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Carl Frieden et al.
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Autophagy and polyglutamine diseases
Maria Jimenez-Sanchez et al.
PROGRESS IN NEUROBIOLOGY (2012)
α-Synuclein in Parkinson's Disease
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COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Genetics of Parkinson's Disease
Christine Klein et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
N-Acetylcysteine Prevents Loss of Dopaminergic Neurons in the EAAC1-/- Mouse
Ari E. Berman et al.
ANNALS OF NEUROLOGY (2011)
Single-Cell Redox Imaging Demonstrates a Distinctive Response of Dopaminergic Neurons to Oxidative Insults
Maxx P. Horowitz et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
S-Nitrosylation of ApoE in Alzheimer's Disease
Alexander J. Abrams et al.
BIOCHEMISTRY (2011)
Kinetic, Mechanistic, and Structural Modeling Studies of Truncated Wild-Type Leucine-Rich Repeat Kinase 2 and the G2019S Mutant
Min Liu et al.
BIOCHEMISTRY (2011)
Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases
T. Nakamura et al.
CELL DEATH AND DIFFERENTIATION (2011)
The Beclin 1 network regulates autophagy and apoptosis
R. Kang et al.
CELL DEATH AND DIFFERENTIATION (2011)
The diverse functions of GAPDH: Views from different subcellular compartments
Carlos Tristan et al.
CELLULAR SIGNALLING (2011)
Disulfide bonds in ER protein folding and homeostasis
Matthias J. Feige et al.
CURRENT OPINION IN CELL BIOLOGY (2011)
Ubiquitin-proteasome pathway and cellular responses to oxidative stress
Fu Shang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane
Saori R. Yoshii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein
Jonathan H. Fox et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation
Fanjun Meng et al.
MOLECULAR NEURODEGENERATION (2011)
S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by β-amyloid peptide
Jing Qu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance
Joseph M. Castellano et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia
Walter J. Schulz-Schaeffer
ACTA NEUROPATHOLOGICA (2010)
Molecular Mechanism for H2S-Induced Activation of KATP Channels
Bo Jiang et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
Paula I. Moreira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis
Adam K. Walker et al.
BRAIN (2010)
Role of Mitochondrial Amyloid-beta in Alzheimer's Disease
John Xi Chen et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Mitochondrial Amyloid-beta Levels are Associated with the Extent of Mitochondrial Dysfunction in Different Brain Regions and the Degree of Cognitive Impairment in Alzheimer's Transgenic Mice
Natasa Dragicevic et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
The Alzheimer's Disease Mitochondrial Cascade Hypothesis
Russell H. Swerdlow et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Oxidatively Modified Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Alzheimer's Disease: Many Pathways to Neurodegeneration
D. Allan Butterfield et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Glutathionylation of Adenine Nucleotide Translocase Induced by Carbon Monoxide Prevents Mitochondrial Membrane Permeabilization and Apoptosis
Claudia S. F. Queiroga et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase
Jaroslaw W. Zmijewski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Pathogenic cysteine mutations affect progranulin function and production of mature granulins
Jun Wang et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex
Mubeen A. Ansari et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)
Protein Disulfide Isomerase and the Endoplasmic Reticulum in Amyotrophic Lateral Sclerosis
Adam K. Walker
JOURNAL OF NEUROSCIENCE (2010)
S-Nitrosylation of Cyclin-Dependent Kinase 5 (Cdk5) Regulates Its Kinase Activity and Dendrite Growth During Neuronal Development
Peng Zhang et al.
JOURNAL OF NEUROSCIENCE (2010)
Potential In Vivo Amelioration by N-Acetyl-L-Cysteine of Oxidative Stress in Brain in Human Double Mutant APP/PS-1 Knock-In Mice: Toward Therapeutic Modulation of Mild Cognitive Impairment
Quanzhen Huang et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
The Role of Parkin in Familial and Sporadic Parkinson's Disease
Ted M. Dawson et al.
MOVEMENT DISORDERS (2010)
Neural mechanisms of ageing and cognitive decline
Nicholas A. Bishop et al.
