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Recent Progress in Surface Modification of Mg Alloys for Biodegradable Orthopedic Applications

FRONTIERS IN MATERIALS (2022)

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Article Materials Science, Multidisciplinary

Intermetallic-Rich Layer Formation for Improving Corrosion Resistance of Magnesium Alloys

D. Calderon et al.

Summary: This study investigates the formation of a corrosion protective coating containing intermetallic phases on magnesium alloy substrates. The coating, formed by vacuum thermal evaporation of commercially pure aluminum and subsequent heat treatment, was continuous and homogenous with a microstructure composed of a eutectic phase. This eutectic-type coating provided significant protection for both commercially pure magnesium and AZ31 alloy samples inside a salt spray chamber.

METALS AND MATERIALS INTERNATIONAL (2022)

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Article Engineering, Biomedical

On the corrosion, stress corrosion and cytocompatibility performances of ALD TiO2 and ZrO2 coated magnesium alloys

M. Peron et al.

Summary: Magnesium alloys are being studied as materials for temporary implants, but their high corrosion rate and susceptibility to corrosion-assisted cracking phenomena continue to prevent mainstream use. Coatings, particularly those deposited using Atomic Layer Deposition (ALD), have shown promise in reducing corrosion rate and stress corrosion cracking susceptibility. Consideration of coatings' properties such as wettability, electrochemical stability, and surface integrity is crucial in understanding and improving the performance of coated magnesium alloys.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2022)

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Article Materials Science, Characterization & Testing

Effect of Grain Refinement by Laser Surface Treatment on Cell Adhesion Behavior of AZ91D Magnesium Alloy

Changgang Guo et al.

Summary: Laser surface melting (LSM) has been widely used for corrosion protection of magnesium alloys, but in this study, the cell adhesion behavior of AZ91D magnesium alloy by LSM treatment was investigated. The results showed that LSM-treated magnesium alloys had lower biodegradation rate, higher surface energy, and increased surface roughness, leading to improved cytocompatibility and cell adhesion.

JOURNAL OF TESTING AND EVALUATION (2021)

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Article Emergency Medicine

Healthcare utilization and related cost of midshaft clavicle fracture treatment in Belgium

Michiel Herteleer et al.

Summary: The study found that the initial healthcare utilization cost of operatively treated midshaft clavicle fractures is higher than that of non-operatively treated fractures. Length-of-stay is the most important parameter that drives the cost, influenced primarily by patients' age, fracture complexity, and complications requiring surgical re-intervention.

EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY (2021)

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Article Materials Science, Multidisciplinary

In vitrodegradation and mechanical behaviour of calcium phosphate coated Mg-Ca alloy

Shebeer A. Rahim et al.

Summary: The study investigated the use of calcium phosphate (CaP) coating on magnesium-calcium alloys in physiological environments to improve biomineralization and reduce degradation rates. The CaP coating was found to help control the reduction in mechanical properties of the alloys in physiological environments.

MATERIALS TECHNOLOGY (2021)

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Article Chemistry, Physical

Electrochemical characterization of electrophoretically deposited hydroxyapatite/chitosan/graphene oxide composite coating on Mg substrate

Ahmad Saadati et al.

Summary: In this study, magnesium alloys were coated with hydroxyapatite/chitosan using electrophoretic deposition method with different graphene oxide content. It was found that adding 1% graphene oxide and applying 150V potential significantly improved the corrosion resistance of the magnesium alloys. The microstructure of the coatings showed a significant relationship with their corrosion resistance, potentially due to the formation of well dispersed, low porosity, and relatively dense composite coatings.

SURFACES AND INTERFACES (2021)

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Article Materials Science, Coatings & Films

Magnesium alloys for biomedical application: Advanced corrosion control through surface coating

Robert B. Heimann

Summary: The development of magnesium alloys for biomedical applications requires the use of protective coatings and the development of advanced alloy formulations with enhanced corrosion resistance. Research focuses on improving the biostability of magnesium alloys in simulated body fluid and in vivo environments, mainly through surface coatings and osseoconductive coatings.

