相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma
Qianfei Zhang et al.
CANCER DISCOVERY (2021)
Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma
Michael D. Jain et al.
BLOOD (2021)
Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma
T. K. Choueiri et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response
Jeong A. Park et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)
Gr-MDSC-linked asset as a potential immune biomarker in pretreated NSCLC receiving nivolumab as second-line therapy
A. Passaro et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2020)
Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor microenvironment
Suzanne Ostrand-Rosenberg et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2020)
Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice
Lingyu Wei et al.
ONCOGENE (2020)
Microsomal prostaglandin E synthase-1 promotes lung metastasis via SDF-1/CXCR4-mediated recruitment of CD11b(+)Gr1(+)MDSCs from bone marrow
Ryo Takahashi et al.
BIOMEDICINE & PHARMACOTHERAPY (2020)
PAR2 deficiency enhances myeloid cell-mediated immunosuppression and promotes colitis-associated tumorigenesis
Ziliang Ke et al.
CANCER LETTERS (2020)
IL6/STAT3 Signaling Orchestrates Premetastatic Niche Formation and Immunosuppressive Traits in Lung
Bo Jing et al.
CANCER RESEARCH (2020)
Myeloid-derived suppressor cells-new and exciting players in lung cancer
Zhenzhen Yang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Therapeutic Targeting of Vasculature in the Premetastatic and Metastatic Niches Reduces Lung Metastasis
Shanawaz M. Ghouse et al.
JOURNAL OF IMMUNOLOGY (2020)
Chemokines and their receptors promoting the recruitment of myeloid-derived suppressor cells into the tumor
Bao-Hua Li et al.
MOLECULAR IMMUNOLOGY (2020)
Epigenetic therapy inhibits metastases by disrupting premetastatic niches
Zhihao Lu et al.
NATURE (2020)
CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas
Joseph A. Flores-Toro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Activated Hepatic Stellate Cells (HSCs) Exert Immunosuppressive Effects in Hepatocellular Carcinoma by Producing Complement C3
Yaping Xu et al.
ONCOTARGETS AND THERAPY (2020)
Selective targeting of different populations of myeloid-derived suppressor cells by histone deacetylase inhibitors
Ayumi Hashimoto et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2020)
Myeloid-derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2/p-STAT3 signalling pathway
Xiaofeng Li et al.
FEBS JOURNAL (2020)
Valproic acid attenuates CCR2-dependent tumor infiltration of monocytic myeloid-derived suppressor cells, limiting tumor progression
Zhiqi Xie et al.
ONCOIMMUNOLOGY (2020)
Porphyromonas gingivalis Promotes Oral Squamous Cell Carcinoma Progression in an Immune Microenvironment
L. Wen et al.
JOURNAL OF DENTAL RESEARCH (2020)
1α, 25 Dihydroxyvitamin D (1,25(OH)2D) inhibits the T cell suppressive function of myeloid derived suppressor cells (MDSC)
J. C. Fleet et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2020)
Lung resided monocytic myeloid-derived suppressor cells contribute to premetastatic niche formation by enhancing MMP-9 expression
Juechao Zhang et al.
MOLECULAR AND CELLULAR PROBES (2020)
PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
Tong Wang et al.
ONCOGENE (2020)
The New Era of Cancer Immunotherapy: Targeting Myeloid-Derived Suppressor Cells to Overcome Immune Evasion
Paola De Cicco et al.
FRONTIERS IN IMMUNOLOGY (2020)
Circulating Myeloid-derived Suppressor Cells Facilitate Invasion of Thyroid Cancer Cells by Repressing miR-486-3p
Li Chen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)
Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer
Je-In Youn et al.
SCIENTIFIC REPORTS (2020)
PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates
Yago Pico de Coana et al.
ONCOIMMUNOLOGY (2020)
Myeloid-Derived Suppressor Cells Recruited by Chemokine (C-C Motif) Ligand 3 Promote the Progression of Breast Cancer via Phosphoinositide 3-Kinase-Protein Kinase B-Mammalian Target of Rapamycin Signaling
Anqi Luo et al.
