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INTERNATIONAL JOURNAL OF CANCER (2020)
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V. Prasad et al.
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V. Subbiah et al.
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Aurelien Marabelle et al.
LANCET ONCOLOGY (2020)
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Neal Ready et al.
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Aparna R. Parikh et al.
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Aaron M. Goodman et al.
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Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic
T. A. Chan et al.
ANNALS OF ONCOLOGY (2019)
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Robert M. Samstein et al.
NATURE GENETICS (2019)
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Reinhard Buettner et al.
ESMO OPEN (2019)
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James Larkin et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
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Hossein Maymani et al.
LUNG CANCER (2018)
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Mohamed E. Salem et al.
MOLECULAR CANCER RESEARCH (2018)
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Carl Morrison et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
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Aaron M. Goodman et al.
MOLECULAR CANCER THERAPEUTICS (2017)
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D. P. Carbone et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
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Roman Groisberg et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
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Eytan Ben-Ami et al.
CANCER (2017)
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Maria Schwaederle et al.
MOLECULAR CANCER THERAPEUTICS (2016)
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
D. T. Le et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
Alexandra Snyder et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)