Course and Lethality of SARS-CoV-2 Epidemic in Nursing Homes after Vaccination in Florence, Italy

Article Medicine, General & Internal

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Merryn Voysey et al.

Summary: The ChAdOx1 nCoV-19 vaccine has been shown to have an acceptable safety profile and effectiveness against symptomatic COVID-19, with higher efficacy observed in the group that received a low dose followed by a standard dose.

LANCET (2021)

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Article Oncology

Cocooning Against COVID-19: The Argument for Vaccinating Caregivers of Patients With Cancer

Maresa C. Woodfield et al.

Summary: It is suggested that cocoon vaccination strategies should be used to protect cancer patients in the COVID-19 vaccination race. Medical systems specializing in cancer care should support education and vaccination campaigns targeting informal caregivers and household contacts, in addition to cancer patients.

CANCER (2021)

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Letter Immunology

Humoral and Cellular Immunogenicity of the BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccine in Nursing Home Residents

Jens T. Van Praet et al.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Immunology

Single Dose of an mRNA Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) Vaccine Is Associated With Lower Nasopharyngeal Viral Load Among Nursing Home Residents With Asymptomatic Coronavirus Disease 2019 (COVID-19)

M. Catherine McEllistrem et al.

Summary: A single dose of mRNA SARS-CoV-2 vaccine has been shown to lower the viral load in asymptomatic COVID-19 patients, potentially aiding in controlling outbreaks as viral load is linked to transmission.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Geriatrics & Gerontology

The BNT162b2 vaccine is associated with lower new COVID-19 cases in nursing home residents and staff

Marsida Domi et al.

Summary: After vaccination with the BNT162b2 vaccine, there was a decreasing trend observed in resident and staff cases and deaths in nursing homes. Time points 5 and 6 weeks post-vaccination consistently showed fewer resident cases, deaths, and staff cases. Other factors associated with reduced cases included smaller facilities and higher nurse staffing levels. Contrary to prior research, higher Hispanic non-white resident census was associated with fewer cases and deaths among residents.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2021)

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Article Geriatrics & Gerontology

Proportion of SARS-CoV-2 positive tests and vaccination in Veterans Affairs Community Living Centers

James L. Rudolph et al.

Summary: The proportion of SARS-CoV-2 positive tests significantly declined in VA Community Living Centers (CLCs) 4 weeks after vaccine delivery and continued to decline in vaccinated and unvaccinated residents. The results highlight the importance of surveillance and vaccination against SARS-CoV-2 in nursing home residents.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2021)

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Article Geriatrics & Gerontology

Short-term impact of nursing home SARS-CoV-2 vaccinations on new infections, hospitalizations, and deaths

Vincent Mor et al.

Summary: This study compared the impact of early and late administration of COVID-19 vaccines in nursing homes, finding that early vaccination can effectively reduce infection rates and hospitalization/death rates.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2021)

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Editorial Material Immunology

Are vaccines against COVID-19 tailored to the most vulnerable people?

Raffaele Antonelli Incalzi et al.

VACCINE (2021)

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Article Public, Environmental & Occupational Health

Postvaccination SARS-CoV-2 Infections Among Skilled Nursing Facility Residents and Staff Members - Chicago, Illinois, December 2020-March 2021

Richard A. Teran et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Article Geriatrics & Gerontology

Caring for nursing home residents with COVID-19: a hospital-at-nursing home intermediate care intervention

Enrico Benvenuti et al.

Summary: The study described an assistance model involving an intermediate care mobile medical specialist team (GIROT) aimed at delivering hospital-at-nursing home care to NH residents with COVID-19 in Florence, Italy. The intervention led to a significant decrease in hospitalization and lethality rates in NH residents with COVID-19 during the second wave of the pandemic.

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2021)

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Article Infectious Diseases