JOURNAL OF BREAST CANCER (2020)
How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions
Annika M. Bruger et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells
Prajna Guha et al.
ONCOGENE (2019)
KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer
Wenting Liao et al.
CANCER CELL (2019)
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
Luca Cassetta et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2
Zhi-Wei Li et al.
GASTROENTEROLOGY (2019)
Early-Life Microbiota Exposure Restricts Myeloid-Derived Suppressor Cell-Driven Colonic Tumorigenesis
Akihito Harusato et al.
CANCER IMMUNOLOGY RESEARCH (2019)
Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity
Juan J. Miret et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Vasohibin-2 plays an essential role in metastasis of pancreatic ductal adenocarcinoma
Rie Iida-Norita et al.
CANCER SCIENCE (2019)
Receptor-Interacting Protein Kinase 3 Deficiency Recruits Myeloid-Derived Suppressor Cells to Hepatocellular Carcinoma Through the Chemokine (C-X-C Motif) Ligand 1-Chemokine (C-X-C Motif) Receptor 2 Axis
Yi-Ming Li et al.
HEPATOLOGY (2019)
PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling
Marc L. Sprouse et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation
Lisha Ai et al.
MOLECULAR CANCER (2019)
RS 504393 inhibits M-MDSCs recruiting in immune microenvironment of bladder cancer after gemcitabine treatment
Xing-Yu Mu et al.
MOLECULAR IMMUNOLOGY (2019)
Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
Ivan Perrot et al.
CELL REPORTS (2019)
Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Jie Deng et al.
CANCER IMMUNOLOGY RESEARCH (2019)
Melanoma Extracellular Vesicles Generate Immunosuppressive Myeloid Cells by Upregulating PD-L1 via TLR4 Signaling
Viktor Fleming et al.
CANCER RESEARCH (2019)
Upregulation of IL-6 in CUL4B-deficient myeloid-derived suppressive cells increases the aggressiveness of cancer cells
Zhiliang Xu et al.
ONCOGENE (2019)
CXCR4 antagonism in combination with IDO1 inhibition weakens immune suppression and inhibits tumor growth in mouse breast cancer bone metastases
Jian Zhang et al.
ONCOTARGETS AND THERAPY (2019)
Granulocytic Myeloid-Derived Suppressor Cells Promote the Stemness of Colorectal Cancer Cells through Exosomal S100A9
Yungang Wang et al.
ADVANCED SCIENCE (2019)
SPARC Is a New Myeloid-Derived Suppressor Cell Marker Licensing Suppressive Activities
Sabina Sangaletti et al.
FRONTIERS IN IMMUNOLOGY (2019)
Perforin and Granzyme B Expressed by Murine Myeloid-Derived Suppressor Cells: A Study on Their Role in Outgrowth of Cancer Cells
Ines Dufait et al.
CANCERS (2019)
Tumor-induced peripheral immunosuppression promotes brain metastasis in patients with non-small cell lung cancer
Yuping D. Li et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study
Georgina Long et al.
LANCET ONCOLOGY (2019)
The mechanism of the premetastatic niche facilitating colorectal cancer liver metastasis generated from myeloid-derived suppressor cells induced by the S1PR1-STAT3 signaling pathway
Qi Lin et al.
CELL DEATH & DISEASE (2019)
Myeloid-Derived Suppressive Cells Promote B cell-Mediated Immunosuppression via Transfer of PD-L1 in Glioblastoma
Catalina Lee-Chang et al.
CANCER IMMUNOLOGY RESEARCH (2019)
S100A9 Regulates MDSCs-Mediated Immune Suppression via the RAGE and TLR4 Signaling Pathways in Colorectal Carcinoma
Mao Huang et al.
FRONTIERS IN IMMUNOLOGY (2019)
Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3
Rosalinda Trovato et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Cancer-Derived VEGF-C Increases Chemokine Production in Lymphatic Endothelial Cells to Promote CXCR2-Dependent Cancer Invasion and MDSC Recruitment
Jing-Yi Chen et al.
