期刊
BIOMEDICINES
卷 9, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/biomedicines9101341
关键词
Parkinson's disease; astrocyte; dopamine neuron; cell treatment
资金
- Curemos el Parkinson
- Center for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain [PI2014/06]
Currently, there is no efficient treatment to prevent the evolution of Parkinson's disease, which is generated by the concurrent activity of multiple factors, posing a serious obstacle for the development of etio-pathogenic treatments. Astrocytes may play a key role in controlling the main causes of PD and promoting their neuroprotection activity to prevent the onset and progression of this basal ganglia disorder.
At present, there is no efficient treatment to prevent the evolution of Parkinson's disease (PD). PD is generated by the concurrent activity of multiple factors, which is a serious obstacle for the development of etio-pathogenic treatments. Astrocytes may act on most factors involved in PD and the promotion of their neuroprotection activity may be particularly suitable to prevent the onset and progression of this basal ganglia (BG) disorder. The main causes proposed for PD, the ability of astrocytes to control these causes, and the procedures that can be used to promote the neuroprotective action of astrocytes will be commented upon, here.
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