相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Drug similarity and structure-based screening of medicinal compounds to target macrodomain-I from SARS-CoV-2 to rescue the host immune system: a molecular dynamics study
Zainib Babar et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)
High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain
Morgan Dasovich et al.
ACS CHEMICAL BIOLOGY (2022)
ADP-ribosyltransferases, an update on function and nomenclature
Bernhard Luscher et al.
FEBS JOURNAL (2022)
Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis and poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets
Carla Mavian et al.
JOURNAL OF NEUROVIROLOGY (2021)
Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design
Sixue Zhang et al.
PLOS ONE (2021)
Identification of FDA approved drugs and nucleoside analogues as potential SARS-CoV-2 A1pp domain inhibitor: An in silico study
Atul Kumar Singh et al.
COMPUTERS IN BIOLOGY AND MEDICINE (2021)
Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity
Aravinth Kumar Jayabalan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Unique Mutations in the Murine Hepatitis Virus Macrodomain Differentially Attenuate Virus Replication, Indicating Multiple Roles for the Macrodomain in Coronavirus Replication
Lynden S. Voth et al.
JOURNAL OF VIROLOGY (2021)
The SARS-CoV-2 RNA interactome
Sungyul Lee et al.
MOLECULAR CELL (2021)
Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain
Xiaomin Ni et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
Marion Schuller et al.
SCIENCE ADVANCES (2021)
High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors Against Mac1 Domain of SARS-CoV-2 Nsp3
Chandrabose Selvaraj et al.
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS (2021)
The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling
Lilian Cristina Russo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Antivirals against the Chikungunya Virus
Verena Battisti et al.
VIRUSES-BASEL (2021)
Clinical and molecular characteristics of COVID-19 patients with persistent SARS-CoV-2 infection
Bin Yang et al.
NATURE COMMUNICATIONS (2021)
Exploring protein hotspots by optimized fragment pharmacophores
David Bajusz et al.
NATURE COMMUNICATIONS (2021)
ADP-ribosyltransferase PARP11 suppresses Zika virus in synergy with PARP12
Lili Li et al.
CELL AND BIOSCIENCE (2021)
Persistence of SARS-CoV-2 RNA in lung tissue after mild COVID-19
Laurens J. Ceulemans et al.
LANCET RESPIRATORY MEDICINE (2021)
A molecular toolbox for ADP-ribosyl binding proteins
Sven T. Sowa et al.
CELL REPORTS METHODS (2021)
Coronavirus persistence in human respiratory tract and cell culture: An overview
Adriana Gaspar-Rodriguez et al.
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES (2021)
The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase
Yousef M. O. Alhammad et al.
JOURNAL OF VIROLOGY (2021)
(ADP-ribosyl)hydrolases: structure, function, and biology
Johannes Gregor Matthias Rack et al.
GENES & DEVELOPMENT (2020)
The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions
Anthony R. Fehr et al.
GENES & DEVELOPMENT (2020)
Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice
Rachy Abraham et al.
MBIO (2020)
Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection
Irina C. Albulescu et al.
VIRUSES-BASEL (2020)
The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation
Yousef M. O. Alhammad et al.
VIRUSES-BASEL (2020)
Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3
David N. Frick et al.
BIOCHEMISTRY (2020)
In Silico Identification of Potential Inhibitors of ADP-Ribose Phosphatase of SARS-CoV-2 nsP3 by Combining E-Pharmacophore- and Receptor-Based Virtual Screening of Database
Pradip Debnath et al.
CHEMISTRYSELECT (2020)
Drug Discovery Strategies for SARS-CoV-2
Zeenat A. Shyr et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2020)
Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity
Collin D. Heer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3
Rajdeep S. Virdi et al.
SLAS DISCOVERY (2020)
Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential
Johannes Gregor Matthias Rack et al.
OPEN BIOLOGY (2020)
Comparison of Binding Site of Remdesivir and Its Metabolites with NSP12-NSP7-NSP8, and NSP3 of SARS CoV-2 Virus and Alternative Potential Drugs for COVID-19 Treatment
Lindsey S. Jung et al.
PROTEIN JOURNAL (2020)
Association of persistent wild-type measles virus RNA with long-term humoral immunity in rhesus macaques
Ashley N. Nelson et al.
