Towards a Digital Twin of Coronary Stenting: A Suitable and Validated Image-Based Approach for Mimicking Patient-Specific Coronary Arteries

Article Engineering, Biomedical

Validation of the computational model of a coronary stent: a fundamental step towards in silico trials

Luca Antonini et al.

Summary: The study suggests considering possible sources of variability in numerical model results and conducting experimental validation to prove its efficacy.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2021)

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Article Engineering, Biomedical

Comprehensive computational analysis of the crimping procedure of PLLA BVS: effects of material viscous-plastic and temperature dependent behavior

Luca Antonini et al.

Summary: The focus of the study was on the use of polymeric bioresorbable vascular scaffolds as an alternative to permanent metallic drug-eluting stents for the treatment of atherosclerotic coronary arteries. Computational simulations were conducted to evaluate how different strategies can influence the risk of damage and final crimped diameter, showing significant differences when neglecting strain rate and temperature dependence in the material model.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2021)

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Article Multidisciplinary Sciences

Computational and experimental mechanical performance of a new everolimus-eluting stent purpose-built for left main interventions

Saurabhi Samant et al.

Summary: The study investigated the mechanical performance of a novel everolimus-eluting stent designed for left main coronary artery interventions, demonstrating that the 12-peak MEGATRON had superior expansion, scaffolding, vessel prolapse, and radial strength compared to other stent designs. Computational simulations accurately reproduced experimental stent testing, providing a cost-effective framework for stent research and development.

SCIENTIFIC REPORTS (2021)

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Article Multidisciplinary Sciences

From the real device to the digital twin: A coupled experimental-numerical strategy to investigate a novel bioresorbable vascular scaffold

Luca Antonini et al.

Summary: This study proposes a workflow that combines experimental and computational activities to develop a credible digital twin of a commercial coronary bioresorbable vascular scaffold. By purchasing and conducting mechanical tests, the material model was calibrated to successfully develop a digital twin that replicates the mechanical behavior of the device.

PLOS ONE (2021)

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Article Engineering, Biomedical

How to Validate in silico Deployment of Coronary Stents: Strategies and Limitations in the Choice of Comparator

Francesca Berti et al.

Summary: This study proposes useful indications for validating a numerical model of coronary stent deployment, focusing on the use of 3D-printed mock vessels for experimental activities. The aim is to provide data for the validation of computational models and predict stent deployment.

FRONTIERS IN MEDICAL TECHNOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

European Society of Cardiology: Cardiovascular Disease Statistics 2019

Adam Timmis et al.

EUROPEAN HEART JOURNAL (2020)

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Review Cardiac & Cardiovascular Systems

The 'Digital Twin' to enable the vision of precision cardiology

Jorge Corral-Acero et al.

EUROPEAN HEART JOURNAL (2020)

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Review Cardiac & Cardiovascular Systems

The 'Digital Twin' to enable the vision of precision cardiology

Jorge Corral-Acero et al.

EUROPEAN HEART JOURNAL (2020)

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Proceedings Paper Engineering, Biomedical

Is modeling stents still an important issue?

Francesco Migliavacca

INTERNATIONAL CONFERENCE ON STENTS: MATERIALS, MECHANICS AND MANUFACTURING (ICS3M 2019) (2019)

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Article Automation & Control Systems

Digital twin-driven product design, manufacturing and service with big data

Fei Tao et al.

INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY (2018)

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Article Cardiac & Cardiovascular Systems

Biomechanical Impact of Wrong Positioning of a Dedicated Stent for Coronary Bifurcations: A Virtual Bench Testing Study

Claudio Chiastra et al.

CARDIOVASCULAR ENGINEERING AND TECHNOLOGY (2018)

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Proceedings Paper Engineering, Mechanical

Computational Evaluation of Artery Damage in Stent Deployment

Ran He et al.

