Increased 1-year mortality in haemodialysis patients with COVID-19: a prospective, observational study

Article Emergency Medicine

On-admission anemia predicts mortality in COVID-19 patients: A single center, retrospective cohort study

Seung Mi Oh et al.

Summary: This study investigated the impact of anemia based on admission hemoglobin (Hb) level as a prognostic risk factor for severe outcomes in hospitalized patients with coronavirus disease 2019 (COVID-19).

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2021)

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Article Medicine, Research & Experimental

Anemia in patients with Covid-19: pathogenesis and clinical significance

Gaetano Bergamaschi et al.

Summary: COVID-19 patients commonly present with anemia, which is usually mild and inflammation-related, sometimes associated with iron and/or vitamin deficiencies. Determinants of hemoglobin concentration include erythrocyte sedimentation rate, serum cholinesterase, ferritin and protein concentrations, and number of chronic diseases affecting each patient. Hemoglobin concentration is not related to overall survival, but is influenced by red blood cell distribution width, age, lactate dehydrogenase, and the ratio of arterial partial oxygen pressure to inspired oxygen fraction.

CLINICAL AND EXPERIMENTAL MEDICINE (2021)

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Review Urology & Nephrology

Mortality in chronic kidney disease patients with COVID-19: a systematic review and meta-analysis

Ruyi Cai et al.

Summary: The outbreak of COVID-19 in 2020 led to a global pandemic, with significantly higher mortality rates among patients with chronic kidney disease who are infected with the virus, necessitating comprehensive multidisciplinary management strategies.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2021)

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Article Transplantation

Chronic kidney disease is a key risk factor for severe COVID-19: a call to action by the ERA-EDTA

Alberto Ortiz et al.

Summary: Diabetes, hypertension, and cardiovascular disease have been traditionally considered risk factors for severe COVID-19, but recent studies have found that renal disease, especially dialysis, organ transplantation, and CKD, play a significant role in the mortality risk associated with COVID-19.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

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Article Urology & Nephrology

Determinants of mortality in a large group of hemodialysis patients hospitalized for COVID-19

Kenan Turgutalp et al.

Summary: This study revealed a high mortality rate among hospitalized MHD patients with COVID-19. Risk factors for mortality included older age, heart failure, disease severity, ferritin level, platelet count decrease, and AST level increase.

BMC NEPHROLOGY (2021)

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Article Urology & Nephrology

Suboptimal personal protective equipment and SARS-CoV-2 infection in Nephrologists: a Spanish national survey

Borja Quiroga et al.

Summary: This study found that SARS-CoV-2 infection was common among nephrologists during the COVID-19 pandemic, with most infections occurring in the first wave and a lack of appropriate personal protective equipment being identified as a major predictive factor for infection.

CLINICAL KIDNEY JOURNAL (2021)

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Article Infectious Diseases

Anemia predicts poor outcomes of COVID-19 in hospitalized patients: a prospective study in Iran

Masood Faghih Dinevari et al.

Summary: The study found a high prevalence of anemia in hospitalized COVID-19 patients, which was associated with poor outcomes of the disease.

BMC INFECTIOUS DISEASES (2021)

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Article Urology & Nephrology

Kinetics of Anti?SARS-CoV-2 IgG Antibodies in Hemodialysis Patients Six Months after Infection

Hamza Sakhi et al.

Summary: This study investigates the long-term kinetics of the antibody response to SARS-CoV-2 in dialysis patients who recovered from COVID-19, revealing that 10% of patients had no initial seroconversion and IgG antibodies decayed over time. Factors associated with decline in antibodies included older age, female sex, and nonsevere clinical presentation. About 25% of patients had negative IgG antinucleocapsid serology after 6 months, while most patients maintained antispike antibodies.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)

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Article Hematology

Prolonged elevation of D-dimer levels in convalescent COVID-19 patients is independent of the acute phase response

Liam Townsend et al.

Summary: A study analyzed 150 COVID-19 patients and found that some recovered patients experienced persistent symptoms like fatigue, breathlessness, and reduced exercise tolerance, potentially related to sustained elevation of D-dimer levels. Although other coagulation and inflammation markers had normalized in the majority of convalescent patients, elevated D-dimers were still present in a significant portion, highlighting the importance of investigating the biological mechanisms underlying long COVID and implications for clinical management.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2021)

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Article Physiology

Clinical Features of Asymptomatic SARS-CoV-2 Infection in Hemodialysis Patients

Maria Soledad Pizarro-Sanchez et al.

