期刊
WORLD JOURNAL OF CLINICAL CASES
卷 10, 期 3, 页码 1122-1130出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.12998/wjcc.v10.i3.1122
关键词
Sigmoid colon cancer; Colorectal cancer; Anal metastasis; Recurrence; Case report
Colorectal cancer metastasis to the anus is rare, with low recurrence rates. This case reports a recurrence after 10 years, highlighting the risk. Literature review and discussion of potential mechanisms provide treatment suggestions.
BACKGROUND Distant metastasis of colorectal cancer to the anus is very rare, with only 30 related cases published in PubMed thus far. Therefore, recurrence of colorectal cancer derived anus metastases is rarely seen and less presented. CASE SUMMARY Here we report an 80-year-old male patient who underwent radical resection for sigmoid colon cancer in January 2010 and another surgery for anal fistula resection in December 2010. Postoperative pathology of the anal fistula revealed a metastatic moderately differentiated adenocarcinoma. The patient subsequently received chemotherapy and radiotherapy. In May 2020, after the patient reported symptoms of anal swelling and pain, computed tomography and magnetic resonance imaging revealed a perianal abscess. Perianal mass biopsy was performed, and the postoperative pathological diagnosis was metastatic moderately differentiated adenocarcinoma. CONCLUSION This case highlights that there is a risk of recurrence of anal metastasis of colorectal cancer even after 10 years of follow-up. We also reviewed the literature and discuss potential mechanisms for anal metastasis of colorectal cancer, thus providing some suggestions for treatment of these cases.
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