NATURE (2010)
Quantitative reactivity profiling predicts functional cysteines in proteomes
Eranthie Weerapana et al.
NATURE (2010)
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
Jaime N. Guzman et al.
NATURE (2010)
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
Marta Martinez-Vicente et al.
NATURE NEUROSCIENCE (2010)
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
Daryl A. Bosco et al.
NATURE NEUROSCIENCE (2010)
Protein palmitoylation in neuronal development and synaptic plasticity
Yuko Fukata et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
Heng Du et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1
Roman V. Kondratov et al.
AGING-US (2009)
Efficacy of a Vitamin/Nutriceutical Formulation for Moderate-stage to Later-stage Alzheimer's disease: A Placebo-controlled Pilot Study
Ruth Remington et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2009)
N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania A Double-blind, Placebo-Controlled Study
Jon E. Grant et al.
ARCHIVES OF GENERAL PSYCHIATRY (2009)
Is the oxidative stress theory of aging dead?
Viviana I. Perez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
Transthyretin: the servant of many masters
Joel N. Buxbaum et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
Hsiuchen Chen et al.
HUMAN MOLECULAR GENETICS (2009)
Redox Mechanisms Involved in the Selective Activation of Nrf2-mediated Resistance Versus p53-dependent Apoptosis in Adenocarcinoma Cells
Sara Piccirillo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structural Basis of Conserved Cysteine in the Fibroblast Growth Factor Family: Evidence for a Vestigial Half-Cystine
Jihun Lee et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin
David F. Fischer et al.
NEUROBIOLOGY OF AGING (2009)
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
Paula Desplats et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Direct and specific inactivation of protein tyrosine kinases in the Src and FGFR families by reversible cysteine oxidation
David J. Kemble et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease
Anthony H. K. Tsang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity
Srinivasa Subramaniam et al.
SCIENCE (2009)
Disulfide Formation in the ER and Mitochondria: Two Solutions to a Common Process
Jan Riemer et al.
SCIENCE (2009)
A critical reappraisal of current staging of Lewy-related pathology in human brain
Kurt A. Jellinger
ACTA NEUROPATHOLOGICA (2008)
Radical-free biology of oxidative stress
Dean P. Jones
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Amyotrophic lateral sclerosis: From current developments in the laboratory to clinical implications
Mauro Cozzolino et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Excitotoxic neuronal death and the pathogenesis of Huntington's disease
Ana Maria Estrada Sanchez et al.
ARCHIVES OF MEDICAL RESEARCH (2008)
Two distinct disulfide bonds formed in human heat shock transcription factor 1 act in opposition to regulate its DNA binding activity
Ming Lu et al.
BIOCHEMISTRY (2008)
Redox imbalance in Parkinson's disease
Shankar J. Chinta et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
Expanding the functional diversity of proteins through cysteine oxidation
Khalilah G. Reddie et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
Konstanze F. Winklhofer et al.
EMBO JOURNAL (2008)
Thiol chemistry and specificity in redox signaling
Christine C. Winterbourn et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein
He-Jin Lee et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease
Young Mook Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
High glucose oxidizes SERCA cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration
XiaoYong Tong et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis
Julie D. Atkin et al.
NEUROBIOLOGY OF DISEASE (2008)
Role of the ubiquitin proteasome system in Alzheimer's disease
Sudarshan C. Upadhya et al.
BMC BIOCHEMISTRY (2007)
S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease
Jianguo Fang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The functional role of cysteine residues for c-Abl kinase activity
Amanda Kae Leonberg et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2007)
Inhibition of acrolein-induced apoptosis by the antioxidant N-acetylcysteine
Andre Tanel et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
Pascale N. Lacor et al.
JOURNAL OF NEUROSCIENCE (2007)
High-throughput identification of catalytic redox-active cysteine residues
Dmitri E. Fomenko et al.
SCIENCE (2007)
Lipoic acid and n-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts
Paula I. Moreira et al.
JOURNAL OF ALZHEIMERS DISEASE (2007)
Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store
Olivier Thibault et al.
