Recent developments concerning the investigation of exocytosis with amperometry

In this article, we have summarized the recent important re-sults related to the electrochemical detection of vesicular exocytosis by amperometry with microelectrodes over the past three years. In this fascinating scientific field that began 40 years ago, the historical carbon fiber amperometry method still continues to be used to address biological questions by the pioneered groups of the field but also by other research groups thus showing this has become an indispensable routine tech-nique for analyzing exocytosis. Furthermore, new methodolo-gies (coupling with fluorescence, use of nanoelectrodes, microarrays) have blossomed and demonstrated how new analytical methods could be built to push back the limits of the initial technique.

Automated summary

In this article, recent important results related to the electrochemical detection of vesicular exocytosis by amperometry with microelectrodes over the past three years have been summarized. The historical carbon fiber amperometry method continues to be widely used in this scientific field, and new methodologies have emerged to expand the limits of the initial technique, demonstrating the advancement in the field. The development of exocytosis analysis techniques has become an indispensable routine experimental technique.