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AMPKα2 counteracts the development of cardiac hypertrophy induced by isoproterenol
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Is the combination of sulfonylureas and metformin associated with an increased risk of cardiovascular disease or all-cause mortality? A meta-analysis of observational studies
Ajay D. Rao et al.
DIABETES CARE (2008)
Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure
Michael R. MacDonald et al.
EUROPEAN HEART JOURNAL (2008)
The risk of heart failure in patients with type 2 diabetes treated with oral agent monotherapy
Finlay A. McAlister et al.
EUROPEAN JOURNAL OF HEART FAILURE (2008)
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
Anushka Patel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Effects of intensive glucose lowering in type 2 diabetes
Hertzel C. Gerstein et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
10-year follow-up of intensive glucose control in type 2 diabetes
Rury R. Holman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: A report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)
Barry H. Greenberg et al.
AMERICAN HEART JOURNAL (2007)
Apoptosis in patients with dilated cardiornyopathy and diabetes: A feature of diabetic cardiomyopathy?
F. Kuethe et al.
HORMONE AND METABOLIC RESEARCH (2007)
Mechanisms of disease - The failing heart - An engine out of fuel
Stefan Neubauer
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy - A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes
D. M. Nathan et al.
DIABETOLOGIA (2006)
AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
L Bertrand et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Metformin inhibits proinflammatory responses and nuclear factor-κB in human vascular wall cells
K Isoda et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase
BJ Davis et al.
DIABETES (2006)
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
RJ Shaw et al.
SCIENCE (2005)
Improved clinical outcomes associated with metformin in patients with diabetes and heart failure
DT Eurich et al.
DIABETES CARE (2005)
Impaired insulin sensitivity as an independent risk factor for mortality in patients with stable chronic heart failure
W Doehner et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)
Cardiomyocyte stiffness in Diastolic heart failure
A Borbély et al.
CIRCULATION (2005)
Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure - An observational study
FA Masoudi et al.
CIRCULATION (2005)
The incidence of congestive heart failure associated with antidiabetic therapies
GA Nichols et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2005)
Determinants of subclinical diabetic heart disease
ZY Fang et al.
DIABETOLOGIA (2005)
Influence of diabetes and diabetes-gender interaction on the risk of death in patients hospitalized with congestive heart failure
I Gustafsson et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Heart failure prevalence, incidence, and mortality in the elderly with diabetes
AG Bertoni et al.
DIABETES CARE (2004)
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte
AYM Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The effect of metformin on blood pressure, plasma cholesterol and triglycerides in type 2 diabetes mellitus:: a systematic review
MG Wulffelé et al.
JOURNAL OF INTERNAL MEDICINE (2004)
Modulation of NOS activity in age-related cardiac dysfunction
B Yang et al.
LIFE SCIENCES (2004)
Mechanisms for increased glycolysis in the hypertrophied rat heart
L Nascimben et al.
HYPERTENSION (2004)
The AMP-activated protein kinase pathway - new players upstream and downstream
DG Hardie
JOURNAL OF CELL SCIENCE (2004)
Excess mortality related to diabetes mellitus in elderly medicare beneficiaries
AG Bertoni et al.
ANNALS OF EPIDEMIOLOGY (2004)
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus - Systematic review and meta-analysis
SR Salpeter et al.
ARCHIVES OF INTERNAL MEDICINE (2003)
Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis
A Woods et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling.
DR Bolster et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Intracerebroventricular metformin attenuates salt-induced hypertension in spontaneously hypertensive rats
JS Petersen et al.
AMERICAN JOURNAL OF HYPERTENSION (2001)
Congestive heart failure in type 2 diabetes - Prevalence, incidence, and risk factors
GA Nichols et al.
DIABETES CARE (2001)
Mutations in the γ2 subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy:: evidence for the central role of energy compromise in disease pathogenesis
E Blair et al.
HUMAN MOLECULAR GENETICS (2001)
The effects of β1-blockade on oxidative metabolism and the metabolic cost of ventricular work in patients with left ventricular dysfunction -: A double-blind, placebo-controlled, positron-emission tomography study
RSB Beanlands et al.
CIRCULATION (2000)