The omicron variant of SARS-CoV-2: Understanding the known and living with unknowns COMMENT

The recently discovered Omicron variant of SARS-CoV-2 has rapidly burst into the public and scientific eye, being detected in more than 26 countries around the world. Given its more than 50 mutations, there is widespread concern about its public health impact, leading the World Health Organization to designate it a variant of concern. This Commentary provides a summary of current knowledge and unknowns about this viral variant as of December 2, 2021 and summarizes the key questions that need to be rapidly answered.

Automated summary

The recently discovered Omicron variant of SARS-CoV-2 has raised global concern due to its more than 50 mutations and potential impact on public health. Current knowledge about this viral variant is limited, and there is a need to rapidly address key questions surrounding it.