ECF22 - LOADING AND ENVIRONMENTAL EFFECTS ON STRUCTURAL INTEGRITY (2018)

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Article Engineering, Biomedical

Numerical Simulation of Stent Angioplasty with Predilation: An Investigation into Lesion Constitutive Representation and Calcification Influence

C. Conway et al.

ANNALS OF BIOMEDICAL ENGINEERING (2017)

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Article Engineering, Biomedical

Numerical analysis of stent expansion process in coronary artery stenosis with the use of non-compliant balloon

Jakub Bukala et al.

BIOCYBERNETICS AND BIOMEDICAL ENGINEERING (2016)

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Article Biophysics

A Methodology for the Derivation of Unloaded Abdominal Aortic Aneurysm Geometry With Experimental Validation

Santanu Chandra et al.

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME (2016)

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Article Biophysics

Computational replication of the patient-specific stenting procedure for coronary artery bifurcations: From OCT and CT imaging to structural and hemodynamics analyses

Claudio Chiastra et al.

JOURNAL OF BIOMECHANICS (2016)

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Article Physics, Multidisciplinary

Nonparametric Denoising Methods Based on Contour let Transform with Sharp Frequency Localization: Application to Low Exposure Time Electron Microscopy Images

Soumia Sid Ahmed et al.

ENTROPY (2015)

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Review Cardiac & Cardiovascular Systems

Stent thrombosis and restenosis: what have we learned and where are we going? The Andreas Gruntzig Lecture ESC 2014

Robert A. Byrne et al.

EUROPEAN HEART JOURNAL (2015)

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Article Cardiac & Cardiovascular Systems

Noninvasive Fractional Flow Reserve Derived From Coronary CT Angiography Clinical Data and Scientific Principles

James K. Min et al.

JACC-CARDIOVASCULAR IMAGING (2015)

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Article Engineering, Biomedical

Computational Modelling of Multi-folded Balloon Delivery Systems for Coronary Artery Stenting: Insights into Patient-Specific Stent Malapposition

Georgios E. Ragkousis et al.

ANNALS OF BIOMEDICAL ENGINEERING (2015)

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Article Biophysics

Mechanical properties of human atherosclerotic intima tissue

Ali C. Akyildiz et al.

JOURNAL OF BIOMECHANICS (2014)

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Review Biotechnology & Applied Microbiology

Endothelium and Its Alterations in Cardiovascular Diseases: Life Style Intervention

Gaia Favero et al.

BIOMED RESEARCH INTERNATIONAL (2014)

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Article Biophysics

Local axial compressive mechanical properties of human carotid atherosclerotic plaques-characterisation by indentation test and inverse finite element analysis

Chen-Ket Chai et al.

JOURNAL OF BIOMECHANICS (2013)

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Article Engineering, Biomedical

Patient-specific simulations of stenting procedures in coronary bifurcations: Two clinical cases

Stefano Morlacchi et al.

MEDICAL ENGINEERING & PHYSICS (2013)

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Article Biophysics

Geometry parameterization and multidisciplinary constrained optimization of coronary stents

Sanjay Pant et al.

BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2012)

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Article Biophysics

3D computational parametric analysis of eccentric atheroma plaque: influence of axial and circumferential residual stresses

M. Cilla et al.

BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2012)

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Article Biophysics

Experimental determination of circumferential properties of fresh carotid artery plaques

Michael G. Lawlor et al.

JOURNAL OF BIOMECHANICS (2011)

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Article Biophysics

Modelling of the provisional side-branch stenting approach for the treatment of atherosclerotic coronary bifurcations: effects of stent positioning

Dario Gastaldi et al.

BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2010)

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Article Biophysics

Tensile and compressive properties of fresh human carotid atherosclerotic plaques

Eoghan Maher et al.

JOURNAL OF BIOMECHANICS (2009)

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Review Multidisciplinary Sciences

Hyperelastic modelling of arterial layers with distributed collagen fibre orientations

TC Gasser et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2006)

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Article Cardiac & Cardiovascular Systems

Determination of layer-specific mechanical properties of human coronary arteries with nonatherosclerotic intimal thickening and related constitutive modeling

GA Holzapfel et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)

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Towards a Digital Twin of Coronary Stenting: A Suitable and Validated Image-Based Approach for Mimicking Patient-Specific Coronary Arteries

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