相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。MYC Upregulation Confers Resistance to Everolimus and Establishes Vulnerability to Cyclin-Dependent Kinase Inhibitors in Pancreatic Neuroendocrine Neoplasm Cells
Francesca Terracciano et al.
NEUROENDOCRINOLOGY (2021)
Heat Stress Responses and Thermotolerance in Maize
Zhaoxia Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Proteomic approaches for the profiling of ubiquitylation events and their applications in drug discovery
Zhanhong Hu et al.
JOURNAL OF PROTEOMICS (2021)
RNA-binding proteins in human genetic disease
Fatima Gebauer et al.
NATURE REVIEWS GENETICS (2021)
Communicating clocks shape circadian homeostasis
Kevin B. Koronowski et al.
SCIENCE (2021)
Reciprocal Links between Pre-messenger RNA 3′-End Processing and Genome Stability
Martin Dutertre et al.
TRENDS IN BIOCHEMICAL SCIENCES (2021)
Translating around the clock: Multi-level regulation of post-transcriptional processes by the circadian clock
Amber A. Parnell et al.
CELLULAR SIGNALLING (2021)
Ubiquitin-dependent regulation of transcription in development and disease
Kevin G. Mark et al.
EMBO REPORTS (2021)
The transcription factor code: a beacon for histone methyltransferase docking
Guillem Torcal Garcia et al.
TRENDS IN CELL BIOLOGY (2021)
Oncogenic dysregulation of pre-mRNA processing by protein kinases: challenges and therapeutic opportunities
Chiara Naro et al.
FEBS JOURNAL (2021)
SUMOylation Regulates TDP-43 Splicing Activity and Nucleocytoplasmic Distribution
AnnaMaria Maraschi et al.
MOLECULAR NEUROBIOLOGY (2021)
KRAS4A induces metastatic lung adenocarcinomas in vivo in the absence of the KRAS4B isoform
Marina Salmon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells
Wei-Ching Chen et al.
NATURE COMMUNICATIONS (2021)
Light regulates alternative splicing outcomes via the TOR kinase pathway
Stefan Riegler et al.
CELL REPORTS (2021)
Targeting mRNA processing as an anticancer strategy
Joana Desterro et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Molecular mechanisms and physiological importance of circadian rhythms
Alina Patke et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair
Yuka Nakazawa et al.
CELL (2020)
The circadian clock shapes the Arabidopsis transcriptome by regulating alternative splicing and alternative polyadenylation
Yuchen Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
The expanding regulatory mechanisms and cellular functions of circular RNAs
Ling-Ling Chen
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
Luisa F. Escobar-Hoyos et al.
CANCER CELL (2020)
Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS
Alexandra Arenas et al.
HUMAN MOLECULAR GENETICS (2020)
A large-scale binding and functional map of human RNA-binding proteins
Eric L. Van Nostrand et al.
NATURE (2020)
ERK signalling: a master regulator of cell behaviour, life and fate
Hugo Lavoie et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Global view of human protein glycosylation pathways and functions
Katrine T. Schjoldager et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation
Marc A. J. Morgan et al.
NATURE GENETICS (2020)
Phosphorylation and Circadian Molecular Timing
Andrea Brenna et al.
FRONTIERS IN PHYSIOLOGY (2020)
Metabolic rivalry: circadian homeostasis and tumorigenesis
Kenichiro Kinouchi et al.
NATURE REVIEWS CANCER (2020)
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma
Hongfa Xu et al.
THERANOSTICS (2020)
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins
Yongjia Duan et al.
CELL RESEARCH (2019)
PTEN arginine methylation by PRMT6 suppresses PI3K-AKT signaling and modulates pre-mRNA splicing
Jiawen Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Post-Translational Modification, Phase Separation, and Robust Gene Transcription
Hari R. Singh et al.
TRENDS IN GENETICS (2019)
Structural Insights into Nuclear p e-mRNA Splicing in Higher Eukaryotes
Berthold Kastner et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)
Functional Interaction between U1snRNP and Sam68 Insures Proper 3′ End Pre-mRNA Processing during Germ Cell Differentiation
Chiara Naro et al.
CELL REPORTS (2019)
Post-translational modification control of RNA-binding protein hnRNPK function
Yongjie Xu et al.
OPEN BIOLOGY (2019)
Regulation of alternative splicing by p300-mediated acetylation of splicing factors
Ahmad Siam et al.
