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Seng Chuan Tang et al.
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Evita van de Steeg et al.
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G Szakács et al.
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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
AH Schinkel et al.
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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
JW Jonker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)