4.7 Article

A Hyaluronic Acid Demilune Scaffold and Polypyrrole-Coated Fibers Carrying Embedded Human Neural Precursor Cells and Curcumin for Surface Capping of Spinal Cord Injuries

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Clinical Neurology

The Preventive Effect of Curcumin on the Experimental Rat Epidural Fibrosis Model

Cem Demirel et al.

Summary: The study demonstrated that systemic administration of curcumin significantly reduced inflammation, foreign body reaction, granulation tissue formation, medulla spinalis retraction, and epidural fibrosis formation in a rat laminectomy model. Different doses of curcumin did not show significant differences in their effects on these outcomes.

WORLD NEUROSURGERY (2021)

Article Materials Science, Multidisciplinary

Solid Polymer Electrolytes Based on Polylactic Acid Nanofiber Mats Coated with Polypyrrole

Fernando Gisbert Roca et al.

Summary: The study explores electroconductive nanofiber membranes made from polylactic acid coated with polypyrrole, showing high conductivity values and thermal stability below 140 degrees Celsius, making them suitable for various applications such as batteries, sensors, and polymer electrolyte membrane fuel cells.

MACROMOLECULAR MATERIALS AND ENGINEERING (2021)

Article Neurosciences

Improvement of Rat Spinal Cord Injury Following Lentiviral Vector-Transduced Neural Stem/Progenitor Cells Derived from Human Epileptic Brain Tissue Transplantation with a Self-assembling Peptide Scaffold

Sara Abdolahi et al.

Summary: Research has shown that the co-application of hNS/PCs and PM after SCI can enhance cell survival and differentiation, reduce lesion volume, and improve neurological function. Additionally, transplanted hNS/PCs seeded in PM demonstrate higher migration and differentiation abilities.

MOLECULAR NEUROBIOLOGY (2021)

Article Biochemistry & Molecular Biology

BDNF-Gene Transfected Schwann Cell-Assisted Axonal Extension and Sprouting on New PLA-PPy Microfiber Substrates

Fernando Gisbert Roca et al.

Summary: The study investigates the impact of enhancing BDNF production through electroporated Schwann cells on axonal extension in a coculture system, with potential applications in treating nervous system injuries. The gene-transfected SCs demonstrate a significant increase in BDNF secretion, leading to accelerated and guided axonal growth compared to nonelectroporated SCs. The use of electrotransfected SCs on highly aligned microfiber substrates shows promise in promoting axonal extension and sprouting.

MACROMOLECULAR BIOSCIENCE (2021)

Article Engineering, Biomedical

A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury

E. Giraldo et al.

Summary: Research shows that improving the stability of fasudil by conjugating it with polymers in a bioresponsive manner can enhance its therapeutic potential in treating spinal cord injuries. The conjugate PGA-SS-F, designed based on the conditions after SCI, significantly promotes neurite elongation and axon growth, reduces early apoptosis, and enhances cell engraftment in a rat model of SCI. This synergistic therapeutic approach may offer a promising clinical strategy for SCI treatment.

BIOMATERIALS (2021)

Article Biochemistry & Molecular Biology

Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment

Pablo Bonilla et al.

Summary: The combination of PA-C with stem cell transplantation has been shown to protect neural stem cells in vitro, significantly reduce scar formation, promote preservation of neurons and axons, and inhibit inflammatory response in microglia.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Engineering, Biomedical

Engineered axon tracts within tubular biohybrid scaffolds

Laura Rodriguez Doblado et al.

Summary: This study utilizes a cells-biomaterials strategy to promote axon regeneration by combining a HA conduit filled with PLA fibers with pre-cultured SCs. The biohybrid mimics the directional features of axonal pathways in the nervous system, providing potential for strategies in the regeneration of axonal tracts.

JOURNAL OF NEURAL ENGINEERING (2021)

Article Cell & Tissue Engineering

A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair generating improved genetically stable human induced pluripotent stem cells

Ana Belen Alvarez-Palomo et al.

