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Recombinant Thrombomodulin Exerts Anti-autophagic Action in Endothelial Cells and Provides Anti-atherosclerosis Effect in Apolipoprotein E Deficient Mice
Po-Sheng Chen et al.
SCIENTIFIC REPORTS (2017)
Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness
Emma P. K. Yu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)
Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure
Tammo Mueller et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis
Mireille Ouimet et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)
HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
Shan Zhu et al.
CANCER RESEARCH (2017)
Intact endothelial autophagy is required to maintain vascular lipid homeostasis
Kumiko Torisu et al.
AGING CELL (2016)
Serum Ferritin Relates to Carotid Intima-Media Thickness in Offspring of Fathers With Higher Serum Ferritin Levels
Anna Prats-Puig et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Loss of cysteinyl-tRNA synthetase ( CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
M. Hayano et al.
CELL DEATH AND DIFFERENTIATION (2016)
Correlation of NLRP3 with severity and prognosis of coronary atherosclerosis in acute coronary syndrome patients
Altaf Afrasyab et al.
HEART AND VESSELS (2016)
Pseudomonas aeruginosa Triggers Macrophage Autophagy To Escape Intracellular Killing by Activation of the NLRP3 Inflammasome
Qiuchan Deng et al.
INFECTION AND IMMUNITY (2016)
The roles of macrophage autophagy in atherosclerosis
Bo-zong Shao et al.
ACTA PHARMACOLOGICA SINICA (2016)
NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx
Michael A. Katsnelson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)
Spermidine reduces lipid accumulation and necrotic core formation in atherosclerotic plaques via induction of autophagy
Cederic F. Michiels et al.
ATHEROSCLEROSIS (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2016)
Autophagy promotes ferroptosis by degradation of ferritin
Wen Hou et al.
AUTOPHAGY (2016)
An essential role for functional lysosomes in ferroptosis of cancer cells
Seiji Torii et al.
BIOCHEMICAL JOURNAL (2016)
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
Zhenyu Zhong et al.
CELL (2016)
Ferroptosis is an autophagic cell death process
Minghui Gao et al.
CELL RESEARCH (2016)
Pyroptosis as a Regulated Form of Necrosis PI+/Annexin V-/High Caspase 1/Low Caspase 9 Activity in Cells = Pyroptosis?
Jun-ichi Abe et al.
CIRCULATION RESEARCH (2016)
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
Michael A. Gimbrone et al.
CIRCULATION RESEARCH (2016)
Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial Cells
Hang Xi et al.
CIRCULATION RESEARCH (2016)
The roles of autophagy in vascular smooth muscle cells
Shi Tai et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)
Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis
Wei Li et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties
Sam Hofmans et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement
Tingting Wang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Porphyromonas gingivalis Lipopolysaccharide Stimulation of Vascular Smooth Muscle Cells Activates Proliferation and Calcification
Guirong Liu et al.
JOURNAL OF PERIODONTOLOGY (2016)
Addition of Cleaved Tail Fragments during Lipid Oxidation Stabilizes Membrane Permeability Behavior
Kristina A. Runas et al.
LANGMUIR (2016)
Pore-forming activity and structural autoinhibition of the gasdermin family
Jingjin Ding et al.
NATURE (2016)
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Xing Liu et al.
NATURE (2016)
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
Kenichi Shimada et al.
NATURE CHEMICAL BIOLOGY (2016)
Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth
Sung Eun Kim et al.
NATURE NANOTECHNOLOGY (2016)
The Loss of Myocardial Benefit following Ischemic Preconditioning Is Associated with Dysregulation of Iron Homeostasis in Diet-Induced Diabetes
Vladimir Vinokur et al.
PLOS ONE (2016)
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
Robin A. Aglietti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
Wan Seok Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Cadmium induces NLRP3 inflammasome-dependent pyroptosis in vascular endothelial cells
Haiyan Chen et al.
TOXICOLOGY LETTERS (2016)
Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids
Audrey Swiader et al.
ONCOTARGET (2016)
Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
Scott J. Dixon et al.
ACS CHEMICAL BIOLOGY (2015)
Early Hyperlipidemia Promotes Endothelial Activation via a Caspase-1-Sirtuin 1 Pathway
Ying Yin et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)
Hepcidin-ferroportin axis controls toll-like receptor 4 dependent macrophage inflammatory responses in human atherosclerotic plaques
Anwer Habib et al.
ATHEROSCLEROSIS (2015)
Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis
Mandy O. J. Grootaert et al.
