期刊
ACS OMEGA
卷 7, 期 5, 页码 -出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsomega.1c06029
关键词
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资金
- National Natural Science Foundation of China [81602973]
- Scientific Research Project of the Education Department of Anhui Province [KJ2021A0883]
- Talent Funds of Anhui Science and Technology University
In this study, a one-step electrochemical tandem sp(3)(C-H) double amination was developed for the efficient synthesis of 3-acyl imidazo[1,5-a]pyridines, eliminating the need for the conventional three-step reaction.
3-Acyl imidazo[1,5-a]pyridines, featured pharmaceutical moi-eties that were prepared by a three-step reaction conventionally, could be obtained in one step by an electrochemical tandem sp(3) (C-H) double amination of acetophenones with pyridine ethylamines using ammonium iodide as a redox mediator.
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