SURFACE & COATINGS TECHNOLOGY (2021)

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Article Metallurgy & Metallurgical Engineering

Investigating TiO2-HA-PCL hybrid coating as an efficient corrosion resistant barrier of ZM21 Mg alloy

Navdeep Singh et al.

Summary: The research focuses on the design and development of TiO2-HA-PCL hybrid coating for improving the corrosion resistance of Mg alloys. The hybrid coating introduces strong hydrogen bonding and Vander wall electrostatic interaction, enhancing adhesion strength and corrosion potentials. Through immersion testing and weight loss measurements, the TiO2-HA-PCL coating demonstrates superior corrosion resistance compared to TiO2-HA coating.

JOURNAL OF MAGNESIUM AND ALLOYS (2021)

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Article Metallurgy & Metallurgical Engineering

Poly caprolactone/titanium dioxide nanofiber coating on AM50 alloy for biomedical application

Mani Karthega et al.

Summary: The study involved the preparation of PCL/TiO2 composite nanofiber on AM50 alloy surface using electrospinning technique. The results showed that the AM50 alloy coated with PCL/6 wt% TiO2 exhibited excellent cellular proliferation support and corrosion resistance in SBF solution.

JOURNAL OF MAGNESIUM AND ALLOYS (2021)

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Article Materials Science, Ceramics

Ternary hydroxyapatite/chitosan/graphene oxide composite coating on AZ91D magnesium alloy by electrophoretic deposition

R. Askarnia et al.

Summary: Ternary HA/chitosan/graphene oxide (GO) coating was successfully deposited on AZ91D magnesium alloy as bone implants. The addition of GO resulted in increased hardness, improved HA growth, decreased corrosion rate, and enhanced antibacterial properties of the composite coatings.

CERAMICS INTERNATIONAL (2021)

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Article Materials Science, Multidisciplinary

Fabrication of superhydrophobic composite coating of hydroxyapatite/stearic acid on magnesium alloy and its corrosion resistance, antibacterial adhesion

Qianqian Li et al.

Summary: The study prepared a superhydrophobic composite coating of hydroxyapatite/stearic acid on magnesium alloy, demonstrating excellent superhydrophobicity and long-term corrosion resistance, as well as good antibacterial adhesion properties in simulated body fluid. This provides a surface modification strategy for magnesium alloy implants in orthopedics and dentistry.

JOURNAL OF MATERIALS SCIENCE (2021)

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Article Chemistry, Physical

Evolution of gradient structured layer on AZ91D magnesium alloy and its corrosion behaviour

Digvijay Singh et al.

Summary: This study investigates the effects of SMAT treatment on the microstructure evolution and corrosion response of AZ91D magnesium alloy. TEM analysis reveals the introduction of compressive residual stress, nanoscale grains, and various twinning modes in the SMATed layer. Corrosion testing shows that the corrosion rate of SMATed specimens is significantly higher compared to non-SMATed specimens.

JOURNAL OF ALLOYS AND COMPOUNDS (2021)

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Review Biotechnology & Applied Microbiology

Functional Gradient Metallic Biomaterials: Techniques, Current Scenery, and Future Prospects in the Biomedical Field

Hongyuan Shi et al.

Summary: Functional gradient materials (FGMs) can provide multiple functions and mimic natural systems' structure, showing great potential in biomedical applications. Despite various advantages, a notable lack of comprehensive guidelines and standards indicates the need for further research in the field.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

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Article Metallurgy & Metallurgical Engineering

Microstructure and surface texture driven improvement in in-vitro response of laser surface processed AZ31B magnesium alloy

Tso-Chang Wu et al.

Summary: The study investigated the effects of laser surface melting on microstructure and surface topography evolution in AZ31B magnesium alloy, revealing that laser surface melting led to the formation of a refined microstructure and a progressively rougher surface. This resulted in improved wettability, corrosion resistance, and precipitation of mineral closer to hydroxyapatite in simulated body fluid for the samples treated with laser surface melting compared to untreated samples.

JOURNAL OF MAGNESIUM AND ALLOYS (2021)

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Article Nanoscience & Nanotechnology

Tuning of the Mg Alloy AZ31 Anodizing Process for Biodegradable Implants

Andrea Zaffora et al.

