatology

Periodontitis and Porphyromonas gingivalis in Patients With Rheumatoid Arthritis

Ted R. Mikuls et al.

ARTHRITIS & RHEUMATOLOGY (2014)

Article Dentistry, Oral Surgery & Medicine

Periodontal Condition of Patients With Autoimnnune Diseases and the Effect of Anti-Tumor Necrosis Factor-α Therapy

Yaniv Mayer et al.

JOURNAL OF PERIODONTOLOGY (2013)

Review Rheumatology

Use of NSAIDs in treating patients with arthritis

Leslie J. Crofford

ARTHRITIS RESEARCH & THERAPY (2013)

Article Rheumatology

Persistent Periodontal Disease Hampers Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis

Cynthia Savioli et al.

JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2012)

Review Rheumatology

The multiple facets of glucocorticoid action in rheumatoid arthritis

Ulrike Baschant et al.

NATURE REVIEWS RHEUMATOLOGY (2012)

Article Dentistry, Oral Surgery & Medicine

Adjunctive Treatment of Chronic Periodontitis With Daily Dietary Supplementation With Omega-3 Fatty Acids and Low-Dose Aspirin

Hesham EI-Sharkawy et al.

JOURNAL OF PERIODONTOLOGY (2010)

Article Rheumatology

A Prospective Study of Periodontal Disease and Risk of Rheumatoid Arthritis

Elizabeth V. Arkema et al.

JOURNAL OF RHEUMATOLOGY (2010)

Article Dentistry, Oral Surgery & Medicine

Anti-Tumor Necrosis Factor-Alpha Therapy and Periodontal Parameters in Patients With Rheumatoid Arthritis

Yaniv Mayer et al.

JOURNAL OF PERIODONTOLOGY (2009)

Article Multidisciplinary Sciences

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

Matthew Spite et al.

NATURE (2009)

Review Medicine, General & Internal

New therapies for treatment of rheumatoid arthritis

Josef S. Smolen et al.

LANCET (2007)

Article Biochemistry & Molecular Biology

RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis

H. Hasturk et al.

FASEB JOURNAL (2006)

Article Dentistry, Oral Surgery & Medicine

Oral health in patients on inhaled corticosteroid treatment

N Komerik et al.

ORAL DISEASES (2005)

Article Dentistry, Oral Surgery & Medicine

Relationship between rheumatoid arthritis and periodontitis

FB Mercado et al.

JOURNAL OF PERIODONTOLOGY (2001)