RNA (2019)
More than a messenger: Alternative splicing as a therapeutic target
A. J. Black et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2019)
Defining the Independence of the Liver Circadian Clock
Kevin B. Koronowski et al.
CELL (2019)
Alternative cleavage and polyadenylation in health and disease
Andreas J. Gruber et al.
NATURE REVIEWS GENETICS (2019)
The regulation, functions and clinical relevance of arginine methylation
Ernesto Guccione et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses
Lei Wang et al.
SCIENCE (2019)
Circadian clock genes and the transcriptional architecture of the clock mechanism
Kimberly H. Cox et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2019)
The DNA damage response to transcription stress
Hannes Lans et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution
Jernej Ule et al.
MOLECULAR CELL (2019)
O-GlcNAc-induced nuclear translocation of hnRNP-K is associated with progression and metastasis of cholangiocarcinoma
Chatchai Phoomak et al.
MOLECULAR ONCOLOGY (2019)
Crosstalk between metabolism and circadian clocks
Hans Reinke et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Mitochondrial Heat Shock Protein 60s Interact with What's This Factor 9 to Regulate RNA Splicing of ccmFC and rpl2
Ya-Wen Hsu et al.
PLANT AND CELL PHYSIOLOGY (2019)
Genotoxic stress causes the accumulation of DNA-dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre-mRNA alternative splicing
Shuang Liu et al.
FEBS OPEN BIO (2019)
mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response
Danae Fonseca et al.
MOLECULAR AND CELLULAR BIOLOGY (2018)
Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
Michal Gavish-Izakson et al.
NUCLEIC ACIDS RESEARCH (2018)
Mobilization of a splicing factor through a nuclear kinase-kinase complex
Brandon E. Aubol et al.
BIOCHEMICAL JOURNAL (2018)
Maintenance of genome stability: the unifying role of interconnections between the DNA damage response and RNA-processing pathways
B. Mikolaskova et al.
CURRENT GENETICS (2018)
TDP-43 post-translational modifications in health and disease
Emanuele Buratti
EXPERT OPINION ON THERAPEUTIC TARGETS (2018)
Generation of circadian rhythms in the suprachiasmatic nucleus
Michael H. Hastings et al.
NATURE REVIEWS NEUROSCIENCE (2018)
Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells
Trees-Juen Chuang et al.
NUCLEIC ACIDS RESEARCH (2018)
When SUMO met splicing
Berta Pozzi et al.
RNA BIOLOGY (2018)
Regulatory Potential of the RNA Processing Machinery: Implications for Human Disease
Kirstyn T. Carey et al.
TRENDS IN GENETICS (2018)
DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components
A. Pascarella et al.
SCIENTIFIC REPORTS (2018)
Circadian processes in the RNA life cycle
Manon Torres et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2018)
Protein palmitoylation and cancer
Pin-Joe Ko et al.
EMBO REPORTS (2018)
CBP-mediated SMN acetylation modulates Cajal body biogenesis and the cytoplasmic targeting of SMN
Vanesa Lafarga et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Alternative polyadenylation of mRNA precursors
Bin Tian et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach
Suman Chatterjee et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
The G-Quadruplex-Specific RNA Helicase DHX36 Regulates p53 Pre-mRNA 3′-End Processing Following UV-Induced DNA Damage
Michelle Newman et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
Arginine Methylation: The Coming of Age
Romeo S. Blanc et al.
MOLECULAR CELL (2017)
Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals
Marco Preussner et al.
MOLECULAR CELL (2017)
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
Andrew N. Blackford et al.
MOLECULAR CELL (2017)
Nusinersen, an antisense oligonucleotide drug for spinal muscular atrophy
David R. Corey
NATURE NEUROSCIENCE (2017)
hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells
Ilaria Passacantilli et al.
NUCLEIC ACIDS RESEARCH (2017)
USP15 regulates dynamic protein-protein interactions of the spliceosome through deubiquitination of PRP31
Tanuza Das et al.
NUCLEIC ACIDS RESEARCH (2017)
SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing
Berta Pozzi et al.
NUCLEIC ACIDS RESEARCH (2017)
Phosphorylation: Implications in Cancer
Vishakha Singh et al.
PROTEIN JOURNAL (2017)
Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation
Manuel J. Munoz et al.
CELL REPORTS (2017)
Insulin regulates titin pre-mRNA splicing through the PI3K-Akt-mTOR kinase axis in a RBM20-dependent manner
Chaoqun Zhu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
SUMO and the robustness of cancer
Jacob-Sebastian Seeler et al.