Summary: Coatings were grown on the AZ31 Mg alloy via a hard anodizing process in the hot glycerol phosphate-containing electrolyte. The optimized anodizing conditions and post-anodizing annealing treatment further enhanced the corrosion resistance of the coatings, mainly composed of magnesium phosphate. The coatings exhibited good biocompatibility and are suitable for biomedical devices.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Materials Science, Biomaterials

Micro-arc oxidation-assisted sol-gel preparation of calcium metaphosphate coatings on magnesium alloys for bone repair

Yanping Liu et al.

Summary: The calcium metaphosphate (CMP) coating fabricated on magnesium alloy using sol-gel approach assisted with microarc oxidation pre-treatment significantly improves the corrosion resistance and promotes the adhesion and osteogenic cell activity of bone marrow stem cells.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Article Biochemistry & Molecular Biology

Role of Surface Preparation in Corrosion Resistance Due to Silane Coatings on a Magnesium Alloy

Abhishek Saxena et al.

Summary: Coating with organo-silane has been found to enhance the corrosion resistance of magnesium alloy AZ91D, with a specific alkali treatment improving the corrosion resistance of the coated alloy by facilitating the condensation of a relatively compact siloxane film.

MOLECULES (2021)

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Article Materials Science, Multidisciplinary

Plasma-Sprayed Hydroxyapatite-Strontium Coating for Improved Corrosion Resistance and Surface Properties of Biodegradable AZ31 Mg Alloy for Biomedical Applications

Puneet Bansal et al.

Summary: Plasma-sprayed pure HA and HA/Sr reinforced coatings significantly improved the surface properties and corrosion resistance of Mg alloys, showing promise for future bone implant applications.

JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE (2021)

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Article Chemistry, Applied

Bilayer micro-arc oxidation-poly (glycerol sebacate) coating on AZ91 for improved corrosion resistance and biological activity

Mohsen Ghafarzadeh et al.

Summary: The study found that the bilayer MAO-PGS coatings significantly improved the corrosion resistance and biocompatibility of the AZ91 alloy. Different electrospraying times had a significant impact on the coating properties, with the 3-hour coating showing the best performance. Noticeably, the adhesion strength of the MAO-PGS coating was directly modulated by the PGS coating time.

PROGRESS IN ORGANIC COATINGS (2021)

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Article Orthopedics

被撤回的出版物: An experimental study on stress-shielding effects of locked compression plates in fixing intact dog femur (Retracted article. See vol. 17, 2022)

Xinwen Zhao et al.

Summary: Comparison of stress-shielding effects between locked compression plate (LCP) and limited-contact dynamic compression plate (LC-DCP) in dog femurs revealed that LCP group demonstrated better bone cell morphology, bone mineral density, and reduced degree of cortical bone osteoporosis compared to the LC-DCP group. Biomechanical analyses also showed that bones fixed with LCP had superior compressive and flexural strength. These findings suggest that LCP is more beneficial for new bone formation and fracture healing compared to LC-DCP.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2021)

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Article Metallurgy & Metallurgical Engineering

Does acid pickling of Mg-Ca alloy enhance biomineralization?

Shebeer A. Rahim et al.

Summary: The surface modification of Mg-Ca alloy by acid pickling significantly improved biomineralization and developed in situ calcium phosphate coating. Treated samples showed reduced degradation rate in simulated body fluid (SBF) compared to untreated samples, suggesting acid pickling as an effective method to tailor the performance of Mg-Ca alloy in physiological environment.

JOURNAL OF MAGNESIUM AND ALLOYS (2021)

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Review Materials Science, Multidisciplinary

Recent Developments and Novel Applications of Laser Shock Peening: A Review

Chaoyi Zhang et al.

Summary: Laser shock peening (LSP) enhances fatigue performance of metallic components by inducing work hardening and beneficial compressive residual stresses, with applications in emerging fields and innovative process development. This comprehensive review covers the history, mechanisms, effects, and recent developments in LSP.

ADVANCED ENGINEERING MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Biomimicking Bone-Implant Interface Facilitates the Bioadaption of a New Degradable Magnesium Alloy to the Bone Tissue Microenvironment

Wenting Li et al.

