期刊
ASIAN JOURNAL OF PSYCHIATRY
卷 67, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.ajp.2021.102927
关键词
Comorbidity patterns; Multimorbidity; Schizotypal disorders; Psychiatric inpatient; Association rule mining (ARM)
类别
资金
- Scientific Research Seed Fund of Peking University First Hospital [2021SF62]
- China Medical Board (CMBOC) [17-278]
Among patients with schizophrenia, extrapyramidal syndrome, constipation, and tachycardia were the most common comorbidities. Specific comorbidity combinations were associated with longer length of stay, higher daily expenses, and increased risk of readmission.
Background: Comorbidities are common among patients with schizophrenia yet the prevalence of comorbidity combinations and their associations with inpatient service utilization and readmission have been scarcely explored. Methods: Data were extracted from discharge summaries of patients whose primary diagnosis was schizophrenia spectrum disorders (ICD-10: F20-F29). We identified 30 most frequent comorbidities in patients' secondary diagnoses and then used the association rule mining (ARM) method to derive comorbidity combinations associated with length of stay (LOS), daily expense and one-year readmission. Results: The study included data from 8252 patients. The top five most common comorbidities were extrapyramidal syndrome (EPS, 44.58%), constipation (31.63%), common cold (21.80%), hyperlipidemia (20.99%) and tachycardia (19.13%). Most comorbidity combinations identified by ARM were significantly associated with longer LOS (>= 70 days), few were associated with higher daily expenses, and fewer with readmission. The 3-way combination of common cold, hyperlipidemia and fatty liver had the strongest association with longer LOS (adjusted OR (aOR): 3.38, 95% CI: 2.12-5.38). The combination of EPS and mild cognitive disorder was associated with higher daily expense (>= 700 RMB) (aOR: 1.67, 95% CI: 1.20-2.31). The combination of constipation, tachycardia and fatty liver were associated with higher 1-year readmission (aOR: 2.05, 95% CI: 1.03-4.09). Conclusion: EPS, constipation, and tachycardia were among the most commonly reported comorbidities in schizophrenia patients in Beijing, China. Specific groups of comorbidities may contribute to higher inpatient psychiatric service utilization and readmission. The mechanism behind the associations and potential interventions to optimize service use warrant further investigation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据