期刊
PATHOGENS
卷 10, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/pathogens10121630
关键词
antimicrobial resistance; broiler; Campylobacter jejuni; Campylobacter coli; organic; cgMLST; chicken; quinolones; whole-genome sequencing
类别
资金
- Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (Formas) [2016-01143]
- Formas [2016-01143] Funding Source: Formas
The study found that Campylobacter isolates from organic chickens were generally sensitive to antibiotics, while a portion of isolates from conventional chickens showed resistance to quinolones and tetracycline. There were shared sequence types between organic and conventional chickens, but two sequence types from conventional chickens exhibited different resistance phenotypes compared to the rest.
Antibiotic resistance is a major challenge worldwide and increased resistance to quinolones in Campylobacter is being reported. Analysis of antibiotic resistance was performed on 157 Campylobacter strains (123 C. jejuni and 34 C. coli) from conventional and organic chickens produced in Sweden. Susceptibility for tetracycline, ciprofloxacin, erythromycin, nalidixic acid, streptomycin, and gentamycin was determined by microdilution. All 77 isolates from organic chickens were sensitive to all antibiotics, except two C. jejuni that were resistant to tetracycline. Of the 80 isolates from conventional chickens, 22.5% of C. jejuni and 11.1% of C. coli were resistant to quinolones and 5.6% of C. jejuni were resistant to tetracycline. Whole-genome sequencing resulted in 50 different sequence types of C. jejuni and six of C. coli. Nine sequence types were found in both organic and conventional chickens. Two of these (ST-19 and ST-257) included isolates from conventional broilers with different resistance phenotypes to the remaining isolates from conventional and organic broilers. There are management differences between the production systems, such as feed, breed, use of coccidiostats, and access to outdoor area. It is unlikely that quinolone resistance has arisen due to use of antimicrobials, since fluoroquinolones are not permitted in Swedish broiler production.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据