4.7 Review

DNA Nanodevice-Based Drug Delivery Systems

期刊

BIOMOLECULES
卷 11, 期 12, 页码 -

出版社

MDPI
DOI: 10.3390/biom11121855

关键词

drug delivery; nanodevice; DNA framework; stimuli response; controllable release

资金

  1. National Natural Science Foundation of China [22074090]
  2. Natural Science Foundation of Shanghai [19ZR1474200]

向作者/读者索取更多资源

DNA, as a natural biological material, is increasingly being utilized for biomedical applications due to its biocompatibility, ease of synthesis, modifiability, and programmability. Advancements in DNA synthesis and modification technology have led to the development of smart-responsive DNA nanodevices that can intelligently respond to external stimuli, providing new solutions for targeted drug delivery and tumor treatment. Looking ahead, there are promising prospects for further advancements in this field.
DNA, a natural biological material, has become an ideal choice for biomedical applications, mainly owing to its good biocompatibility, ease of synthesis, modifiability, and especially programmability. In recent years, with the deepening of the understanding of the physical and chemical properties of DNA and the continuous advancement of DNA synthesis and modification technology, the biomedical applications based on DNA materials have been upgraded to version 2.0: through elaborate design and fabrication of smart-responsive DNA nanodevices, they can respond to external or internal physical or chemical stimuli so as to smartly perform certain specific functions. For tumor treatment, this advancement provides a new way to solve the problems of precise targeting, controllable release, and controllable elimination of drugs to a certain extent. Here, we review the progress of related fields over the past decade, and provide prospects for possible future development directions.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据