CANCERS (2019)
Myeloid-Derived Suppressor Cells Promote Metastasis in Breast Cancer After the Stress of Operative Removal of the Primary Cancer
Xuelei Ma et al.
FRONTIERS IN ONCOLOGY (2019)
Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma
Yaping Xu et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
SDF-1/CXCR4 axis facilitates myeloid-derived suppressor cells accumulation in osteosarcoma microenvironment and blunts the response to anti-PD-1 therapy
Kuo Jiang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
Cabozantinib in Combination with Immunotherapy for Advanced Renal Cell Carcinoma and Urothelial Carcinoma: Rationale and Clinical Evidence
Paulo Bergerot et al.
MOLECULAR CANCER THERAPEUTICS (2019)
Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells
Marion Dajon et al.
ONCOIMMUNOLOGY (2019)
Tim-3/galectin-9 pathway and mMDSC control primary and secondary resistances to PD-1 blockade in lung cancer patients
Emeric Limagne et al.
ONCOIMMUNOLOGY (2019)
Cancer-educated mesenchymal stem cells promote the survival of cancer cells at primary and distant metastatic sites via the expansion of bone marrow-derived-PMN-MDSCs
Buqing Sai et al.
CELL DEATH & DISEASE (2019)
CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB
Ya-Ling Hsu et al.
BREAST CANCER RESEARCH (2019)
Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs
Momir Bosiljcic et al.
BREAST CANCER RESEARCH (2019)
The potential predictive value of circulating immune cell ratio and tumor marker in atezolizumab treated advanced non-small cell lung cancer patients
Minglei Zhuo et al.
CANCER BIOMARKERS (2018)
Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer
Lifeng Li et al.
CANCER RESEARCH (2018)
Blockade of Myeloid-Derived Suppressor Cell Expansion with All-Trans Retinoic Acid Increases the Efficacy of Antiangiogenic Therapy
Raimund Bauer et al.
CANCER RESEARCH (2018)
A RIPK3-PGE(2) Circuit Mediates Myeloid-Derived Suppressor Cell-Potentiated Colorectal Carcinogenesis
Guifang Yan et al.
CANCER RESEARCH (2018)
The Highly Metastatic Nature of Uterine Cervical/Endometrial Cancer Displaying Tumor-Related Leukocytosis: Clinical and Preclinical Investigations
Tomoyuki Sasano et al.
CLINICAL CANCER RESEARCH (2018)
Clinical Relevance and Suppressive Capacity of Human Myeloid-Derived Suppressor Cell Subsets
Stephan Lang et al.
CLINICAL CANCER RESEARCH (2018)
Characterization of Multiple Cytokine Combinations and TGF-beta on Differentiation and Functions of Myeloid-Derived Suppressor Cells
Cho-Rong Lee et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Myeloid-Derived Suppressor Cells Impair B Cell Responses in Lung Cancer through IL-7 and STAT5
Yong Wang et al.
JOURNAL OF IMMUNOLOGY (2018)
Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
Mana Taki et al.
NATURE COMMUNICATIONS (2018)
A novel MDSC-induced PD-1(-)PD-L1(+) B-cell subset in breast tumor microenvironment possesses immuno-suppressive properties
Meng Shen et al.
ONCOIMMUNOLOGY (2018)
The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells
Tingting Wang et al.
IMMUNITY (2018)
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy
Padmini Jayaraman et al.
ONCOIMMUNOLOGY (2018)
ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer
Sushil Kumar et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy
Priyamvada Jayaprakash et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis
Mohammed L. Ibrahim et al.
CELL REPORTS (2018)
Presence of Infected Gr-1intCD11bhiCD11cint Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in Mycobacterium avium-Infected Mice
Ketema Abdissa et al.
FRONTIERS IN IMMUNOLOGY (2018)
Reactive Oxygen Species as Regulators of MDSC-Mediated Immune Suppression
Kim Ohl et al.
