期刊
GASTROENTEROLOGY REPORT
卷 9, 期 6, 页码 505-520出版社
OXFORD UNIV PRESS
DOI: 10.1093/gastro/goab040
关键词
hepatorenal syndrome; acute-on-chronic liver failure; acute kidney injury; review
资金
- Scientific Research Project of Beijing You'an Hospital [CCMU 2019]
- China Primary Health Care Foundation-Youan Foundation of Liver Disease and AIDS [BJYAYY-GG2019-01]
This review discusses the association between hepatorenal syndrome and acute-on-chronic liver failure in cirrhotic patients, highlighting the progress and controversies in diagnosis and treatment. The need for more active research on treating difficult diseases is emphasized to improve prognosis.
In cirrhosis with ascites, hepatorenal syndrome (HRS) is a specific prerenal dysfunction unresponsive to fluid volume expansion. Acute-on-chronic liver failure (ACLF) comprises a group of clinical syndromes with multiple organ failure and early high mortality. There are differences in the characterization of ACLF between the Eastern and Western medical communities. Patients with ACLF and acute kidney injury (AKI) have more structural injuries, contributing to confusion in diagnosing HRS-AKI. In this review, we discuss progress in the pathogenesis, diagnosis, and management of HRS-AKI, especially in patients with ACLF. Controversy regarding HRS-AKI in ACLF and acute liver failure, hepatic carcinoma, shock, sepsis, and chronic kidney disease is also discussed. Research on the treatment of HRS-AKI with ACLF needs to be more actively pursued to improve disease prognosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据