Summary: A new magnesium-based implant alloy has been designed to coordinate its biodegradation with the bone regenerative process through a self-assembled, multilayered bone-implant interface. This biomimicking interface proves to be adaptable in vivo, regulating degradation and accelerating bone mineralization.

ADVANCED SCIENCE (2021)

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Article Chemistry, Applied

Polycaprolactone tridentate ligand corrosion inhibitors coated on biodegradable Mg implant

Hamouda M. Mousa et al.

Summary: AZ31 magnesium alloy coated with a blend of polycaprolactone and amino acid Schiff base showed high corrosion inhibition efficiency, making it a promising material for bone tissue engineering applications. The sample was characterized and evaluated for corrosion behavior using various techniques, and in vitro bioactivity was confirmed through osteoblast cell experiments.

JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH (2021)

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Article Materials Science, Multidisciplinary

Improving the in vitro Degradation, Mechanical and Biological Properties of AZ91-3Ca Mg Alloy via Hydrothermal Calcium Phosphate Coatings

Asif Ali et al.

Summary: This study investigated the biological response of single-step hydrothermally deposited calcium phosphate coatings using Alamar blue assay, cell attachment, live/dead assay, and qRT-PCR. Immersion testing in SBF and compression testing were carried out to examine the degradation behavior and mechanical properties. Results indicated that the coatings significantly influenced the substrate performance and structural integrity of coated AZ91-3Ca alloy. The coatings enhanced the mRNA levels for RUNX2, Col1A, and ALP, leading towards faster bone regeneration.

FRONTIERS IN MATERIALS (2021)

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Article Materials Science, Multidisciplinary

Preliminary Studies for One-Step Fabrication of Metallic Iron-Based Coatings on Magnesium as Temporary Protection in Biodegradable Medical Application

Yuyun Yang et al.

Summary: Iron and magnesium are considered promising candidates for biodegradable materials in medical applications, with a study showing a layered composite of metallic iron and magnesium combining the merits of both metals. Assessment using various methods revealed that the Mg/Fe layered composite sheet exhibited a self-healing effect in the culture medium.

FRONTIERS IN MATERIALS (2021)

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Review Biotechnology & Applied Microbiology

The Role of Biodegradable Magnesium and Its Alloys in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis Based on Animal Studies

Zhizhong Shang et al.

Summary: The study found that magnesium and its alloys have great potential in anterior cruciate ligament reconstruction, with better mechanical properties and ability to promote new bone formation compared to titanium and its alloys. However, further research is needed to investigate the degradation rate of magnesium and its alloy and its matching with bone-tendon integration rate.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

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Review Engineering, Biomedical

Clinical translation and challenges of biodegradable magnesium-based interference screws in ACL reconstruction

Ying Luo et al.

Summary: This paper discusses the advantages, mechanisms, technical challenges, and improvement methods of biodegradable magnesium-based interference screws in anterior cruciate ligament reconstruction, and proposes suggestions for developing new strategies.

BIOACTIVE MATERIALS (2021)

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Article Materials Science, Multidisciplinary

Bed of nails: bioinspired nano-texturing towards antibacterial and bioactivity functions

D. Chopra et al.

Summary: Nanostructured implants inspired by nature show potential in preventing bacterial infection but require careful consideration of biocompatibility and bioactivity. Further research is needed for the development of advanced biomimetic nano-engineered implants.

MATERIALS TODAY ADVANCES (2021)

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Article Materials Science, Coatings & Films

A composite coating with physical interlocking and chemical bonding on WE43 magnesium alloy for corrosion protection and cytocompatibility enhancement

Haili Zhou et al.

Summary: A composite coating composed of PLLA/APTES/hydroxide nanosheets was successfully prepared on magnesium alloy surface to enhance corrosion resistance and cytocompatibility. The coating structure design effectively retards the corrosion rate by increasing chemical bonding active sites and physical interlocking properties, demonstrating improved protection against corrosion of magnesium alloy.

SURFACE & COATINGS TECHNOLOGY (2021)

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Review Materials Science, Multidisciplinary

Additively Manufactured Absorbable Porous Metal Implants - Processing, Alloying and Corrosion Behavior

Holger Jahr et al.