AUTOPHAGY (2015)
ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms
Lulu Li et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2015)
Lower AMP-activated protein kinase level is associated with the vulnerability of coronary atherosclerotic plaques by attenuating the expression of monocyte autophagy
Jing Cheng et al.
CORONARY ARTERY DISEASE (2015)
Recent insights into cell death and autophagy
Brent E. Fitzwalter et al.
FEBS JOURNAL (2015)
The small GTPase Rab7 as a central regulator of hepatocellular lipophagy
Barbara Schroeder et al.
HEPATOLOGY (2015)
Oxidized LDL attenuates protective autophagy and induces apoptotic cell death of endothelial cells: Role of oxidative stress and LOX-1 receptor expression
Vincenzo Mollace et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)
Inhibition of Caspase-1 Activation in Endothelial Cells Improves Angiogenesis A NOVEL THERAPEUTIC POTENTIAL FOR ISCHEMIA
Jahaira Lopez-Pastrana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
TPD52 expression increases neutral lipid storage within cultured cells
Alvin Kamili et al.
JOURNAL OF CELL SCIENCE (2015)
Caspase-1 Activity Is Required for UVB-Induced Apoptosis of Human Keratinocytes
Gabriel Sollberger et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
Expression of the NLRP3 Inflammasome in Carotid Atherosclerosis
Xin Shi et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2015)
Glutaminolysis and Transferrin Regulate Ferroptosis
Minghui Gao et al.
MOLECULAR CELL (2015)
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki et al.
NATURE (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
Ferroptosis as a p53-mediated activity during tumour suppression
Le Jiang et al.
NATURE (2015)
Expression of the NLRP3 Inflammasome in Carotid Atherosclerosis
Xin Shi et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2015)
Posttranslational modification of autophagy-related proteins in macroautophagy
Yangchun Xie et al.
AUTOPHAGY (2015)
Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives
Ema Ozaki et al.
JOURNAL OF INFLAMMATION RESEARCH (2015)
An Overview of Autophagy: Morphology, Mechanism, and Regulation
Katherine R. Parzych et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Defining the membrane precursor supporting the nucleation of the phagophore
Amelie Bernard et al.
AUTOPHAGY (2014)
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
Sayak K. Mitter et al.
AUTOPHAGY (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis
Sima Allahverdian et al.
CIRCULATION (2014)
Effects of vitamin E on peroxisome proliferator-activated receptor γ and nuclear factor-erythroid 2-related factor 2 in hypercholesterolemia-induced atherosclerosis
Perinur Bozaykut et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Joseph D. Mancias et al.
NATURE (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
The role of iron and reactive oxygen species in cell death
Scott J. Dixon et al.
NATURE CHEMICAL BIOLOGY (2014)
Silence of NLRP3 Suppresses Atherosclerosis and Stabilizes Plaques in Apolipoprotein E-Deficient Mice
Fei Zheng et al.
MEDIATORS OF INFLAMMATION (2014)
Autophagic Marker MAP1LC3B Expression Levels Are Associated with Carotid Atherosclerosis Symptomatology
Bhairavi Swaminathan et al.
PLOS ONE (2014)
MiR-216a: a link between endothelial dysfunction and autophagy
R. Menghini et al.
CELL DEATH & DISEASE (2014)
Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection
Christopher R. Lupfer et al.
PLOS PATHOGENS (2014)
PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress
Joshua K. Salabei et al.
BIOCHEMICAL JOURNAL (2013)
Triglyceride-Induced Macrophage Cell Death Is Triggered by Caspase-1
Sin Jee Son et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2013)
Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection
Youssef Aachoui et al.
CURRENT OPINION IN MICROBIOLOGY (2013)
Implications of autophagy for vascular smooth muscle cell function and plasticity
Joshua K. Salabei et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Association of genetic polymorphisms in ADH and ALDH2 with risk of coronary artery disease and myocardial infarction: A meta-analysis
Hongguang Han et al.
GENE (2013)
Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7g
Zufeng Ding et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: Potential role in atherosclerosis
Dang-Heng Wei et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)
Pyroptosis: An inflammatory cell death implicates in atherosclerosis
Wei Chang et al.
MEDICAL HYPOTHESES (2013)
Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?
Jing Lin et al.
PLOS ONE (2013)
Targeting annexin A7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase C in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein E-/- mice
H. Li et al.
CELL DEATH & DISEASE (2013)
Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis
Zufeng Ding et al.
SCIENTIFIC REPORTS (2013)
Macrophages in atherosclerosis: a dynamic balance
Kathryn J. Moore et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Sonic hedgehog promotes autophagy of vascular smooth muscle cells
Haijie Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Ferritin Is Independently Associated With the Presence of Coronary Artery Calcium in 12033 Men
Ki-Chul Sung et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells
Enrico Desideri et al.