FRONTIERS IN IMMUNOLOGY (2018)
Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations
Fatima Karzai et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Expression of Vascular Endothelial Growth Factor in Ovarian Cancer Inhibits Tumor Immunity through the Accumulation of Myeloid-Derived Suppressor Cells
Naoki Horikawa et al.
CLINICAL CANCER RESEARCH (2017)
Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells
Y. Deng et al.
ONCOGENE (2017)
PRKCI promotes immune suppression in ovarian cancer
Sharmistha Sarkar et al.
GENES & DEVELOPMENT (2017)
Circulating CD14+HLA-DR-/low myeloid-derived suppressor cells predicted early recurrence of hepatocellular carcinoma after surgery
Xing-Hui Gao et al.
HEPATOLOGY RESEARCH (2017)
An Immunogram Immunogram for the Cancer-Immunity Cycle: Towards Personalized Immunotherapy of Lung Cancer
Takahiro Karasaki et al.
JOURNAL OF THORACIC ONCOLOGY (2017)
Myeloid-derived suppressor cells are increased and correlated with type 2 immune responses, malnutrition, inflammation, and poor prognosis in patients with breast cancer
Kenji Gonda et al.
ONCOLOGY LETTERS (2017)
Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancer
Guoliang Yang et al.
ONCOTARGET (2017)
The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy
Hirokazu Shoji et al.
ONCOTARGET (2017)
Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma
Yago Pico de Coana et al.
ONCOTARGET (2017)
Interlekukin-6 Trans-Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Supressor Cells via Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer
Mengmeng Jiang et al.
FRONTIERS IN IMMUNOLOGY (2017)
CD39/CD73 upregulation on myeloid-derived suppressor cells via TGF--mTOR-HIF-1 signaling in patients with non-small cell lung cancer
Jieyao Li et al.
ONCOIMMUNOLOGY (2017)
CD13hi Neutrophil-like myeloid-derived suppressor cells exert immune suppression through Arginase 1 expression in pancreatic ductal adenocarcinoma
Jing Zhang et al.
ONCOIMMUNOLOGY (2017)
Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade
Chiara Secondini et al.
ONCOIMMUNOLOGY (2017)
Angiogenic, inflammatory and immunologic markers in predicting response to sunitinib in metastatic renal cell carcinoma
Ryuichi Mizuno et al.
CANCER SCIENCE (2017)
CXCL1 Is Critical for Premetastatic Niche Formation and Metastasis in Colorectal Cancer
Dingzhi Wang et al.
CANCER RESEARCH (2017)
Anti-PD-L1 Efficacy Can Be Enhanced by Inhibition of Myeloid-Derived Suppressor Cells with a Selective Inhibitor of PI3Kδ/γ
Ruth J. Davis et al.
CANCER RESEARCH (2017)
Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15-CCR1 Chemokine Axis
Susumu Inamoto et al.
CLINICAL CANCER RESEARCH (2016)
The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and sorafenib, but not sunitinib
Annkristin Heine et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2016)
Myeloid-derived suppressor cells correlate with patient outcomes in hepatic arterial infusion chemotherapy for hepatocellular carcinoma
Eishiro Mizukoshi et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2016)
Myeloid-Derived Suppressor Cells Express Bruton's Tyrosine Kinase and Can Be Depleted in Tumor-Bearing Hosts by Ibrutinib Treatment
Andrew Stiff et al.
CANCER RESEARCH (2016)
Invariant NKT cells are resistant to circulating CD15+ myeloid-derived suppressor cells in patients with head and neck cancer
Atsushi Horinaka et al.
CANCER SCIENCE (2016)
Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab
Alexander Martens et al.
CLINICAL CANCER RESEARCH (2016)
Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs)
Carlos Alfaro et al.
CLINICAL CANCER RESEARCH (2016)
Clinical Significance of Circulating CD33+ CD11b+HLA-DR- Myeloid Cells in Patients with Stage IV Melanoma Treated with Ipilimumab
Moshe Sade-Feldman et al.