Summary: The study showed that asymptomatic SARS-CoV-2 infection is common in hemodialysis patients, especially among patients who initially test negative on PCR but later develop antibodies. Laboratory evidence indicates that asymptomatic patients have milder disease. COVID-19 mortality in hemodialysis patients may be lower than previously estimated based on PCR tests alone.

KIDNEY & BLOOD PRESSURE RESEARCH (2021)

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Article Urology & Nephrology

Tasa de ultrafiltración horaria ajustada a peso corporal y mortalidad en hemodiálisis

Raul Fernandez-Prado et al.

NEFROLOGIA (2021)

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Article Urology & Nephrology

Rapid decline of anti-SARS-CoV-2 antibodies in patients on haemodialysis: the COVID-FRIAT study

Roberto Alcazar-Arroyo et al.

Summary: Research suggests that the anti-SARS-CoV-2 antibody immune response in HD patients varies depending on clinical presentation, with antibody titres decaying earlier than in the general population. The probability of developing an adequate serologic response is higher in patients with symptomatic COVID-19.

CLINICAL KIDNEY JOURNAL (2021)

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Article Virology

Association of anemia and COVID-19 in hospitalized patients

Chong Chen et al.

Summary: This study investigates the association between anemia and severe pneumonia in COVID-19 patients. It found that anemic patients were less likely to develop fever in the early stage of COVID-19, had elevated IL-6 levels, and were more likely to develop severe pneumonia.

FUTURE VIROLOGY (2021)

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Editorial Material Infectious Diseases

Long COVID has exposed medicine's blind-spot

Matthew J. Burke et al.

LANCET INFECTIOUS DISEASES (2021)

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Letter Biochemistry & Molecular Biology

Causation or confounding: why controls are critical for characterizing long COVID

Zahin Amin-Chowdhury et al.

NATURE MEDICINE (2021)

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Letter Urology & Nephrology

SARS-CoV-2 infection in chronic kidney disease patients vaccinated with Oxford/AstraZeneca COVID-19 vaccine: initial Indian experience

Sanshriti Chauhan et al.

CLINICAL KIDNEY JOURNAL (2021)

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Article Urology & Nephrology

Impaired Immune Response to SARS-CoV-2 Vaccination in Dialysis Patients and in Kidney Transplant Recipients

Thilo Kolb et al.

Summary: Patients with kidney failure, especially kidney transplant recipients, have weaker antibody responses to COVID-19 vaccines, with a majority of KTRs not developing neutralizing antibodies after vaccination. These findings suggest the need for modification of vaccination strategies in KTRs and patients on dialysis.

KIDNEY360 (2021)

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Letter Biochemistry & Molecular Biology

Longitudinal dynamics of antibody responses in recovered COVID-19 patients

Meng-Li Cheng et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

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Article Physiology

The COVID-19 Epidemic: Management and Outcomes of Hemodialysis and Peritoneal Dialysis Patients in Stockholm, Sweden

Jessica Smolander et al.

Summary: A study in Stockholm reported on the management and outcomes of 40 hemodialysis and 4 peritoneal dialysis patients with symptomatic COVID-19. The study found that hemodialysis patients over 70 years old had higher mortality rates, while patients under 70 seemed to have milder disease.

KIDNEY & BLOOD PRESSURE RESEARCH (2021)

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Letter Cardiac & Cardiovascular Systems

Delayed catastrophic thrombotic events in young and asymptomatic post COVID-19 patients

Bingwen Eugene Fan et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2021)

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Article Health Care Sciences & Services

Incidence and Clinical Impacts of COVID-19 Infection in Patients with Hemodialysis: Systematic Review and Meta-Analysis of 396,062 Hemodialysis Patients

Chun-Yu Chen et al.

Summary: A total of 3261 confirmed COVID-19 cases were identified in 29 articles from a pool of 396,062 HD patients. The incidence of COVID-19 in these HD patients was 7.7%, with an overall mortality rate of 22.4%. Reported estimates were higher in non-Asian countries compared to Asian countries. Study quality may affect the reported incidence but not the mortality among studies.

HEALTHCARE (2021)

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Article Medicine, General & Internal