NATURE REVIEWS CANCER (2017)
UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene
Laura Williamson et al.
CELL (2017)
NCLscan: accurate identification of non-co-linear transcripts (fusion, trans-splicing and circular RNA) with a good balance between sensitivity and precision
Trees-Juen Chuang et al.
NUCLEIC ACIDS RESEARCH (2016)
Alternative splicing and cell survival: from tissue homeostasis to disease
Maria Paola Paronetto et al.
CELL DEATH AND DIFFERENTIATION (2016)
Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing
Brandon E. Aubol et al.
MOLECULAR CELL (2016)
A comprehensive compilation of SUMO proteomics
Ivo A. Hendriks et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
The intricate dance of post-translational modifications in the rhythm of life
Arisa Hirano et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis
Xin Zhang et al.
NUCLEIC ACIDS RESEARCH (2016)
Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut
Nick J. Proudfoot
SCIENCE (2016)
The Spliceosome: The Ultimate RNA Chaperone anc Sculptor
Panagiotis Papasaikas et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
The intricate dance of post-translational modifications in the rhythm of life
Arisa Hirano et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors
Lulzim Shkreta et al.
CELL REPORTS (2016)
CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer
Shawn F. Johnson et al.
CELL REPORTS (2016)
Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating AIdh1a3 pre-mRNA 3′-end processing
Piergiorgio La Rosa et al.
eLife (2016)
SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies
Ya-Chen Liang et al.
SCIENTIFIC REPORTS (2016)
Regulation of Alternative Splicing Through Coupling with Transcription and Chromatin Structure
Shiran Naftelberg et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
Mechanisms and Regulation of Alternative Pre-mRNA Splicing
Yeon Lee et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
Flowering time regulation in crops - what did we learn from Arabidopsis?
Martina Bluemel et al.
CURRENT OPINION IN BIOTECHNOLOGY (2015)
Circadian Clock Genes Universally Control Key Agricultural Traits
Claire Bendix et al.
MOLECULAR PLANT (2015)
The core spliceosome as target and effector of non-canonical ATM signalling
Maria Tresini et al.
NATURE (2015)
Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage
Daniel F. Comiskey et al.
NUCLEIC ACIDS RESEARCH (2015)
Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68
Kiran Kumar Nakka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Systematic Profiling of Poly(A) plus Transcripts Modulated by Core 3′ End Processing and Splicing Factors Reveals Regulatory Rules of Alternative Cleavage and Polyadenylation
Wencheng Li et al.
PLOS GENETICS (2015)
SAM68: Signal Transduction and RNA Metabolism in Human Cancer
Paola Frisone et al.
BIOMED RESEARCH INTERNATIONAL (2015)
The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability
Chiara Naro et al.
FRONTIERS IN GENETICS (2015)
The RNAissance family: SR proteins as multifaceted regulators of gene expression
Jonathan M. Howard et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2015)
A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II
Saskia Hutten et al.
JOURNAL OF CELL SCIENCE (2014)
The Functional Landscape of Hsp27 Reveals New Cellular Processes such as DNA Repair and Alternative Splicing and Proposes Novel Anticancer Targets
Maria Katsogiannou et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
HuR Regulates Alternative Splicing of the TRA2β Gene in Human Colon Cancer Cells under Oxidative Stress
Yoko Akaike et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
N-myristoylation regulates the axonal distribution of the Fragile X-related protein FXR2P
Emily E. Stackpole et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2014)
Phosphoproteomics Screen Reveals Akt Isoform-Specific Signals Linking RNA Processing to Lung Cancer
Ioannis Sanidas et al.
MOLECULAR CELL (2014)
Rhythmic U2af26 Alternative Splicing Controls PERIOD1 Stability and the Circadian Clock in Mice
Marco Preussner et al.
MOLECULAR CELL (2014)
Context-dependent control of alternative splicing by RNA-binding proteins
Xiang-Dong Fu et al.
NATURE REVIEWS GENETICS (2014)
The growing landscape of lysine acetylation links metabolism and cell signalling
Chunaram Choudhary et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Arginine methylation of hnRNPK negatively modulates apoptosis upon DNA damage through local regulation of phosphorylation
Jen-Hao Yang et al.
NUCLEIC ACIDS RESEARCH (2014)
Regulation of transcription factor activity by interconnected post-translational modifications
Theresa M. Filtz et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration
Rajarshi Choudhury et al.
