期刊
BIOMOLECULES
卷 11, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/biom11121874
关键词
black cumin seed essential oil; deodorant activity; garlic organosulfur compounds; Nigella sativa L
The study evaluated the deodorant activity of black cumin seed against organosulfur compounds related to garlic odor, finding that black cumin seed essential oil showed remarkable deodorant activity against garlic essential oil, presumably by covalently reacting with the sulfur compounds. This reaction, particularly with thymoquinone and allyl mercaptan, was identified as a key factor in the deodorizing effect.
The deodorant activity of black cumin (Nigella sativa L.) seed, a spice used to flavor curry and vegetable foods in Southwest Asia, against garlic (Allium sativum L.) organosulfur compounds related to human malodor was evaluated. Black cumin seed essential oil showed remarkable deodorant activity against garlic essential oil. The mode of action of this deodorant activity was presumed to be that black cumin seed essential oil covalently reacted with the organosulfur compounds in garlic. Therefore, thymoquinone, which is a major constituent in black cumin seed essential oil, and allyl mercaptan, which is one of the organosulfur compounds produced by cutting garlic, were reacted in vitro, and the products were purified and elucidated using spectroscopic data. As a result, these substances were identified as different allyl mercaptan adducts to dihydrothymoquinone. This chemical reaction was presumed to play a key role in the deodorant activity of black cumin seed essential oil.
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