4.6 Article

Oxoanion Imprinting Combining Cationic and Urea Binding Groups: A Potent Glyphosate Adsorber

期刊

ACS OMEGA
卷 7, 期 1, 页码 587-598

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acsomega.1c05079

关键词

-

资金

  1. Marie Sklodowska-Curie Actions [H2020-MSCA-ITN-2016, 722171]
  2. Vetenskapsradet (VR) [2014-3794]
  3. Sweden Knowledge-Foundation (KKS) [20150086]
  4. Marie Curie Actions (MSCA) [722171] Funding Source: Marie Curie Actions (MSCA)

向作者/读者索取更多资源

The study involved polymerizable hosts in anion imprinting to create receptors with high oxyanion affinity and specificity in both aqueous and non-aqueous environments. By comparing hydrophobic and hydrophilic crosslinking monomers, optimal conditions for oxyanion binding in different media were identified.
The use of polymerizable hosts in anion imprinting has led to powerful receptors with high oxyanion affinity and specificity in both aqueous and non-aqueous environments. As demonstrated in previous reports, a carefully tuned combination of orthogonally interacting binding groups, for example, positively charged and neutral hydrogen bonding monomers, allows receptors to be constructed for use in either organic or aqueous environments, in spite of the polymer being prepared in non-competitive solvent systems. We here report on a detailed experimental design of phenylphosphonic and benzoic acid-imprinted polymer libraries prepared using either urea- or thiourea-based host monomers in the presence or absence of cationic comonomers for charge-assisted anion recognition. A comparison of hydrophobic and hydrophilic crosslinking monomers allowed optimum conditions to be identified for oxyanion binding in non-aqueous, fully aqueous, or high-salt media. This showed that recognition improved with the water content for thiourea-based molecularly imprinted polymers (MIPs) based on hydrophobic EGDMA with an opposite behavior shown by the polymers prepared using the more hydrophilic crosslinker PETA. While the affinity of thiourea-based MIPs increased with the water content, the opposite was observed for the oxourea counterparts. Binding to the latter could however be enhanced by raising the pH or by the introduction of cationic amine- or Na+-complexing crown ether-based comonomers. Use of high-salt media as expected suppressed the amine-based charge assistance, whereas it enhanced the effect of the crown ether function. Use of the optimized receptors for removing the ubiquitous pesticide glyphosate from urine finally demonstrated their practical utility.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据