4.6 Review

Role of ATP-Small Heat Shock Protein Interaction in Human Diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Myopathy-associated G154S mutation causes important changes in the conformational stability, amyloidogenic properties, and chaperone-like activity of human aB-crystallin

Kazem Khoshaman et al.

Summary: This study investigated the structural and functional features of the G154S mutant alpha B-Cry protein. The mutant protein showed reduced chaperone activity, decreased conformational stability, and increased amyloid fibril formation propensity. These changes may affect the correct interaction of the mutant alpha B-Cry with its target proteins in myopathy.

BIOPHYSICAL CHEMISTRY (2022)

Review Pharmacology & Pharmacy

Apoptosis, autophagy and atherosclerosis: Relationships and the role of Hsp27

Ruiting Shan et al.

Summary: Atherosclerosis is a multifactorial chronic inflammatory disease, with Hsp27 protein playing an important role in its development by regulating apoptosis and autophagy.

PHARMACOLOGICAL RESEARCH (2021)

Review Chemistry, Physical

alpha-Crystallins in the Vertebrate Eye Lens: Complex Oligomers and Molecular Chaperones

Marc A. Sprague-Piercy et al.

Summary: Alpha-crystallins are small heat-shock proteins acting as holdase chaperones with the ability to prevent aggregation of damaged crystallins. They form dynamic, heterogeneous oligomers with central domains flanked by flexible extensions, and control oligomerization through domain swapping. Mutations or modifications can compromise their chaperone activity, leading to protein aggregation and cataract formation.

ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 72 (2021)

Article Multidisciplinary Sciences

Structural and functional studies of D109A human αB-crystallin contributing to the development of cataract and cardiomyopathy diseases

Mahtab Hafizi et al.

Summary: A new mutation in the alpha B-crystallin protein has been discovered, which can lead to myofibrillar myopathy, cataracts, and cardiomyopathy. The mutation significantly impacts the structure, stability, and chaperone-like activity of the protein.

PLOS ONE (2021)

Article Infectious Diseases

Hsp16.3 of mycobacterium tuberculosis in exosomes as a biomarker of tuberculosis

Can Huang et al.

Summary: The study found that Hsp16.3 protein overexpressed in cells can be efficiently packaged into exosomes, and cells infected with Mycobacterium tuberculosis can secrete abnormally excessive amounts of Hsp16.3 protein. Additionally, a substantial number of Hsp16.3 proteins were detected in blood exosomes of tuberculosis patients.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2021)

Article Immunology

Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

Thabatta L. S. A. Rosa et al.

Summary: Upon infection, Mycobacterium leprae induces accumulation of cholesterol in Schwann cells, which is potentially delivered to the intracellular bacterium. Cholesterol oxidation is an essential catabolic pathway for M. leprae pathogenicity, with 3 beta-HSD as a potential drug target for leprosy treatment.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Article Biochemistry & Molecular Biology

M. leprae HSP18 suppresses copper (II) mediated ROS generation: Effect of redox stress on its structure and function

Sandip Kumar Nandi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Protective effect of HSP27 in atherosclerosis and coronary heart disease by inhibiting reactive oxygen species

Hong-Li Zhang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Mitochondrial Morphofunction in Mammalian Cells

Elianne P. Bulthuis et al.

ANTIOXIDANTS & REDOX SIGNALING (2019)

Article Pharmacology & Pharmacy

Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP

Todd A. Johnson et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Medicine, Research & Experimental

The vasodilatory effect of allopurinol mediates its antihypertensive effect: Effects on calcium movement and cardiac hemodynamics

Hany M. El-Bassossy et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Biochemistry & Molecular Biology

Effects of Mycobacterium tuberculosis Mutant Strain Hsp16.3 Gene on Murine RAW 264.7 Macrophage Autophagy

Li Yang et al.

DNA AND CELL BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Insights into Macrophage Autophagy in Latent Tuberculosis Infection: Role of Heat Shock Protein 16.3

Caiqin Zhang et al.

DNA AND CELL BIOLOGY (2018)

Article Cardiac & Cardiovascular Systems

Angiotensin-(1-7) prevents atrial tachycardia induced-heat shock protein 27 expression

Xuewen Wang et al.

JOURNAL OF ELECTROCARDIOLOGY (2018)

Article Multidisciplinary Sciences

General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels

Jun-ichi Kishikawa et al.

PLOS ONE (2018)

Article Multidisciplinary Sciences

Allopurinol partially prevents disuse muscle atrophy in mice and humans

Beatriz Ferrando et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

Probing the structure-function relationship of Mycobacterium leprae HSP18 under different UV radiations

Ayon Chakraborty et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Biochemistry & Molecular Biology

Evidences for zinc (II) and copper (II) ion interactions with Mycobacterium leprae HSP18: Effect on its structure and chaperone function

Sandip Kumar Nandi et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2018)

Article Medical Laboratory Technology

Heat shock protein 27 acts as a predictor of prognosis in chronic heart failure patients

Denise Traxler et al.

CLINICA CHIMICA ACTA (2017)

Article Cardiac & Cardiovascular Systems

Safety and effect of high dose allopurinol in patients with severe left ventricular systolic dysfunction

Mohammad Mostafa Ansari-Ramandi et al.

JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH (2017)

Article Cardiac & Cardiovascular Systems

Allopurinol use and the risk of acute cardiovascular events in patients with gout and diabetes

Jasvinder A. Singh et al.