Summary: Absorbable porous metals manufactured by additive manufacturing offer customizable multi-scale geometries, interconnected porous structure, and tunable absorption properties for bone regeneration and remodeling. Thorough characterization of their biodegradation behavior, mechanical properties, and bone regeneration ability is essential for developing ideal implants. In comparison to solid inert counterparts, AM absorbable porous metals possess unique properties and potential, but face challenges in future Orthopedic solutions.

FRONTIERS IN MATERIALS (2021)

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Article Engineering, Biomedical

Preparation and characterization of chitosan/graphene oxide nanocomposite coatings on Mg-2 wt% Zn scaffold by pulse electrodeposition process

Mohammad Ranjbar Hamghavandi et al.

Summary: In this study, chitosan/graphene oxide nanocomposite coatings were fabricated to improve the corrosion resistance of Mg-2 wt% Zn scaffold, with the optimal fabrication conditions identified through investigating the coating microstructures and reaction parameters; The potentiodynamic polarization measurement in simulated body fluid showed that the CS/GO coatings effectively protected the scaffolds against corrosion, and the optimal sample demonstrated adequate biocompatibility with proper adhesion of mouse fibroblast cells on the CS-2 wt% GO coating.

BIOMEDICAL MATERIALS (2021)

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Article Engineering, Biomedical

Copper coating formed by micro-arc oxidation on pure Mg improved antibacterial activity, osteogenesis, and angiogenesis in vivo and in vitro

Dong-yu Liang et al.

Summary: By using micro-arc oxidation (MAO) and adding copper to pure magnesium, the resulting coating showed enhanced antibacterial, angiogenic, and osteogenic activities, making it a promising material for biomedical applications.

BIOMEDICAL MICRODEVICES (2021)

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Article Materials Science, Multidisciplinary

Sacrificial protection of Mg-based resorbable implant alloy by magnetron sputtered Mg5Gd alloy coating: A short-term study

K. A. Yasakau et al.

Summary: The study found that the coating of Mg5Gd alloy pins effectively reduced the corrosion rate, and revealed the corrosion mechanism of the coating through various electrochemical measurements.

CORROSION SCIENCE (2021)

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Review Engineering, Biomedical

Design approaches and challenges for biodegradable bone implants: a review

Girish Chandra et al.

Summary: This review delves into the parametrically conceptualized design of biodegradable bone implants, considering the characteristics of bone-biodegradable implant interface, design techniques, traditional design, finite element analysis approaches, manufacturing techniques, and real-time surgical simulations. It emphasizes the need to reconceptualize and design conventional nonbiodegradable bone implants with appropriate biodegradable materials to balance all factors and fulfill desired orthopedic requirements.

EXPERT REVIEW OF MEDICAL DEVICES (2021)

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Article Biochemistry & Molecular Biology

Corrosion Resistance of MgZn Alloy Covered by Chitosan-Based Coatings

Iryna Kozina et al.

Summary: Spin coating technique was used to deposit chitosan coatings on the surface of Mg20Zn magnesium alloy, resulting in increased corrosion resistance by forming CaSiO3 and Ca-3(PO4)(2) compounds on its surface. Corrosion rate was reduced from 3.2 mm/year to 1.2 mm/year for uncoated and coated substrates, respectively.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Materials Science, Coatings & Films

Sol-gel coatings doped with graphene nanoplatelets for improving the degradation rate and the cytocompatibility of AZ31 alloy for biomedical applications

J. P. Fernandez-Hernan et al.

Summary: This study investigated the effect of SiO2 coatings doped with different functionalized graphene nanoplatelets on the corrosion rate and cytocompatibility of magnesium alloy. The results showed that varying nanoplatelets concentrations affected the protective behavior of the coatings and cellular responses in culture.

SURFACE & COATINGS TECHNOLOGY (2021)

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Article Materials Science, Coatings & Films

Microstructure and improved anti-corrosion properties of cold-sprayed Zn coatings fabricated by post shot-peening process

Hai-Long Yao et al.

Summary: In this study, a Zn coating was formed on Mg alloy through cold spraying technology and then subjected to post shot-peening processing to improve corrosion resistance. The shot-peened Zn coatings showed densification, increased hardness, and significantly enhanced anti-corrosion properties compared to cold-sprayed Zn coatings.