CLINICAL CANCER RESEARCH (2016)
Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26
David Kung-Chun Chiu et al.
HEPATOLOGY (2016)
Myeloid-Derived Suppressor Cell Survival and Function Are Regulated by the Transcription Factor Nrf2
Daniel W. Beury et al.
JOURNAL OF IMMUNOLOGY (2016)
Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1
Celeste C. Goh et al.
JOURNAL OF IMMUNOLOGY (2016)
The clinical and prognostic significance of CD14+HLA-DR-/low myeloid-derived suppressor cells in hepatocellular carcinoma patients receiving radiotherapy
Dong Wang et al.
TUMOR BIOLOGY (2016)
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
Vincenzo Bronte et al.
NATURE COMMUNICATIONS (2016)
The prognostic effects of tumor infiltrating regulatory T cells and myeloid derived suppressor cells assessed by multicolor flow cytometry in gastric cancer patients
Han Sol Choi et al.
ONCOTARGET (2016)
Myeloid-Derived Suppressor Cells Are Controlled by Regulatory T Cells via TGF-β during Murine Colitis
Cho-Rong Lee et al.
CELL REPORTS (2016)
RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer
Ohad Tarcic et al.
CELL REPORTS (2016)
Phase I/II Study of Metastatic Melanoma Patients Treated with Nivolumab Who Had Progressed after Ipilimumab
Jeffrey Weber et al.
CANCER IMMUNOLOGY RESEARCH (2016)
Nitric oxide synthase 2 is involved in the pro-tumorigenic potential of γδ17 T cells in melanoma
Laetitia Douguet et al.
ONCOIMMUNOLOGY (2016)
Targeting inflammasome/IL-1 pathways for cancer immunotherapy
Beichu Guo et al.
SCIENTIFIC REPORTS (2016)
Increased circulating CD14(+) HLA-DR-/low myeloid-derived suppressor cells are associated with poor prognosis in patients with small-cell lung cancer
Tian Tian et al.
CANCER BIOMARKERS (2015)
Immunological factors influencing clinical outcome in lung cancer patients after telomerase peptide vaccination
Gaute Lund Hansen et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2015)
Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: a novel prognostic indicator
Han Zhang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2015)
Carbonic Anhydrase IX Promotes Myeloid-Derived Suppressor Cell Mobilization and Establishment of a Metastatic Niche by Stimulating G-CSF Production
Shawn C. Chafe et al.
CANCER RESEARCH (2015)
Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma
Ines Chevolet et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
Jeffrey S. Weber et al.
LANCET ONCOLOGY (2015)
Circulating CD14+HLA-DR-/low myeloid-derived suppressor cell is an indicator of poor prognosis in patients with ESCC
Haitao Huang et al.
TUMOR BIOLOGY (2015)
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation
Marianna Papaspyridonos et al.
NATURE COMMUNICATIONS (2015)
CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function
Eunyoung Chun et al.
CELL REPORTS (2015)
PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer
Jill J. Severson et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Immunoglobulin-like transcript 3 is expressed by myeloid-derived suppressor cells and correlates with survival in patients with non-small cell lung cancer
Pauline L. de Goeje et al.
ONCOIMMUNOLOGY (2015)
Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patients
Huanhuan Jiang et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Tasquinimod Modulates Suppressive Myeloid Cells and Enhances Cancer Immunotherapies in Murine Models
Li Shen et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Presence of circulating Her2-reactive CD8+T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients
Jithendra Kini Bailur et al.
BREAST CANCER RESEARCH (2015)
Myeloid-derived suppressor cell heterogeneity in human cancers
Samantha Solito et al.
YEAR IN IMMUNOLOGY: MYELOID CELLS AND INFLAMMATION (2014)
A combination trial of vaccine plus ipilimumab in metastatic castration-resistant prostate cancer patients: immune correlates
Caroline Jochems et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)
Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment
Caglar Cekic et al.
