期刊
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
卷 9, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2021.662418
关键词
tissue engineering; scaffolds; growth factors; periodontal; dental implants; cleft palate; oral and maxillofacial skin or mucosa; oral and maxillofacial bone
资金
- Foundation of Science and Technology Department of Henan Province, China [212102310103]
- Natural Science Foundation of Education Department of Henan Province, China [21A320004]
- Foundation of National Health Commission of Henan Province, China [Wjlx2020017]
- Foundation of Science and Technology Department of Luoyang City, Henan Province, China [2101065A]
Tissue engineering is a new discipline that combines engineering and life sciences to construct functional biological structures for tissue and organ replacement. In dentistry research, tissue engineering has achieved impressive advancements in areas such as teeth, periodontal tissues, and dental implants.
Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures in vivo or in vitro to replace native tissues or organs and minimize serious shortages of donor organs during tissue and organ reconstruction or transplantation. Organ transplantation has achieved success by using the tissue-engineered heart, liver, kidney, and other artificial organs, and the emergence of tissue-engineered bone also provides a new approach for the healing of human bone defects. In recent years, tissue engineering technology has gradually become an important technical method for dentistry research, and its application in stomatology-related research has also obtained impressive achievements. The purpose of this review is to summarize the research advances of tissue engineering and its application in stomatology. These aspects include tooth, periodontal, dental implant, cleft palate, oral and maxillofacial skin or mucosa, and oral and maxillofacial bone tissue engineering. In addition, this article also summarizes the commonly used cells, scaffolds, and growth factors in stomatology and discusses the limitations of tissue engineering in stomatology from the perspective of cells, scaffolds, and clinical applications.
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