NATURE COMMUNICATIONS (2014)
Widespread Inhibition of Posttranscriptional Splicing Shapes the Cellular Transcriptome following Heat Shock
Reut Shalgi et al.
CELL REPORTS (2014)
ATM-dependent phosphorylation of heterogeneous nuclear ribonucleoprotein K promotes p53 transcriptional activation in response to DNA damage
Abdeladim Moumen et al.
CELL CYCLE (2013)
Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle
Guillermo Risso et al.
CELL CYCLE (2013)
Central control of peripheral circadian oscillators
Michael Menaker et al.
CURRENT OPINION IN NEUROBIOLOGY (2013)
Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery
Marco Bezzi et al.
GENES & DEVELOPMENT (2013)
hnRNP U Enhances Caspase-9 Splicing and Is Modulated by AKT-dependent Phosphorylation of hnRNP L
Ngoc T. Vu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Alternative cleavage and polyadenylation: extent, regulation and function
Ran Elkon et al.
NATURE REVIEWS GENETICS (2013)
Gemcitabine triggers a pro-survival response in pancreatic cancer cells through activation of the MNK2/eIF4E pathway
L. Adesso et al.
ONCOGENE (2013)
An Autoregulatory Loop Controlling Arabidopsis HsfA2 Expression: Role of Heat Shock-Induced Alternative Splicing1[C]
Jinjie Liu et al.
PLANT PHYSIOLOGY (2013)
Cold-induced RNA-binding proteins regulate circadian gene expression by controlling alternative polyadenylation
Yuting Liu et al.
SCIENTIFIC REPORTS (2013)
The RNA polymerase II CTD coordinates transcription and RNA processing
Jing-Ping Hsin et al.
GENES & DEVELOPMENT (2012)
Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression
Shihoko Kojima et al.
GENES & DEVELOPMENT (2012)
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
Miranda L. Tradewell et al.
HUMAN MOLECULAR GENETICS (2012)
DNA Damage-induced Heterogeneous Nuclear Ribonucleoprotein K SUMOylation Regulates p53 Transcriptional Activation
Federico Pelisch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The mRNA-stabilizing Factor HuR Protein Is Targeted by β-TrCP Protein for Degradation in Response to Glycolysis Inhibition
Po-Chen Chu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Protein arginine methylation of SERBP1 by protein arginine methyltransferase 1 affects cytoplasmic/nuclear distribution
Yu-Jen Lee et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2012)
Mitogen-Activated Protein Kinase Phosphorylation of Splicing Factor 45 (SPF45) Regulates SPF45 Alternative Splicing Site Utilization, Proliferation, and Cell Adhesion
Adnan M. Al-Ayoubi et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
An Acetylation Switch Regulates SUMO-Dependent Protein Interaction Networks
Rebecca Ullmann et al.
MOLECULAR CELL (2012)
The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus
Zhihong Zhou et al.
MOLECULAR CELL (2012)
Site-specific DICER and DROSHA RNA products control the DNA-damage response
Sofia Francia et al.
NATURE (2012)
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
Wei Guo et al.
NATURE MEDICINE (2012)
Phosphorylation of SRSF1 is modulated by replicational stress
Valentina Leva et al.
NUCLEIC ACIDS RESEARCH (2012)
Regulation of alternative splicing by the circadian clock and food related cues
Nicholas J. McGlincy et al.
GENOME BIOLOGY (2012)
Identification of the methylation preference region in heterogeneous nuclear ribonucleoprotein K by protein arginine methyltransferase 1 and its implication in regulating nuclear/cytoplasmic distribution
Yuan-I Chang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1
Takatoshi Iijima et al.
CELL (2011)
Epigenetics in Alternative Pre-mRNA Splicing
Reini F. Luco et al.
CELL (2011)
Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation
Kiyoshi Masuda et al.
EMBO JOURNAL (2011)
Essential role for the interaction between hnRNP H/F and a G quadruplex in maintaining p53 pre-mRNA 3′-end processing and function during DNA damage
Adrien Decorsiere et al.
GENES & DEVELOPMENT (2011)
The DNA Damage Response Pathway Regulates the Alternative Splicing of the Apoptotic Mediator Bcl-x
Lulzim Shkreta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The Ewing Sarcoma Protein Regulates DNA Damage-Induced Alternative Splicing
Maria Paola Paronetto et al.
MOLECULAR CELL (2011)
Mechanisms and Consequences of Alternative Polyadenylation
Dafne Campigli Di Giammartino et al.