CANCER RESEARCH (2014)
IL-17A Produced by γδ T Cells Promotes Tumor Growth in Hepatocellular Carcinoma
Shoubao Ma et al.
CANCER RESEARCH (2014)
Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1-or Melan-A-Specific T Cells
Benjamin Weide et al.
CLINICAL CANCER RESEARCH (2014)
Inhibition of Tumor-Derived Prostaglandin-E2 Blocks the Induction of Myeloid-Derived Suppressor Cells and Recovers Natural Killer Cell Activity
Yumeng Mao et al.
CLINICAL CANCER RESEARCH (2014)
Phenotypes, accumulation, and functions of myeloid-derived suppressor cells and associated treatment strategies in cancer patients
Jingwei Jiang et al.
HUMAN IMMUNOLOGY (2014)
Adoptive cytotoxic T lymphocyte therapy triggers a counter-regulatory immunosuppressive mechanism via recruitment of myeloid-derived suppressor cells
Akihiro Hosoi et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
PD-L1 is a novel direct target of HIF-1α., and its blockade under hypoxia enhanced MDSC-mediated T cell activation
Muhammad Zaeem Noman et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Treatment of Tumors with Vitamin E Suppresses Myeloid Derived Suppressor Cells and Enhances CD8+T Cell-Mediated Antitumor Effects
Tae Heung Kang et al.
PLOS ONE (2014)
Adjuvants and myeloid-derived suppressor cells: Enemies or allies in therapeutic cancer vaccination
Audry Fernandez et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2014)
A Circulating Subpopulation of Monocytic Myeloid-Derived Suppressor Cells as an Independent Prognostic/Predictive Factor in Untreated Non-Small Lung Cancer Patients
Eleni-Kyriaki Vetsika et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2014)
Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab
Saskia J. A. M. Santegoetst et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2014)
Efficacy and safety of ipilimumab in metastatic melanoma patients surviving more than 2 years following treatment in a phase III trial (MDX010-20)
D. McDermott et al.
ANNALS OF ONCOLOGY (2013)
CXCR2-Expressing Myeloid-Derived Suppressor Cells Are Essential to Promote Colitis-Associated Tumorigenesis
Hiroshi Katoh et al.
CANCER CELL (2013)
Loss of SMAD4 From Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1+ Myeloid Cells and Facilitate Liver Metastasis
Yoshiro Itatani et al.
GASTROENTEROLOGY (2013)
Modulation of CD8+ T-cell activation events by monocytic and granulocytic myeloid-derived suppressor cells
Elio Schouppe et al.
IMMUNOBIOLOGY (2013)
Induction of myelodysplasia by myeloid-derived suppressor cells
Xianghong Chen et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Increased Myeloid-Derived Suppressor Cells in Gastric Cancer Correlate with Cancer Stage and Plasma S100A8/A9 Proinflammatory Proteins
Linda Wang et al.
JOURNAL OF IMMUNOLOGY (2013)
Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer
Jinpu Yu et al.
JOURNAL OF IMMUNOLOGY (2013)
Ipilimumab Treatment Results in an Early Decrease in the Frequency of Circulating Granulocytic Myeloid-Derived Suppressor Cells as well as Their Arginase1 Production
Yago Pico de Coana et al.
CANCER IMMUNOLOGY RESEARCH (2013)
Myeloid-Derived Suppressor Cells Attenuate TH1 Development through IL-6 Production to Promote Tumor Progression
Hirotake Tsukamoto et al.
CANCER IMMUNOLOGY RESEARCH (2013)
Immune Regulatory Activity of Vitamin D3 in Head and Neck Cancer
M. Young et al.
Cancers (2013)
Molecular mechanisms of T cell co-stimulation and co-inhibition
Lieping Chen et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Anti-IL-6 receptor mAb eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T-cell responses
Kentaro Sumida et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Programmed Death-1+ T Cells and Regulatory T Cells Are Enriched in Tumor-Involved Lymph Nodes and Associated with Aggressive Features in Papillary Thyroid Cancer
Jena D. French et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN
Yang Liu et al.