Summary: The study demonstrates that utilizing synthetic mRNA transfection of CYCLIN D1 during reprogramming repairs DNA and significantly improves the genetic stability of human iPSC. This method reduces various genetic instabilities, decreases DNA damage, promotes correct protein expression, and reduces single-nucleotide polymorphism changes per chromosome.

STEM CELLS (2021)

Article Cell & Tissue Engineering

Biohybrids for spinal cord injury repair

Cristina Martinez-Ramos et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2019)

Article Biotechnology & Applied Microbiology

Curcumin Induces Neural Differentiation of Human Pluripotent Embryonal Carcinoma Cells through the Activation of Autophagy

Nudjanad Heebkaew et al.

BIOMED RESEARCH INTERNATIONAL (2019)

Article Biochemistry & Molecular Biology

Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury

David Oliveira Dias et al.

Article Engineering, Environmental

Biocompatibility, biodegradation and excretion of polylactic acid (PLA) in medical implants and theranostic systems

Dana da Silva et al.

CHEMICAL ENGINEERING JOURNAL (2018)

Article Biochemical Research Methods

Generation and post-injury integration of human spinal cord neural stem cells

Hiromi Kumamaru et al.

NATURE METHODS (2018)

Article Neurosciences

Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine

Yang Fan et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2018)

Article Chemistry, Multidisciplinary

Curcumin administration suppresses collagen synthesis in the hearts of rats with experimental diabetes

Shuang Guo et al.

ACTA PHARMACOLOGICA SINICA (2018)

Review Neurosciences

Cell transplantation therapy for spinal cord injury

Peggy Assinck et al.

NATURE NEUROSCIENCE (2017)

Article Nanoscience & Nanotechnology

Functional Self-Assembling Peptide Nanofiber Hydrogels Designed for Nerve Degeneration

Yuqiao Sun et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

Review Pharmacology & Pharmacy

Biocompatibility and safety of PLA and its copolymers

Yuval Ramot et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Article Clinical Neurology

Hyaluronic acid scaffold has a neuroprotective effect in hemisection spinal cord injury

Sergiy V. Kushchayev et al.

JOURNAL OF NEUROSURGERY-SPINE (2016)

Review Cell & Tissue Engineering

Concise Review: Bridging the Gap: Novel Neuroregenerative and Neuroprotective Strategies in Spinal Cord Injury

Christopher S. Ahuja et al.

STEM CELLS TRANSLATIONAL MEDICINE (2016)

Article Engineering, Biomedical

Functional recovery in spinal cord injured rats using polypyrrole/iodine implants and treadmill training

Laura Alvarez-Mejia et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2015)

Review Medicine, Research & Experimental

Application of encapsulation technology in stem cell therapy

Maryam Hashemi et al.

LIFE SCIENCES (2015)

Article Cell & Tissue Engineering

Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner

Alexander Birbrair et al.

STEM CELL RESEARCH & THERAPY (2014)

Article Physiology

Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury

Monica R. Smith et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2010)

Article Engineering, Biomedical

Effect of 3D-scaffold formation on differentiation and survival in human neural progenitor cells

Stefanie Ortinau et al.

BIOMEDICAL ENGINEERING ONLINE (2010)

Article Neurosciences

Compatibility of human fetal neural stem cells with hydrogel biomaterials in vitro

Jason R. Thonhoff et al.

BRAIN RESEARCH (2008)

Article Engineering, Biomedical

Substrate curvature influences the direction of nerve outgrowth

RM Smeal et al.

ANNALS OF BIOMEDICAL ENGINEERING (2005)

Article Engineering, Biomedical

Evaluation of biocompatibility of polypyrrole in vitro and in vivo

XD Wang et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2004)

Review Cell Biology

Get a ligand, get a life: integrins, signaling and cell survival

DG Stupack et al.

JOURNAL OF CELL SCIENCE (2002)

Review Chemistry, Applied

Preparation, properties and applications of polypyrroles

LX Wang et al.

REACTIVE & FUNCTIONAL POLYMERS (2001)

Review Chemistry, Multidisciplinary

The mechanisms of pyrrole electropolymerization

S Sadki et al.

CHEMICAL SOCIETY REVIEWS (2000)