MOLECULAR CELL (2011)
Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR
Svetlana Lebedeva et al.
MOLECULAR CELL (2011)
Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function
Ting-Xi Yu et al.
NUCLEIC ACIDS RESEARCH (2011)
Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements
Felizza Q. Gunderson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Alternative Splicing of the Cyclin D1 Proto-Oncogene Is Regulated by the RNA-Binding Protein Sam68
Maria Paola Paronetto et al.
CANCER RESEARCH (2010)
Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a
Jacqueline C. Shultz et al.
CANCER RESEARCH (2010)
Modification at HuR(S242) alters HuR localization and proliferative influence
Hyeon Ho Kim et al.
CELL CYCLE (2010)
The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy
Simona Pedrotti et al.
EMBO JOURNAL (2010)
Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway
Eric S. White et al.
EXPERIMENTAL CELL RESEARCH (2010)
The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome
Eun Joo Song et al.
GENES & DEVELOPMENT (2010)
Genome-wide mapping of alternative splicing in Arabidopsis thaliana
Sergei A. Filichkin et al.
GENOME RESEARCH (2010)
Sam68 regulates EMT through alternative splicing-activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene
Cristina Valacca et al.
JOURNAL OF CELL BIOLOGY (2010)
Protein Arginine Methylation Facilitates Cotranscriptional Recruitment of Pre-mRNA Splicing Factors
Yin-Chu Chen et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Arginine Methylation Controls the Subcellular Localization and Functions of the Oncoprotein Splicing Factor SF2/ASF
Rahul Sinha et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
A methyl transferase links the circadian clock to the regulation of alternative splicing
Sabrina E. Sanchez et al.
NATURE (2010)
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
Jaclyn R. Gareau et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Cotranscriptional exon skipping in the genotoxic stress response
Martin Dutertre et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin
Roberta Busa et al.
NUCLEIC ACIDS RESEARCH (2010)
Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing
Xian Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Regulation of Alternative Splicing by Histone Modifications
Reini F. Luco et al.
SCIENCE (2010)
DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation
Manuel J. Munoz et al.
CELL (2009)
Akt2 Regulation of Cdc2-Like Kinases (Clk/Sty), Serine/Arginine-Rich (SR) Protein Phosphorylation, and Insulin-Induced Alternative Splicing of PKCβII Messenger Ribonucleic Acid
Kun Jiang et al.
ENDOCRINOLOGY (2009)
Interaction of Akt-phosphorylated SRPK2 with 14-3-3 Mediates Cell Cycle and Cell Death in Neurons
Sung-Wuk Jang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis
Maria Paola Paronetto et al.
JOURNAL OF CELL BIOLOGY (2009)
Nonproteolytic Functions of Ubiquitin in Cell Signaling
Zhijian J. Chen et al.
MOLECULAR CELL (2009)
Ubiquitin-binding domains - from structures to functions
Ivan Dikic et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Identification of a physiological E2 module for the human anaphase-promoting complex
Adam Williamson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation
Andreas N. Kuhn et al.
RNA (2009)
Acetylation by the Transcriptional Coactivator Gcn5 Plays a Novel Role in Co-Transcriptional Spliceosome Assembly
Felizza Q. Gunderson et al.
PLOS GENETICS (2009)
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex
Lingyan Jin et al.
CELL (2008)
Arginine methylation of hnRNP K enhances p53 transcriptional activity
Yibin Chen et al.
FEBS LETTERS (2008)
A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation
Yu-yi Lin et al.
GENES & DEVELOPMENT (2008)
SUMO-1 transiently localizes to Cajal bodies in mammalian neurons
J. Navascues et al.
JOURNAL OF STRUCTURAL BIOLOGY (2008)
A role for ubiquitin in the spliceosome assembly pathway
Priya Bellare et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome
Rebecca Mathew et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
PI3K/Akt: getting it right matters
T. F. Franke
ONCOGENE (2008)
Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing
Tatyana Novoyatleva et al.
HUMAN MOLECULAR GENETICS (2008)
Sumoylation modulates the assembly and activity of the pre-mRNA 3′ processing complex
Vasupradha Vethantham et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
Sean D. Taverna et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
A complex signaling pathway regulates SRp38 phosphorylation and Pre-mRNA splicing in response to heat shock
Yongsheng Shi et al.