JCI INSIGHT (2020)
Shared and Distinct Functions of Type I and Type III Interferons
Helen M. Lazear et al.
IMMUNITY (2019)
ADP-ribosylation signalling and human disease
Luca Palazzo et al.
OPEN BIOLOGY (2019)
The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression
Matthew E. Grunewald et al.
PLOS PATHOGENS (2019)
ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP
Tingting Guo et al.
NATURE MICROBIOLOGY (2019)
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes
Rudragouda Channappanavar et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins
Lili Li et al.
SCIENCE SIGNALING (2018)
Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis
Anthony R. Fehr et al.
TRENDS IN MICROBIOLOGY (2018)
Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases
Anthony K. L. Leung et al.
PLOS PATHOGENS (2018)
PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins
Lili Li et al.
SCIENCE SIGNALING (2018)
ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication
Rachy Abraham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence
Robert Lyle McPherson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses
Andrew E. Shaw et al.
PLOS BIOLOGY (2017)
The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases
Laura Eckei et al.
SCIENTIFIC REPORTS (2017)
Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14
Marion Schuller et al.
ACS CHEMICAL BIOLOGY (2017)
Macrodomains: Structure, Function, Evolution, and Catalytic Activities
Johannes Gregor Matthias Rack et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)
Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles
Benjamin W. Neuman
ANTIVIRAL RESEARCH (2016)
Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice
Rudragouda Channappanavar et al.
CELL HOST & MICROBE (2016)
Chikungunya: Its History in Africa and Asia and Its Spread to New Regions in 2013-2014
Herve Zeller et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
Viral Macro Domains Reverse Protein ADP-Ribosylation
Changqing Li et al.
JOURNAL OF VIROLOGY (2016)
Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense
Taisho Yamada et al.
NATURE IMMUNOLOGY (2016)
The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection
Anthony R. Fehr et al.
MBIO (2016)
Nudix hydrolases degrade protein-conjugated ADP-ribose
Casey M. Daniels et al.
SCIENTIFIC REPORTS (2015)
Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
Julie Dyall et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Phosphoproteomic Approach to Characterize Protein Mono- and Poly(ADP-ribosyl)ation Sites from Cells
Casey M. Daniels et al.
JOURNAL OF PROTEOME RESEARCH (2014)
Interferon-Stimulated Poly(ADP-Ribose) Polymerases Are Potent Inhibitors of Cellular Translation and Virus Replication
Svetlana Atasheva et al.
JOURNAL OF VIROLOGY (2014)
Chikungunya virus: an update on antiviral development and challenges
Parveen Kaur et al.
DRUG DISCOVERY TODAY (2013)
Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases
Florian Rosenthal et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation
Gytis Jankevicius et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Alphaviruses: Population genetics and determinants of emergence
Scott C. Weaver et al.
ANTIVIRAL RESEARCH (2012)
New PARP Gene with an Anti-Alphavirus Function
Svetlana Atasheva et al.
JOURNAL OF VIROLOGY (2012)
Prolonged persistence of measles virus RNA is characteristic of primary infection dynamics
Wen-Hsuan W. Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Alphavirus-Induced Encephalomyelitis: Antibody-Secreting Cells and Viral Clearance from the Nervous System
Talibah U. Metcalf et al.
JOURNAL OF VIROLOGY (2011)
Chronic pain associated with the Chikungunya Fever: long lasting burden of an acute illness
Daniel Ciampi de Andrade et al.
BMC INFECTIOUS DISEASES (2010)
Persistent Chronic Inflammation and Infection by Chikungunya Arthritogenic Alphavirus in Spite of a Robust Host Immune Response
Jean-Jacques Hoarau et al.
JOURNAL OF IMMUNOLOGY (2010)
The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket
Helene Malet et al.
JOURNAL OF VIROLOGY (2009)
Impact of Chikungunya Virus Infection on Health Status and Quality of Life: A Retrospective Cohort Study
Man-Koumba Soumahoro et al.
PLOS ONE (2009)
The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice
Eunhye Park et al.
VIROLOGY (2009)
Persistent arthralgia associated with chikungunya virus: A study of 88 adult patients on Reunion Island
Gianandrea Borgherini et al.
CLINICAL INFECTIOUS DISEASES (2008)
The macro domain is an ADP-ribose binding module
GI Karras et al.
EMBO JOURNAL (2005)