4.6 Article

Polarization-Singular Approach to Imaging Mueller-Matrix Polarimetry in the Differential Diagnosis of Histological Sections of Biopsy of Tumors of the Uterus and Prostate

期刊

FRONTIERS IN PHYSICS
卷 9, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fphy.2021.711212

关键词

mueller matrix; singularity; polarization; S and C-state; optical anisotropy; birefringence; biological tissue; statistical moments

资金

  1. National Research Foundation of Ukraine [2020.02/0061]

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The diagnostic use of a singular approach in analyzing polarization properties of histological biopsy sections has proven effective in differentiating between benign and malignant tumors of the uterus and prostate. The azimuthal-invariant express method of Mueller-matrix mapping has shown promising sensitivity, specificity, and accuracy in the differential diagnosis of uterine myoma and adenocarcinoma, as well as adenocarcinoma of the prostate with varying degrees of differentiation.
The possibilities of the diagnostic use of the singular approach of the distributions of the number of characteristic values of the MMI is effective for differentiating the polarization properties of histological biopsy sections of benign and malignant tumours of the uterus and prostate. Within the framework of evidence-based medicine, the sensitivity, specificity and accuracy of the azimuthal-invariant express (similar to 15 min) method of Mueller-matrix mapping of polarization-singular states in the differential diagnosis of uterine myoma and adenocarcinoma, as well as adenocarcinoma of the prostate with varying degrees of differentiation have been determined.

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