MOLECULAR CELL (2007)
Mechanisms of specificity in protein phosphorylation (vol 8, pg 530, 2007)
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Mechanisms of specificity in protein phosphorylation
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
Immediate early response of the circadian polyA ribonuclease nocturnin to two extracellular stimuli
Eduardo Garbarino-Pico et al.
RNA (2007)
Physiological roles of PKB/Akt isoforms in development and disease
B. Dummler et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x
Maria Paola Paronetto et al.
JOURNAL OF CELL BIOLOGY (2007)
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
Kotb Abdelmohsen et al.
MOLECULAR CELL (2007)
PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins
Yongsheng Shi et al.
MOLECULAR CELL (2006)
The methylation of the C-terminal region of hnRNPQ (NSAP1) is important for its nuclear localization
Dario O. Passos et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
A positive feedback loop couples Ras activation and CD44 alternative splicing
Chonghui Cheng et al.
GENES & DEVELOPMENT (2006)
Asymmetric arginine dimethylation of heterogeneous nuclear ribonucleoprotein K by protein-arginine methyltransferase 1 inhibits its interaction with c-Src
A Ostareck-Lederer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p
P Bellare et al.
RNA (2006)
Regulation of CD44 alternative splicing by SRm160 and its potential role in tumor cell invasion
CH Cheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The human SWI/SNF subunit Brm is a regulator of alternative splicing
E Batsche et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
hnRNP K: An HDM2 target and transcriptional coactivator of p53 in response to DNA damage
A Moumen et al.
CELL (2005)
Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT
M Blaustein et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Tyrosine phosphorylation of Sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression
KE Lukong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Akt-mediated phsophorylationof EZH2 suppresses methylation of lysine 27 in histone H3
TL Cha et al.
SCIENCE (2005)
Building specificity with nonspecific RNA-binding proteins
R Singh et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Circadian rhythms from multiple oscillators: Lessons from diverse organisms
D Bell-Pedersen et al.
NATURE REVIEWS GENETICS (2005)
Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CβII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40
NA Patel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A key role for stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules
A Metz et al.
JOURNAL OF CELL SCIENCE (2004)
Control of mRNA translation and stability in haematopoietic cells: The function of hnRNPs K and E1/E2
A Ostareck-Lederer et al.
BIOLOGY OF THE CELL (2004)
Ubiquitin-like protein hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast
CRM Wilkinson et al.
CURRENT BIOLOGY (2004)
Mechanism and function of deubiquitinating enzymes
AY Amerik et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner
SS Zhang et al.
NUCLEIC ACIDS RESEARCH (2004)
The RNA binding protein Sam68 is acetylated in tumor cell lines, and its acetylation correlates with enhanced RNA binding activity
I Babic et al.
ONCOGENE (2004)
Why do cells need an assembly machine for RNA-protein complexes?
JS Yong et al.
TRENDS IN CELL BIOLOGY (2004)
A proteomic analysis of arginine-methylated protein complexes
FM Boisvert et al.
MOLECULAR & CELLULAR PROTEOMICS (2003)
tr-kit promotes the formation of a multimolecular complex composed by Fyn, PLCγ1 and Sam68
MP Paronetto et al.
ONCOGENE (2003)
Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1
J Cote et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing
FM Boisvert et al.
JOURNAL OF CELL BIOLOGY (2002)
Signal-dependent regulation of splicing via phosphorylation of Sam68
N Matter et al.
NATURE (2002)
Large-scale proteomic analysis of the human splicesome
J Rappsilber et al.
GENOME RESEARCH (2002)
c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs
A Ostareck-Lederer et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Posttranslational mechanisms regulate the mammalian circadian clock
C Lee et al.
CELL (2001)
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln
G Meister et al.
CURRENT BIOLOGY (2001)
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo
E Martinez et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Transportin-SR2 mediates nuclear import of phosphorylated SR proteins
MC Lai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Insulin regulates alternative splicing of protein kinase C βII through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells
NA Patel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation
H Habelhah et al.
NATURE CELL BIOLOGY (2001)
Global histone acetylation and deacetylation in yeast
M Vogelauer et al.
NATURE (2000)
Htra2-β1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2)
Y Hofmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Dynamic changes in small nuclear ribonucleoproteins of heat-stressed and thermotolerant HeLa cells
U Bond et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2000)
Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains
MT Bedford et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The RGG domain in hnRNP A2 affects subcellular localization
RC Nichols et al.
EXPERIMENTAL CELL RESEARCH (2000)
A human importin-β family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins
MC Lai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)