AGING CELL (2007)
Inhibitors of NF-κB signaling:: 785 and counting
T. D. Gilmore et al.
ONCOGENE (2006)
Contribution of presenilin transmembrane domains 6 and 7 to a water-containing cavity in the γ-secretase complex
Alexandra Tolia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
Latha Devi et al.
JOURNAL OF NEUROSCIENCE (2006)
Redox regulation of cardiac calcium channels and transporters
Aleksey V. Zima et al.
CARDIOVASCULAR RESEARCH (2006)
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis
Rukhsana Sultana et al.
NEUROBIOLOGY OF AGING (2006)
Protein degradation by the ubiquitin-proteasome pathway in normal and disease states
Stewart H. Lecker et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Mitochondria: Dynamic organelles in disease, aging, and development
David C. Chan
CELL (2006)
Deducing the transmembrane domain organization of presenilin-1 in γ-secretase by cysteine disulfide cross-linking
Anna Y. Kornilova et al.
BIOCHEMISTRY (2006)
S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
Takashi Uehara et al.
NATURE (2006)
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice
Grace E. Stutzmann et al.
JOURNAL OF NEUROSCIENCE (2006)
A specific amyloid-β protein assembly in the brain impairs memory
S Lesné et al.
NATURE (2006)
Quantitative mapping of oxidation-sensitive cysteine residues in SERCA in vivo and in vitro by HPLC-electrospray-tandem MS:: selective protein oxidation during biological aging
VS Sharov et al.
BIOCHEMICAL JOURNAL (2006)
Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1
G Ito et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
K Aoyama et al.
NATURE NEUROSCIENCE (2006)
α-synuclein cooperates with CSPα in preventing neurodegeneration
S Chandra et al.
CELL (2005)
A nine-transmembrane domain topology for presenilin 1
H Laudon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Co-administration of N-acetylcysteine, vitamin B12 and folate in cognitively impaired hyperhomocysteinaemic patients
A McCaddon et al.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2005)
Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels
MV Avshalumov et al.
JOURNAL OF NEUROSCIENCE (2005)
Mitochondria, oxidants, and aging
RS Balaban et al.
CELL (2005)
The oxidative environment and protein damage
MJ Davies
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)
The efficiency of protein compartmentalization into the secretory pathway
CG Levine et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
α-synuclein and Parkinson's Disease
A Recchia et al.
FASEB JOURNAL (2004)
Tyrosine-to-cysteine modification of human α-synuclein enhances protein aggregation and cellular toxicity
WB Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation
JH Fox et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Cysteine oxidation of tau and microtubule-associated protein-2 by peroxynitrite - Modulation of microtubule assembly kinetics by the thioredoxin reductase system
LM Landino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nitrosative stress linked to sporadic Parkinson's disease:: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
DD Yao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
A Zimprich et al.
NEURON (2004)
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
RM Canet-Avilés et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cytochrome c oxidase is decreased in Alzheimer's disease platelets
SM Cardoso et al.
NEUROBIOLOGY OF AGING (2004)
Structure of membrane-bound α-synuclein studied by site-directed spin labeling
CC Jao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge - Relevance to age-related neurodegeneration
F Tchantchou et al.
NEUROMOLECULAR MEDICINE (2004)
Palmitoylation of intracellular signaling proteins: Regulation and function
JE Smotrys et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
The role of oxidative damage and stress in aging
A Bokov et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2004)
Quality control in the endoplasmic reticulum protein factory
R Sitia et al.
NATURE (2003)
Antioxidant N-acetylcysteine DNQX inhibited mixed lineage and AMPA/KA receptor antagonist kinase-3 activation following cerebral ischemia in rat hippocampus
H Tian et al.
NEUROSCIENCE RESEARCH (2003)
Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine
S Beretta et al.
NEUROBIOLOGY OF DISEASE (2003)
The adenine nucleotide translocase: A central component of the mitochondrial permeability transition pore and key player in cell death
AP Halestrap et al.
CURRENT MEDICINAL CHEMISTRY (2003)
X-ray structure of human acid-β-glucosidase, the defective enzyme in Gaucher disease
H Dvir et al.