SURFACE & COATINGS TECHNOLOGY (2021)

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Article Materials Science, Coatings & Films

Electrophoretically deposited high molecular weight chitosan/bioactive glass composite coatings on WE43 magnesium alloy

Agnieszka Witecka et al.

Summary: Composite coatings based on chitosan and bioactive glass particles fabricated by electrophoretic deposition on pre-treated magnesium alloys show promising potential in bone regeneration applications by suppressing substrate corrosion and promoting cell response.

SURFACE & COATINGS TECHNOLOGY (2021)

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Article Materials Science, Coatings & Films

Surface properties modification of magnesium alloys by low energy high current pulsed electron beam

Federico Morini et al.

Summary: The effects of LEHCEB treatment on the surface properties of AZ91D and AM60B magnesium alloys were investigated by controlling beam energy and number of pulses. Characterization of surface layers was done using XRD, EDS, and GDOES. The results showed that surface modification had a significant impact on the mechanical properties and corrosion resistance of the alloys.

SURFACE & COATINGS TECHNOLOGY (2021)

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Article Materials Science, Coatings & Films

Effects of strontium-substitution in sputter deposited calcium phosphate coatings on the rate of corrosion of magnesium alloys

Jonathan G. Acheson et al.

Summary: Magnesium alloys have potential for use in bioresorbable orthopaedic implant devices, but controlling corrosion rate is a challenge. RF magnetron sputtering has been used to create coatings on magnesium alloys which significantly decrease corrosion rate.

SURFACE & COATINGS TECHNOLOGY (2021)

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Article Multidisciplinary Sciences

Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge

Weixian Xi et al.

Summary: The authors present a prophylactic coating technology that can incorporate various antibiotics and be applied in vivo prior to implantation, effectively preventing joint implant infections.

NATURE COMMUNICATIONS (2021)

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Review Engineering, Biomedical

Diamond in the Rough: Toward Improved Materials for the Bone-Implant Interface

Jessica S. L. Fong et al.

Summary: This article explores the recent advances and future prospects for diamond-based coatings of conventional osteo-implant materials, emphasizing the ability of these coatings to improve integration with existing bone, enhance implant mechanical properties, facilitate surface chemical functionalization, and provide anti-microbial properties. In addition, diamond coatings may have an osteo-inductive effect, improving implant integration through stem cell recruitment and bone regeneration. Current research is highlighted to support further improvement in implant integration through an osseoinductive effect from diamond composite materials.

ADVANCED HEALTHCARE MATERIALS (2021)

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Review Immunology

Recent Advances in Research on Antibacterial Metals and Alloys as Implant Materials

Juyang Jiao et al.

Summary: Implants are widely used in orthopedic surgery, but their use is limited by implant-associated infections (IAI). One promising strategy to prevent and treat IAI is designing metal materials with antibacterial functions by alloying methods. Understanding the complex interaction between bacteria, host cells, and materials is crucial for the development and clinical translation of antibacterial metals and alloys.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

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Review Materials Science, Multidisciplinary

A Comprehensive Review on Surface Modifications of Biodegradable Magnesium-Based Implant Alloy: Polymer Coatings Opportunities and Challenges

Abbas Saberi et al.

Summary: The development of biodegradable implants using magnesium alloys faces challenges such as fast degradation, hydrogen gas generation, and pH value elevation in body solution. Surface modification is a practical approach to improve corrosion resistance and enhance bone regeneration and cell attachment. Metal coatings, ceramic coatings, and permanent polymers have been shown to minimize degradation rates, but bioabsorbable polymers are generally preferred for their desired biocompatibility.

COATINGS (2021)

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Review Cell Biology

Magnesium Promotes the Regeneration of the Peripheral Nerve

Jingxin Zhang et al.

Summary: Magnesium as a suitable material for promoting peripheral nerve regeneration has both challenges and potentials, but there is currently limited research on this topic, requiring further exploration to address the shortcomings and challenges identified.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

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Article Chemistry, Multidisciplinary

Pure Mg-Al Layered Double Hydroxide Film on Magnesium Alloys for Orthopedic Applications

Shi Cheng et al.

