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Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses
Yang Ou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
Wan Seok Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Ferrootosis: Death by Lipid Peroxidation
Wan Seok Yang et al.
TRENDS IN CELL BIOLOGY (2016)
Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression
Shang-Jui Wang et al.
CELL REPORTS (2016)
An essential cell-autonomous role for hepcidin in cardiac iron homeostasis
Samira Lakhal-Littleton et al.
ELIFE (2016)
Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer
Wei-Ching Chen et al.
PLOS ONE (2016)
Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity
Kenichi Shimada et al.
CELL CHEMICAL BIOLOGY (2016)
The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis
Yang Liu et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2015)
Effects of deferasirox-deferoxamine on myocardial and liver iron in patients with severe transfusional iron overload
Yesim Aydinok et al.
BLOOD (2015)
Ceruloplasmin activity and iron chelation treatment of patients with Parkinson's disease
Guillaume Grolez et al.
BMC NEUROLOGY (2015)
Elucidating Compound Mechanism of Action by Network Perturbation Analysis
Jung Hoon Woo et al.
CELL (2015)
T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
Mai Matsushita et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Glutaminolysis and Transferrin Regulate Ferroptosis
Minghui Gao et al.
MOLECULAR CELL (2015)
High nigral iron deposition in LRRK2 and Parkin mutation carriers using R2*relaxometry
Nadya Pyatigorskaya et al.
MOVEMENT DISORDERS (2015)
Ferroptosis as a p53-mediated activity during tumour suppression
Le Jiang et al.
NATURE (2015)
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function
Liangyu Chen et al.
ONCOLOGY REPORTS (2015)
Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function
Samira Lakhal-Littleton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE
Scott Ayton et al.
NATURE COMMUNICATIONS (2015)
Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism
Qing Lu et al.
REDOX BIOLOGY (2015)
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L. Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2015)
Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease
David Devos et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Role of duodenal iron transporters and hepcidin in patients with alcoholic liver disease
Marketa Dostalikova-Cimburova et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2014)
Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
Rachid Skouta et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Joseph D. Mancias et al.
NATURE (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
The role of iron and reactive oxygen species in cell death
Scott J. Dixon et al.
NATURE CHEMICAL BIOLOGY (2014)
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Scott J. Dixon et al.
ELIFE (2014)
Cystine/glutamic acid transporter is a novel marker for predicting poor survival in patients with hepatocellular carcinoma
Hiroki Kinoshita et al.
ONCOLOGY REPORTS (2013)
Iron Accumulates in Huntington's Disease Neurons: Protection by Deferoxamine
Jianfang Chen et al.
PLOS ONE (2013)
Cancer drug resistance: an evolving paradigm
Caitriona Holohan et al.
NATURE REVIEWS CANCER (2013)
Iron and cancer: more ore to be mined
Suzy V. Torti et al.
NATURE REVIEWS CANCER (2013)
The transsulfuration pathway: a source of cysteine for glutathione in astrocytes
Gethin J. McBean
AMINO ACIDS (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Ironing Out Cell Death Mechanisms
John C. Reed et al.
CELL (2012)
Systematic review of β-Elemene injection as adjunctive treatment for lung cancer
Wang Bin et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2012)
Trigonelline: A Plant Alkaloid with Therapeutic Potential for Diabetes and Central Nervous System Disease
J. Zhou et al.
CURRENT MEDICINAL CHEMISTRY (2012)
Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice
Junghee Lee et al.
ACTA NEUROPATHOLOGICA (2011)
Blood-derived iron mediates free radical production and neuronal death in the hippocampal CA1 area following transient forebrain ischemia in rat
Ui Jin Park et al.
ACTA NEUROPATHOLOGICA (2011)
Long-term safety and efficacy of deferasirox (Exjade®) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease
Elliott Vichinsky et al.
BRITISH JOURNAL OF HAEMATOLOGY (2011)
Programmed Cell Death in Animal Development and Disease
Yaron Fuchs et al.
CELL (2011)
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
Alice T. Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen
Hany Onsy Habashy et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Iron-binding and anti-Fenton properties of baicalein and baicalin
Carlos A. Perez et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2009)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
Wan Seok Yang et al.
CHEMISTRY & BIOLOGY (2008)
Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice
ZhongMao Guo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects
Natasa Klepac et al.
JOURNAL OF NEUROLOGY (2007)
Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis
Qitao Ran et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2007)
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
Nicholas Yagoda et al.
NATURE (2007)
Divorcing ARF and p53: an unsettled case
Charles J. Sherr
NATURE REVIEWS CANCER (2006)
Pharmacokinetics of dietary phenethyl isothiocyanate in rats
Y Ji et al.
PHARMACEUTICAL RESEARCH (2005)
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