4.7 Article

Anatomical Transcriptome Atlas of the Male Mouse Reproductive System During Aging

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Andrology

Examination of testicular lumicrine regulation of activins and immunoregulatory genes in the epididymal caput

Rukmali Wijayarathna et al.

Summary: The study found that testicular lumicrine secretion can regulate several genes that are preferentially expressed in the initial segment of the epididymis, but has marginal effects on genes such as activin A and IDO1, which are expressed more widely in the caput.

ANDROLOGY (2022)

Article Multidisciplinary Sciences

Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis

Ming Wang et al.

Summary: Macrophages in the testis and epididymis originate from different stages of cell development and can self-maintain independently of bone marrow hematopoietic cells in a steady state. However, during radiation-induced macrophage ablation or infection, bone marrow-derived cells are recruited to the testis and epididymis, leading to an inflammatory response.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Article Genetics & Heredity

Outcome prediction of microdissection testicular sperm extraction based on extracellular vesicles piRNAs

Haicheng Chen et al.

Summary: This study identified 8 EV-piRNAs associated with spermatogenic ability, selected two EV-piRNAs (pir-60351 and pir-61927) using LASSO regression analysis, and developed a favorable model based on pir-61927 expression in seminal plasma EVs to predict the micro-TESE outcome in NOA patients with good discrimination and calibration.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2021)

Article Cell Biology

Spatio-temporal landscape of mouse epididymal cells and specific mitochondria-rich segments defined by large-scale single-cell RNA-seq

Jianwu Shi et al.

Summary: This study used single-cell RNA sequencing to reveal the cell composition, spatio-temporal differences in differentially expressed genes, and novel distribution pattern of mitochondria in the mouse epididymis. Key genes potentially linked to sperm functionality were identified, providing insights into sperm maturation regulation in the epididymis.

CELL DISCOVERY (2021)

Review Geriatrics & Gerontology

Collagens and elastin genetic variations and their potential role in aging-related diseases and longevity in humans

Roman Romero-Ortuno et al.

EXPERIMENTAL GERONTOLOGY (2020)

Article Geriatrics & Gerontology

Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration

Congcong Zhang et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2020)

Review Cell Biology

Molecular insights into the divergence and diversity of post-testicular maturation strategies

Brett Nixon et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)

Article Multidisciplinary Sciences

Ageing hallmarks exhibit organ-specific temporal signatures

Nicholas Schaum et al.

NATURE (2020)

Article Multidisciplinary Sciences

NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility

Daiji Kiyozumi et al.

SCIENCE (2020)

Article Neurosciences

A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks

Shradha Mukherjee et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Medicine, General & Internal

Paediatric and adult-onset male hypogonadism

Andrea Salonia et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Letter Cell Biology

Caput Epididymidal Mouse Sperm Support Full Development

Dongjie Zhou et al.

DEVELOPMENTAL CELL (2019)

Article Anatomy & Morphology

Three-dimensional structure of efferent and epididymal ducts in mice

Hiroki Nakata et al.

JOURNAL OF ANATOMY (2019)

Article Obstetrics & Gynecology

Cytological and molecular aspects of the ageing sperm

Donatella Paoli et al.

HUMAN REPRODUCTION (2019)

Article Cell Biology

Hormonal control of vas deferens fluid volume and aquaporin expression in rats

Nur Siti Khadijah Ramli et al.

JOURNAL OF MOLECULAR HISTOLOGY (2019)

Article Multidisciplinary Sciences

Motile cilia of the male reproductive system require miR-34/miR-449 for development and function to generate luminal turbulence

Shuiqiao Yuan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Andrology

Ageing and inflammation in the male reproductive tract

M. B. Frungieri et al.

ANDROLOGIA (2018)

Article Cell Biology

A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq

Christopher Daniel Green et al.

DEVELOPMENTAL CELL (2018)

Review Genetics & Heredity

Effects of aging on the male reproductive system

Sezgin Gunes et al.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2016)

Review Developmental Biology

Segment-specific regulation of epididymal gene expression

Petra Sipila et al.

REPRODUCTION (2016)

Article Biochemistry & Molecular Biology

The choroid plexus and the paradox of interferons in the aging brain

Suhayl Dhib-Jalbut

CYTOKINE (2015)

Review Endocrinology & Metabolism

Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring

Rakesh Sharma et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2015)

Article Geriatrics & Gerontology

Aging-related changes of optic nerve of Wistar albino rats

Hassan I. H. El-Sayyad et al.

Article Endocrinology & Metabolism

Androgenic regulation of beta-defensins in the mouse epididymis

Shuang-Gang Hu et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2014)

Article Obstetrics & Gynecology

Age thresholds for changes in semen parameters in men

Bronte A. Stone et al.

FERTILITY AND STERILITY (2013)

Article Medicine, Research & Experimental

Protamine and Fertilin mRNA: Potential Biomarkers of Assisted Reproductive Technology Outcomes

G. T. Sukhikh et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2012)

Review Andrology

Aging and Declining Testosterone: Past, Present, and Hopes for the Future

Barry R. Zirkin et al.

JOURNAL OF ANDROLOGY (2012)

Article Multidisciplinary Sciences

Rate of de novo mutations and the importance of father's age to disease risk

Augustine Kong et al.

NATURE (2012)

Review Endocrinology & Metabolism

Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy

Prasanth N. Surampudi et al.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2012)

Article Biochemical Research Methods

A simple protocol for assessing inter-trial and inter-examiner reliability for two noninvasive measures of limb muscle strength

C. George Carlson et al.

JOURNAL OF NEUROSCIENCE METHODS (2010)

Review Endocrinology & Metabolism

Ovarian Aging: Mechanisms and Clinical Consequences

F. J. Broekmans et al.

ENDOCRINE REVIEWS (2009)

Article Obstetrics & Gynecology

Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia

Takahiro Haraguchi et al.

FERTILITY AND STERILITY (2009)

Review Cell Biology

Leydig cell aging and the mechanisms of reduced testosterone synthesis

Andrew S. Midzak et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)

Article Reproductive Biology

The rat epididymal transcriptome: Comparison of segmental gene expression in the rat and mouse epididymides

Scott A. Jelinsky et al.

BIOLOGY OF REPRODUCTION (2007)

Review Endocrinology & Metabolism

The road to maleness: from testis to Wolffian duct

Ivraym Barsoum et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2006)

Article Geriatrics & Gerontology

Effects of methyl-ß-cyclodextrin on T lymphocytes lipid rafts with aging

A Larbi et al.

EXPERIMENTAL GERONTOLOGY (2004)

Article Biochemistry & Molecular Biology

Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense systems in testicular rat Leydig cells

LC Cao et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2004)

Article Geriatrics & Gerontology

The expression of the RLF/INSL3 gene is reduced in Leydig cells of the aging rat testis

HJ Paust et al.

EXPERIMENTAL GERONTOLOGY (2002)