Summary: The study successfully prepared a pure Mg-Al LDH film and demonstrated its potential in enhancing the corrosion resistance and biocompatibility of AZ31 materials. The LDH-coated sample not only promotes bone cell activity and bone regeneration, but also facilitates the functionality of vascular endothelial cells and angiogenesis.

ACS OMEGA (2021)

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Article Materials Science, Ceramics

Effect of ZnO nanoparticles addition to PEO coatings on AZ31B Mg alloy: antibacterial effect and corrosion behavior of coatings in Ringer's physiological solution

Mahya Seyfi et al.

Summary: In this study, the PEO technique was utilized to modify the surface of AZ31B Mg alloy, investigating the effects of adding ZnO and HAp nanoparticles on the antibacterial and corrosion behavior of coatings. Results showed that increasing the concentration of ZnO nanoparticles enhanced the antibacterial activity of coatings, reduced corrosion current density, and improved corrosion resistance.

JOURNAL OF ASIAN CERAMIC SOCIETIES (2021)

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Article Materials Science, Ceramics

Nano-hydroxyapatite/ZnO coating prepared on a biodegradable Mg-Zn-Ca bulk metallic glass by one-step hydrothermal method in acid situation

Jie Zhou et al.

CERAMICS INTERNATIONAL (2020)

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Article Materials Science, Multidisciplinary

Formation of a protective layer against corrosion on Mg alloy via alkali pretreatment followed by vanillic acid treatment

Sheng Li et al.

MATERIALS AND CORROSION-WERKSTOFFE UND KORROSION (2020)

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Article Materials Science, Biomaterials

Co-incorporation of graphene oxide/silver nanoparticle into poly-L-lactic acid fibrous: A route toward the development of cytocompatible and antibacterial coating layer on magnesium implants

Hamid Reza Bakhsheshi-Rad et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

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Fabrication, characterisation and corrosion of HA coated AZ31B Mg implant material: Effect of electrodeposition current density

Mohammad Uddin et al.

SURFACE & COATINGS TECHNOLOGY (2020)

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Article Materials Science, Coatings & Films

Surface modification of biodegradable AZ91 magnesium alloy by electrospun polymer nanocomposite: Evaluation of in vitro degradation and cytocompatibility

Z. Panahi et al.

SURFACE & COATINGS TECHNOLOGY (2020)

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Design of biodegradable, implantable devices towards clinical translation

Chunmei Li et al.

NATURE REVIEWS MATERIALS (2020)

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Corrosion Resistance and Biocompatibility Assessment of a Biodegradable Hydrothermal-Coated Mg-Zn-Ca Alloy: An in Vitro and in Vivo Study

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Failure after proximal humeral fracture osteosynthesis: a one year analysis of hospital-related healthcare cost

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PLA deposition on surface treated magnesium alloy: Adhesion, toughness and corrosion behaviour

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Structure and corrosion behavior of TiO2 thin films deposited onto Mg-based alloy using magnetron sputtering and sol-gel

Aneta Kania et al.

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POLYMERS (2020)

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Krzysztof Bryla et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

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Fabrication and characterization of silk fibroin coating on APTES pretreated Mg-Zn-Ca alloy

Chenxi Wang et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

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Tailoring biomineralization and biodegradation of Mg-Ca alloy by acetic acid pickling

Shebeer A. Rahim et al.

MATERIALS RESEARCH EXPRESS (2020)

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Article Metallurgy & Metallurgical Engineering

Microstructure and corrosion resistance of a Mg2Sn-dispersed Mg alloy subjected to pulsed electron beam treatment

Daseul Lee et al.

JOURNAL OF MAGNESIUM AND ALLOYS (2020)

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Article Materials Science, Multidisciplinary

Preparation and Degradation Behavior of Composite Bio-Coating on ZK60 Magnesium Alloy Using Combined Micro-Arc Oxidation and Electrophoresis Deposition

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Surface modification of magnesium alloys developed for bioabsorbable orthopedic implants: A general review

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Effect of laser surface melting on corrosion behaviour of AZ91D Mg alloy in simulated-modified body fluid

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Effect of high current pulsed electron beam treatment on surface microstructure and wear and corrosion resistance of an AZ91HP magnesium alloy

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