JOURNAL OF IMMUNOLOGY (2012)
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
Steffen Walter et al.
NATURE MEDICINE (2012)
Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer
Julie R. Brahmer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
Natasa Obermajer et al.
BLOOD (2011)
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells
Samantha Solito et al.
BLOOD (2011)
Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4+ T cells from patients with GI malignancy
Bethany L. Mundy-Bosse et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
Rachel F. Gabitass et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
PGE2-Induced CXCL12 Production and CXCR4 Expression Controls the Accumulation of Human MDSCs in Ovarian Cancer Environment
Natasa Obermajer et al.
CANCER RESEARCH (2011)
The PDL1-PD1 Axis Converts Human TH1 Cells into Regulatory T Cells
Shoba Amarnath et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Mesenchymal Transition and Dissemination of Cancer Cells Is Driven by Myeloid-Derived Suppressor Cells Infiltrating the Primary Tumor
Benjamin Toh et al.
PLOS BIOLOGY (2011)
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
Lucy S. K. Walker et al.
NATURE REVIEWS IMMUNOLOGY (2011)
TLR2-Mediated Expansion of MDSCs Is Dependent on the Source of Tumor Exosomes
Xiaoyu Xiang et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Direct and Differential Suppression of Myeloid-Derived Suppressor Cell Subsets by Sunitinib Is Compartmentally Constrained
Jennifer S. Ko et al.
CANCER RESEARCH (2010)
CARD9 Mediates Dectin-2-induced IκBα Kinase Ubiquitination Leading to Activation of NF-κB in Response to Stimulation by the Hyphal Form of Candida albicans
Liangkuan Bi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
F. Stephen Hodi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
Sergei Grivennikov et al.
CANCER CELL (2009)
Myeloid Derived Suppressor Cells Inhibit Natural Killer Cells in Patients with Hepatocellular Carcinoma via the NKp30 Receptor
Bastian Hoechst et al.
HEPATOLOGY (2009)
The T-cell-receptor signaling network
Morgan Huse
JOURNAL OF CELL SCIENCE (2009)
Fas Signal Promotes Lung Cancer Growth by Recruiting Myeloid-Derived Suppressor Cells via Cancer Cell-Derived PGE2
Yongliang Zhang et al.
JOURNAL OF IMMUNOLOGY (2009)
IL4Rα+ Myeloid-Derived Suppressor Cell Expansion in Cancer Patients
Susanna Mandruzzato et al.
JOURNAL OF IMMUNOLOGY (2009)
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
Kiavash Movahedi et al.
BLOOD (2008)
Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
Paolo Serafini et al.
CANCER RESEARCH (2008)
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
Pingyan Cheng et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells
Yulia Nefedova et al.
CANCER RESEARCH (2007)
Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1α, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells
Stefania Merighi et al.
MOLECULAR PHARMACOLOGY (2007)
The terminology issue for myeloid-derived suppressor cells
Dmitry I. Gabrilovich et al.
CANCER RESEARCH (2007)
Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
Paolo Serafini et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
B Huang et al.
CANCER RESEARCH (2006)
Prostaglandin E-2 synthesis and secretion: The role of PGE(2) synthases
Jean Y. Park et al.
CLINICAL IMMUNOLOGY (2006)
Tumor cells convert immature myeloid dendritic cells into TGF-β-secreting cells inducing CD4+CD25+ regulatory T cell proliferation
F Ghiringhelli et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Phase 1B study to improve immune responses in head and neck cancer patients using escalating doses of 25-hydroxyvitamin D3
DMR Lathers et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2004)
Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species
S Kusmartsev et al.
JOURNAL OF IMMUNOLOGY (2004)
Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism
A Mazzoni et al.
JOURNAL OF IMMUNOLOGY (2002)
Vitamin A deficiency in mice causes a systemic expansion of myeloid cells
T Kuwata et al.
BLOOD (2000)