☆ 4.7 Review

Frequency of Adverse Events in the Placebo Arms of COVID-19 Vaccine Trials A Systematic Review and Meta-analysis

JAMA NETWORK OPEN (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Medicine, General & Internal

Interim Results of a Phase 1-2a Trial of Ad26.COV2.S Covid-19 Vaccine

J. Sadoff et al.

Summary: The study conducted a multicenter, placebo-controlled, phase 1-2a trial, with participants randomly assigned to receive the Ad26.COV2.S vaccine. The results showed that the safety and immunogenicity profiles of the vaccine support further development.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

Safety and immunogenicity of S-Trimer (SCB-2019), a protein subunit vaccine candidate for COVID-19 in healthy adults: a phase 1, randomised, double-blind, placebo-controlled trial

Peter Richmond et al.

Summary: A study in Australia evaluated the dose-finding and adjuvant justification of the SCB-2019 vaccine against SARS-CoV-2. The vaccine, which contains a stabilised trimeric form of the spike protein (S-Trimer) combined with AS03 or CpG/Alum adjuvants, elicited robust humoral and cellular immune responses in both younger and older adults.

LANCET (2021)

添加到收藏夹

Article Immunology

A preliminary report of a randomized controlled phase 2 trial of the safety and immunogenicity of mRNA-1273 SARS-CoV-2 vaccine

Laurence Chu et al.

Summary: The study evaluated the safety and immunogenicity of the mRNA-1273 vaccine in healthy adults, showing significant immune responses to SARS-CoV-2 with acceptable safety profile. This vaccine induced higher antibody levels at a 100 mg dose, confirming its immunogenicity and safety for use in a 2-dose regimen.

VACCINE (2021)

添加到收藏夹

Review Immunology

International estimates of intended uptake and refusal of COVID-19 vaccines: A rapid systematic review and meta-analysis of large nationally representative samples

Eric Robinson et al.

Summary: The global willingness to uptake COVID-19 vaccines is decreasing while refusal to vaccinate is increasing. Factors such as gender, age, lower income and education levels, and belonging to ethnic minority groups are associated with lower intentions to vaccinate.

VACCINE (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

How do nocebo effects in placebo groups of randomized controlled trials provide a possible explicative framework for the COVID-19 pandemic?

Martina Amanzio et al.

Summary: This article examines the role of randomized clinical trials in understanding the nocebo effect during the COVID-19 pandemic, emphasizing the impact of individual and contextual factors on vaccine refusal.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2021)

添加到收藏夹

Article Infectious Diseases

Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1-2 dose-ranging study ,

Paul A. Goepfert et al.

Summary: The CoV2 preS dTM vaccine is being developed against SARS-CoV-2 and the interim results of the first-in-human study show lower than expected immune responses, especially in older age groups, and high reactogenicity after the second dose. Further development of the AS03-adjuvanted candidate vaccine will focus on identifying the optimal antigen formulation and dose.

LANCET INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Infectious Diseases

Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial

Keith J. Chappell et al.

Summary: The study evaluated the safety and immunogenicity of a novel COVID-19 vaccine, showing promising results in both aspects. Adverse reactions were minimal, and the vaccine elicited antigen-specific responses regardless of the dosage.

LANCET INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Safety and immunogenicity of the SARS-CoV-2 BNT162b1 mRNA vaccine in younger and older Chinese adults: a randomized, placebo-controlled, double-blind phase 1 study

Jingxin Li et al.

Summary: The messenger RNA vaccine candidate BNT162b1, encoding the receptor-binding domain of the SARS-CoV-2 spike protein, showed safety and high levels of humoral and T cell responses in an Asian population, including younger and older Chinese adults. Local reactions and systemic events post-vaccination were generally dose-dependent, transient, and mild to moderate.

NATURE MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant

S. A. Madhi et al.

Summary: The ChAdOx1 nCoV-19 vaccine did not provide significant protection against mild-to-moderate Covid-19 caused by the B.1.351 variant, with an efficacy of 10.4%. The incidence of serious adverse events was balanced between the vaccine and placebo groups.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant

V. Shinde et al.

Summary: The NVX-CoV2373 vaccine showed efficacy in preventing Covid-19, with higher vaccine efficacy observed among HIV-negative participants. Most infections were caused by the B.1.351 variant.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

添加到收藏夹

Article Medicine, General & Internal

Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine

Paul T. Heath et al.

Summary: The NVX-CoV2373 vaccine demonstrated an efficacy of 89.7% in a phase 3 trial with over 15,000 participants, with mild and transient reactogenicity. It showed high efficacy against the B.1.1.7 variant and a low incidence of adverse events.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Editorial Material Medicine, General & Internal

Covid-19 vaccination hesitancy

Mohammad S. Razai et al.

BMJ-BRITISH MEDICAL JOURNAL (2021)

添加到收藏夹

Article Health Policy & Services

COVID-19 Vaccination Hesitancy in the United States: A Rapid National Assessment

Jagdish Khubchandani et al.

