Plant-Derived Substances with Antibacterial, Antioxidant, and Flavoring Potential to Formulate Oral Health Care Products

Bacterial diseases and reactive oxygen species can cause dental caries and oral cancer. Therefore, the present review analyzes and discusses the antibacterial and antioxidant properties of synthetic and plant-derived substances and their current and future patents to formulate dental products. The reviewed evidence indicates that chlorhexidine, fluorides, and hydrogen peroxide have adverse effects on the sensory acceptability of oral care products. As an alternative, plant-derived substances have antimicrobial and antioxidant properties that can be used in their formulation. Also, adding plant metabolites favors the sensory acceptability of dental products compared with synthetic compounds. Therefore, plant-derived substances have antibacterial, antioxidant, and flavoring activity with the potential to be used in the formulation of toothpaste, mouth rinses, dentures cleansers-fixatives, and saliva substitutes.

Automated summary

The review discusses the antibacterial and antioxidant properties of synthetic and plant-derived substances for formulating dental products. Synthetic compounds like chlorhexidine and hydrogen peroxide have negative effects on sensory acceptability, while plant metabolites offer a better alternative with antimicrobial and antioxidant properties. Plant-derived substances have potential for use in toothpaste, mouth rinses, denture cleansers-fixatives, and saliva substitutes.