期刊
DIAGNOSTICS
卷 11, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/diagnostics11112158
关键词
sarcopenia; ultrasonography; muscle; muscle thickness; muscle stiffness
资金
- University of Piemonte Orientale Research Funds at the Health Sciences Department
- Cariplo Foundation at the Maggiore della Carita hospital [2017-0604]
This study evaluated the reliability of ultrasound assessment of tibialis anterior muscle in diagnosing sarcopenia. The study found a significant correlation between reduced tibialis anterior muscle thickness and SarQoL values, hand grip strength, and skeletal muscle index. Ultrasound assessment of tibialis anterior muscle may be considered a reliable tool for evaluating sarcopenia.
Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 & PLUSMN; 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 & PLUSMN; 4.92 vs. 28.94 & PLUSMN; 3.63 mm, p < 0.05) with significant correlation with SarQoL values (r = 0.80, p < 0.05), dynamometer hand strength (r = 0.72, p < 0.05) and SMI (r = 0.76, p < 0.05). Moreover, we found reduced stiffness (32.21 & PLUSMN; 12.31 vs. 27.07 & PLUSMN; 8.04 Kpa, p < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia.
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