Summary: The study found that 53% of American adults reported being very likely or somewhat likely to get a COVID-19 vaccine, while a significant proportion expressed hesitancy. Lower education level, lower income, and perception of lower risk of infection were associated with higher likelihood of vaccine hesitancy.

JOURNAL OF COMMUNITY HEALTH (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Seasonal influenza vaccine uptake among Chinese in Hong Kong: barriers, enablers and vaccination rates

Kai Sing Sun et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2020)

添加到收藏夹

Article Immunology

Why do parents not re-vaccinate their child for influenza? A prospective cohort study

Louise E. Smith et al.

VACCINE (2020)

添加到收藏夹

Article Medicine, General & Internal

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates

Edward E. Walsh et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

添加到收藏夹

Article Medicine, General & Internal

Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

Cheryl Keech et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

添加到收藏夹

Article Psychology, Multidisciplinary

A Proactive Approach for Managing COVID-19: The Importance of Understanding the Motivational Roots of Vaccination Hesitancy for SARS-CoV2

Steven Taylor et al.

FRONTIERS IN PSYCHOLOGY (2020)

添加到收藏夹

Article Allergy

Changing Patient Mindsets about Non-Life-Threatening Symptoms During Oral Immunotherapy: A Randomized Clinical Trial

Lauren C. Howe et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

Are Patients With Schizophrenia Spectrum Disorders More Prone to Manifest Nocebo-Like-Effects? A Meta-Analysis of Adverse Events in Placebo Groups of Double-Blind Antipsychotic Trials

Sara Palermo et al.

FRONTIERS IN PHARMACOLOGY (2019)

添加到收藏夹

Article Psychiatry

Minimizing Drug Adverse Events by Informing About the Nocebo Effect-An Experimental Study

Yiqi Pan et al.

FRONTIERS IN PSYCHIATRY (2019)

添加到收藏夹

Article Psychology, Multidisciplinary

The Influence of Side Effect Information Framing on Nocebo Effects

Kate Faasse et al.

ANNALS OF BEHAVIORAL MEDICINE (2019)

添加到收藏夹

Review Medicine, Research & Experimental

Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials

Jeremy Howick et al.

TRIALS (2018)

添加到收藏夹

Article Psychology, Clinical

Decreasing the Burden of Side Effects Through Positive Message Framing: an Experimental Proof-of-Concept Study

Marcel Wilhelm et al.

INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Untitled

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2017)

添加到收藏夹

Review Multidisciplinary Sciences

Barriers of Influenza Vaccination Intention and Behavior - A Systematic Review of Influenza Vaccine Hesitancy, 2005-2016

Philipp Schmid et al.

PLOS ONE (2017)

添加到收藏夹

Article Psychiatry

Nocebo in clinical trials for depression: A meta-analysis

Dimos D. Mitsikostas et al.

PSYCHIATRY RESEARCH (2014)

添加到收藏夹

Article Ethics

To Tell the Truth, the Whole Truth, May Do Patients Harm: The Problem of the Nocebo Effect for Informed Consent

Rebecca Erwin Wells et al.

AMERICAN JOURNAL OF BIOETHICS (2012)

添加到收藏夹

Article Anesthesiology

The hidden effects of blinded, placebo-controlled randomized trials: An experimental investigation

Winfried Rief et al.

PAIN (2012)

添加到收藏夹

Article Immunology

Theory-based predictors of influenza vaccination among pregnant women

Jessica R. Gorman et al.

VACCINE (2012)

添加到收藏夹

Article Public, Environmental & Occupational Health

Assessing general side effects in clinical trials: reference data from the general population

Winfried Rief et al.

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2011)

添加到收藏夹

Article Immunology

College students' perceptions of H1N1 flu risk and attitudes toward vaccination

Meagan A. Ramsey et al.

VACCINE (2011)

添加到收藏夹

Article Medicine, General & Internal

The Cochrane Collaboration's tool for assessing risk of bias in randomised trials

Julian P. T. Higgins et al.

BMJ-BRITISH MEDICAL JOURNAL (2011)

添加到收藏夹

Review Public, Environmental & Occupational Health

Differences in Adverse Effect Reporting in Placebo Groups in SSRI and Tricyclic Antidepressant Trials A Systematic Review and Meta-Analysis

Winfried Rief et al.

DRUG SAFETY (2009)

添加到收藏夹

Review Anesthesiology

A systematic review of adverse events in placebo groups of anti-migraine clinical trials

Martina Amanzio et al.

PAIN (2009)

添加到收藏夹

Review Neurosciences

When words are painful: Unraveling the mechanisms of the nocebo effect

F. Benedetti et al.

NEUROSCIENCE (2007)

添加到收藏夹

Article Neurosciences

The biochemical and neuroendocrine bases of the hyperalgesic nocebo effect

Fabrizio Benedetti et al.

JOURNAL OF NEUROSCIENCE (2006)

添加到收藏夹

Article Medicine, General & Internal

Nonspecific medication side effects and the nocebo phenomenon

AJ Barsky et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.