EMBO REPORTS (2003)
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain - A regulator of neuronal copper homeostasis
KJ Barnham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Nitric oxide, NOC-12, and S-nitrosoglutathione modulate the skeletal muscle calcium release channel/ryanodine receptor by different mechanisms -: An allosteric function for O2 in S-nitrosylation of the channel
JH Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The antioxidants α-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice
SA Farr et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
V Bonifati et al.
SCIENCE (2003)
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation
N Benaroudj et al.
MOLECULAR CELL (2003)
Identification of new presenilin gene mutations in early-onset familial Alzheimer disease
A Tedde et al.
ARCHIVES OF NEUROLOGY (2003)
Oxidative stress in Parkinson's disease
P Jenner
ANNALS OF NEUROLOGY (2003)
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
DD Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Plasma membrane monoamine transporters: Structure, regulation and function
GE Torres et al.
NATURE REVIEWS NEUROSCIENCE (2003)
Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor alpha, dopamine and beta-amyloid peptide 1-42
S Medina et al.
FREE RADICAL RESEARCH (2002)
Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses
DP Jones et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism
WZ Duan et al.
ANNALS OF NEUROLOGY (2002)
Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2
KR Sekhar et al.
ONCOGENE (2002)
Lipid peroxidation in aging brain and Alzheimer's disease
TJ Montine et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior
MP Mattson et al.
PHYSIOLOGICAL REVIEWS (2002)
IAP proteins: Blocking the road to death's door
GS Salvesen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Endogenous oxidative stress: relationship to aging, longevity and caloric restriction
G Barja
AGEING RESEARCH REVIEWS (2002)
Hassles with taking out the garbage: Aggravating aggresomes
R Garcia-Mata et al.
TRAFFIC (2002)
Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease
F Bosetti et al.
NEUROBIOLOGY OF AGING (2002)
A Ca2+ switch aligns the active site of calpain
T Moldoveanu et al.
CELL (2002)
Synaptotagmins:: Why so many?
TC Südhof
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Glutathione decreases in dopaminergic PC 12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?
N Jha et al.
JOURNAL OF NEUROCHEMISTRY (2002)
N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: effects on beta-amyloid secretion and tau phosphorylation
G Olivieri et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
AJ García-Piñeres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Controlled trial of N-acetyleysteine for patients with probable Alzheimer's disease
JC Adair et al.
NEUROLOGY (2001)
Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins
DA Butterfield et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2001)
Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points
S De Flora et al.
CARCINOGENESIS (2001)
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
K Fassbender et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases
MM Banaclocha
MEDICAL HYPOTHESES (2001)
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β-peptide
C Culmsee et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Role for cysteine residues in the in vivo folding and assembly of the phage P22 tailspike
C Haase-Pettingell et al.
PROTEIN SCIENCE (2001)
N-acetyl-L-cystein downregulates ss-amyloid precursor protein gene transcription in human neuroblastoma cells
R Studer et al.
BIOGERONTOLOGY (2001)
N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis
OA Andreassen et al.
NEUROREPORT (2000)
Beneficial effects of dietary restriction on cerebral cortical synaptic terminals:: Preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid β-peptide, iron, and 3-nitropropionic acid
ZH Guo et al.
JOURNAL OF NEUROCHEMISTRY (2000)
N-Acetylcysteine elicited increase in complex I activity in synaptic mitochondria from aged mice:: implications for treatment of Parkinson's disease
MM Banaclocha
BRAIN RESEARCH (2000)
A mechanism for the neuroprotective effect of apolipoprotein E: Isoform-specific modification by the lipid peroxidation product 4-hydroxynonenal
WA Pedersen et al.
JOURNAL OF NEUROCHEMISTRY (2000)
N-Acetylcysteine delays age-associated memory impairment in mice:: role in synaptic mitochondria
M Martínez et al.
BRAIN RESEARCH (2000)
Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter
NH Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Common gene variants, mortality and extreme longevity in humans
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EXPERIMENTAL GERONTOLOGY (2000)
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