BMC CARDIOVASCULAR DISORDERS (2017)

Review Biochemistry & Molecular Biology

Differential role of arginine mutations on the structure and functions of α-crystallin

Alok Kumar Panda et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2016)

Article Biochemistry & Molecular Biology

Urat1-Uox double knockout mice are experimental animal models of renal hypouricemia and exercise-induced acute kidney injury

Makoto Hosoyamada et al.

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2016)

Article Biochemistry & Molecular Biology

Heat shock protein 20 (HSP20) is a novel substrate for protein kinase D1 (PKD1)

Yuan Yan Sin et al.

CELL BIOCHEMISTRY AND FUNCTION (2015)

Article Infectious Diseases

Interaction of ATP with a Small Heat Shock Protein from Mycobacterium leprae: Effect on Its Structure and Function

Sandip Kumar Nandi et al.

PLOS NEGLECTED TROPICAL DISEASES (2015)

Article Biochemistry & Molecular Biology

Oligomer-dependent and -independent chaperone activity of sHsps in different stressed conditions

Liang Liu et al.

FEBS OPEN BIO (2015)

Article Chemistry, Medicinal

Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials

Sara Gordon et al.

PERSPECTIVES IN MEDICINAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Alpha-crystallin-mediated protection of lens cells against heat and oxidative stress-induced cell death

Karen L. Christopher et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)

Article Medicine, Research & Experimental

α-Crystallin protects RGC survival and inhibits microglial activation after optic nerve crush

Nan Wu et al.

LIFE SCIENCES (2014)

Review Oncology

Targeting heat shock proteins in cancer

Gaetan Jego et al.

CANCER LETTERS (2013)

Article Ophthalmology

Cell Penetration Peptides for Enhanced Entry of αB-Crystallin into Lens Cells

Niklaus H. Mueller et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)

Review Chemistry, Medicinal

Anticancer Agents That Counteract Tumor Glycolysis

Carlotta Granchi et al.

CHEMMEDCHEM (2012)

Article Cell Biology

HspX-mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule

Jennifer L. Taylor et al.

IMMUNOLOGY AND CELL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Alpha-Crystallin Promotes Rat Axonal Regeneration Through Regulation of RhoA/Rock/Cofilin/MLC Signaling Pathways

Yan Hua Wang et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2012)

Review Biochemistry & Molecular Biology

Small heat shock proteins and α-crystallins: dynamic proteins with flexible functions

Eman Basha et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Article Respiratory System

Determination of levels of specific IgA to the HspX recombinant antigen of Mycobacterium tuberculosis for the diagnosis of pleural tuberculosis

Loanda Carvalho Sant' Ana Limongi et al.

JORNAL BRASILEIRO DE PNEUMOLOGIA (2011)

Article Ophthalmology

The Role of TLR4 in Photoreceptor αA Crystallin Upregulation during Early Experimental Autoimmune Uveitis

Sindhu Saraswathy et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)

Review Biochemistry & Molecular Biology

Lens aging: Effects of crystallins

K. Krishna Sharma et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)

Article Biochemistry & Molecular Biology

Human Mutation in the Anti-apoptotic Heat Shock Protein 20 Abrogates Its Cardioprotective Effects

Persoulla Nicolaou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

α-crystallin protected axons from optic nerve degeneration after crushing in rats

Xi Ying et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2008)

Review Biochemistry & Molecular Biology

Hsp27 (HspB1) and αB-crystallin (HspB5) as therapeutic targets

Andr-Patrick Arrigo et al.

FEBS LETTERS (2007)

Article Ophthalmology

A transgenic mouse model for human autosomal dominant cataract

Cheng-Da Hsu et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)

Article Biochemistry & Molecular Biology

Self-association and chaperone activity of Hsp27 are thermally activated

B Lelj-Garolla et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Medicine, Research & Experimental

alpha B-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer

JV Moyano et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Review Biochemistry & Molecular Biology

The small heat shock proteins and their role in human disease

Y Sun et al.

FEBS JOURNAL (2005)

Article Pharmacology & Pharmacy

C-terminal truncation of α-crystallin in hereditary cataractous rat lens

N Takeuchi et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2004)

Article Cardiac & Cardiovascular Systems

Roles for αB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model

LE Morrison et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)

Article Biochemistry & Molecular Biology

Carnosine disaggregates glycated α-crystallin:: an in vitro study

NW Seidler et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)

Article Pharmacology & Pharmacy

Phosphoproteome analysis of hereditary cataractous rat lens α-crystallin

A Kamei et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2004)

Article Biochemistry & Molecular Biology

Deamidation affects structural and functional properties of human αA-crystallin and its oligomerization with αB-crystallin

R Gupta et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Role of ATP on the interaction of α-crystallin with its substrates and its implications for the molecular chaperone function

A Biswas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Functional similarities between the small heat shock proteins Mycobacterium tuberculosis HSP 16.3 and human αB-crystallin

MM Valdez et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

ATP causes small heat shock proteins to release denatured protein

KY Wang et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Crystal structure and assembly of a eukaryotic small heat shock protein

RLM van Montfort et al.

NATURE STRUCTURAL BIOLOGY (2001)

Article Biochemistry & Molecular Biology

Structural and functional changes in the αA-crystallin R116C mutant in hereditary cataracts

BA Cobb et al.

BIOCHEMISTRY (2000)