4.6 Article

Cetylpyridinium Trichlorostannate: Synthesis, Antimicrobial Properties, and Controlled-Release Properties via Electrical Resistance Tomography

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ACS OMEGA
卷 6, 期 51, 页码 35433-35441

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AMER CHEMICAL SOC
DOI: 10.1021/acsomega.1c04034

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  1. NIAID [1R01AI139100-01]

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The compound CPC-Sn, consisting of cetylpyridinium chloride and stannous chloride, was synthesized and characterized with single-crystal X-ray diffraction, revealing a 1:1 ratio of cetylpyridinium cation and [SnCl3](-) anion. It has potential applications as a broad-spectrum antimicrobial agent and for producing advanced functional materials. Electrical resistance tomography showed that CPC-Sn has extended-release properties in aqueous environments compared to CPC.
Cetylpyridinium trichlorostannate (CPC-Sn), comprising cetylpyridinium chloride (CPC) and stannous chloride, was synthesized and characterized via single-crystal X-ray diffraction measurements indicating stoichiometry of C21H38NSnCl3 where the molecules are arranged in a 1:1 ratio with a cetylpyridinium cation and a [SnCl3](-) anion. CPC-Sn has shown potential for application as a broad-spectrum antimicrobial agent, to reduce bacteria-generated volatile sulfur compounds and to produce advanced functional materials. In order to investigate its controlled-release properties, electrical resistance tomography was implemented. The results demonstrate that CPC-Sn exhibits extended-release properties in an aqueous environment as opposed to the CPC counterpart.

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