期刊
JOURNAL OF FUNGI
卷 8, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/jof8010028
关键词
metabolomics; endophytic fungi; bioactive metabolites; nuclear magnetic resonance; liquid chromatography-high-resolution mass spectrometry; extraction; analytical tool; systems biology
资金
- Ministry of Higher Education Malaysia [FRGS/1/2018/STG01/USM/02/3]
Endophytic fungi are microorganisms that colonize living plants' tissues without causing harm. They are a natural source of bioactive metabolites with diverse pharmacological functions. Metabolomics studies of endophytic fungi are relatively unexplored.
Endophytic fungi are microorganisms that colonize living plants' tissues without causing any harm. They are known as a natural source of bioactive metabolites with diverse pharmacological functions. Many structurally different chemical metabolites were isolated from endophytic fungi. Recently, the increasing trends in human health problems and diseases have escalated the search for bioactive metabolites from endophytic fungi. The conventional bioassay-guided study is known as laborious due to chemical complexity. Thus, metabolomics studies have attracted extensive research interest owing to their potential in dealing with a vast number of metabolites. Metabolomics coupled with advanced analytical tools provides a comprehensive insight into systems biology. Despite its wide scientific attention, endophytic fungi metabolomics are relatively unexploited. This review highlights the recent developments in metabolomics studies of endophytic fungi in obtaining the global metabolites picture.
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