4.6 Article

Identification of Novel Diagnostic Markers for Malignant Pleural Mesothelioma Using a Reverse Translational Approach Based on a Rare Synchronous Tumor

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Summary: The study identified multiple molecular signatures associated with the progression of malignant pleural mesothelioma, including genes involved in cell adhesion, extracellular matrix organization, mitotic cell division, and apoptosis inhibition. Some proteins were found to potentially drive tumorigenesis, suggesting they could be targets for novel therapies. Further research with small-molecule inhibitors or silencing RNAs is warranted to evaluate the cancer-driving role of the identified targets.

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