AUTOPHAGY (2012)
Development of small-molecule probes that selectively kill cells induced to express mutant RAS
Michel Weiwer et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Caspase-1 Deficiency Decreases Atherosclerosis in Apolipoprotein E-Null Mice
Jessica Gage et al.
CANADIAN JOURNAL OF CARDIOLOGY (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Kenichi Shimada et al.
IMMUNITY (2012)
Phosphatidylinositol 3-kinases and their roles in phagosome maturation
Emily P. Thi et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
Translational evidence that impaired autophagy contributes to arterial ageing
Thomas J. LaRocca et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
The Beclin 1 network regulates autophagy and apoptosis
R. Kang et al.
CELL DEATH AND DIFFERENTIATION (2011)
A clinical perspective of IL-1β as the gatekeeper of inflammation
Charles A. Dinarello
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Autophagy, reactive oxygen species and the fate of mammalian cells
Irena Szumiel
FREE RADICAL RESEARCH (2011)
Caspase-1-induced pyroptotic cell death
Edward A. Miao et al.
IMMUNOLOGICAL REVIEWS (2011)
Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression
Stephane Potteaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
Franz Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2011)
A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou et al.
NATURE (2011)
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki et al.
NATURE (2011)
Progress and challenges in translating the biology of atherosclerosis
Peter Libby et al.
NATURE (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira et al.
NATURE IMMUNOLOGY (2011)
Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging
Douglas R. Green et al.
SCIENCE (2011)
Vascular Smooth Muscle Cell Apoptosis Induces Interleukin-1-Directed Inflammation Effects of Hyperlipidemia-Mediated Inhibition of Phagocytosis
Murray C. H. Clarke et al.
CIRCULATION RESEARCH (2010)
Autophagy and the Integrated Stress Response
Guido Kroemer et al.
MOLECULAR CELL (2010)
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Peter Duewell et al.
NATURE (2010)
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Rongbin Zhou et al.
NATURE IMMUNOLOGY (2010)
Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
Kristiina Rajamaki et al.
PLOS ONE (2010)
Autophagy of HSP70 and chelation of lysosomal iron in a non-redox-active form
Tino Kurz et al.
AUTOPHAGY (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
Pyroptosis: host cell death and inflammation
Tessa Bergsbaken et al.
NATURE REVIEWS MICROBIOLOGY (2009)
Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells
W. Martinet et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-Mediated cell death
Alexander Seiler et al.
CELL METABOLISM (2008)
Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
Wan Seok Yang et al.
CHEMISTRY & BIOLOGY (2008)
Overexpression of transferrin receptor and ferritin related to clinical symptoms and destabilization of human carotid plaques
Wei Li et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2008)
Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice
ZhongMao Guo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
Tatsuya Saitoh et al.
NATURE (2008)
Subendothelial lipoprotein retention as the initiating process in atherosclerosis -: Update and therapeutic implications
Ira Tabas et al.
CIRCULATION (2007)
Innate immunity, macrophage activation, and atherosclerosis
Zhong-qun Yan et al.
IMMUNOLOGICAL REVIEWS (2007)
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
Susan L. Fink et al.
CELLULAR MICROBIOLOGY (2006)
Insulin-like growth factor-1 and TNF-α regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells
Guanghong Jia et al.
IMMUNOLOGY AND CELL BIOLOGY (2006)
Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
SL Fink et al.
INFECTION AND IMMUNITY (2005)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
LC3 conjugation system in mammalian autophagy
I Tanida et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Apoptosis, autophagy, and more
RA Lockshin et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading
JX Rong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
From vulnerable plaque to vulnerable patient - A call for new definitions and risk assessment strategies: Part II
M Naghavi et al.
CIRCULATION (2003)
Macrophage-specific p53 expression plays a crucial role in atherosclerosis development and plaque remodeling
AJ Merched et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)
Depletion of phospholipid hydroperoxide glutathione peroxidase up-regulates arachidonate metabolism by 12(S)-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells
CJ Chen et al.
FASEB JOURNAL (2003)
Extracellular nucleotides induce arterial smooth muscle cell migration via osteopontin
H Chaulet et al.
CIRCULATION RESEARCH (2001)
Molecular dissection of autophagy: Two ubiquitin-like systems
Y Ohsumi
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Cell biology - Autophagy as a regulated pathway of cellular degradation
DJ Klionsky et al.
SCIENCE (2000)
Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death
FD Kolodgie et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)