期刊
ANTIBIOTICS-BASEL
卷 11, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/antibiotics11020191
关键词
Schiff bases; antibacterials; imine; nanoparticles; chitosan; antimicrobials; chitosan-based Schiff bases
资金
- Department of Pharmacy, Health and Nutritional Sciences of the University of Calabria (Italy)
- Sistema Integrato di Laboratori per L'Ambiente-(SILA) [PONa3_00341]
Schiff bases have a wide range of applications in various fields and their conjugation with chitosan can enhance chitosan's antibacterial activity. The use of Schiff base nanoparticles can also improve their antimicrobial effects.
Schiff bases (SBs) have extensive applications in different fields such as analytical, inorganic and organic chemistry. They are used as dyes, catalysts, polymer stabilizers, luminescence chemosensors, catalyzers in the fixation of CO2 biolubricant additives and have been suggested for solar energy applications as well. Further, a wide range of pharmacological and biological applications, such as antimalarial, antiproliferative, analgesic, anti-inflammatory, antiviral, antipyretic, antibacterial and antifungal uses, emphasize the need for SB synthesis. Several SBs conjugated with chitosan have been studied in order to enhance the antibacterial activity of chitosan. Moreover, the use of the nanoparticles of SBs may improve their antimicrobial effects. Herein, we provide an analytical overview of the antibacterial and antifungal properties of SBs and chitosan-based SBs as well as SBs-functionalized nanoparticles. The most relevant and recent literature was reviewed for this purpose.
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