4.7 Review

Cell-Penetrating Peptides: Emerging Tools for mRNA Delivery

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

Delivery of synthetic mRNAs for tissue regeneration

Heidrun Steinle et al.

Summary: Nucleic acid-based therapeutics, particularly synthetic mRNA, have emerged as promising drugs for disease prevention and treatment. Recent advances in using synthetic mRNA-based vaccines against COVID-19 have shown significant potential. The introduction of novel chemical modifications and different delivery vehicles have enhanced the efficiency and uptake of mRNA molecules for therapeutic applications.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Review Pharmacology & Pharmacy

Advances in mRNA non-viral delivery approaches

Maria L. Ibba et al.

Summary: Messenger RNA (mRNA) holds great potential as therapeutics for various human pathologies, but the key to its clinical translation lies in the development of safe and effective delivery strategies. Non-viral delivery systems, although slightly less efficacious compared to viral systems, offer important advantages in terms of biosafety and versatility. Challenges and future applications of mRNA therapeutics are also discussed in this review.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Review Immunology

mRNA-Based Cancer Vaccines: A Therapeutic Strategy for the Treatment of Melanoma Patients

Maryam Bidram et al.

Summary: mRNA vaccines are considered a modern option for cancer treatment, with advantages such as rapid production, low manufacturing costs, and the ability to induce both cellular and humoral immune responses. However, their use is also associated with challenges that require extensive trials to validate their efficacy.

VACCINES (2021)

Review Biotechnology & Applied Microbiology

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

Namit Chaudhary et al.

Summary: mRNA vaccines have been established as a rapid, effective, and safe approach for protecting individuals from infectious diseases, especially during the COVID-19 pandemic. Further research is needed to optimize mRNA vaccine design, delivery, and applications for a range of infectious diseases.

NATURE REVIEWS DRUG DISCOVERY (2021)

Article Medicine, Research & Experimental

Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders

Androulla N. Miliotou et al.

Summary: The study developed an innovative method combining IVT-mRNAs with protein transduction domain (PTD) technology as an efficient delivery platform, which was successfully applied and evaluated in two protein-disease models. The novel delivery platform could potentially be clinically applicable as a protein therapy for metabolic/genetic disorders.

MOLECULAR THERAPY-NUCLEIC ACIDS (2021)

Review Nanoscience & Nanotechnology

Lipid nanoparticles for mRNA delivery

Xucheng Hou et al.

Summary: Lipid nanoparticle-mRNA formulations have successfully entered clinical use as COVID-19 vaccines, representing a major milestone in mRNA therapeutics. This review discusses the design of lipid nanoparticles for mRNA delivery, emphasizing key points for clinical translation and preclinical studies of lipid nanoparticle-mRNA therapeutics for various diseases.

NATURE REVIEWS MATERIALS (2021)

Article Chemistry, Multidisciplinary

A helix foldamer oligopeptide improves intracellular stability and prolongs protein expression of the delivered mRNA

Satoshi Uchida et al.

Summary: Prolonging protein expression from mRNA is a challenge in mRNA nanomedicine development. mRNA complexed with helix foldamer oligopeptides containing arginine and alpha-aminoisobutyric acids showed higher intracellular stability and maintained efficient protein translation for three days.

NANOSCALE (2021)

Article Chemistry, Multidisciplinary

De Novo Design of Cell-penetrating Foldamers

Hidetomo Yokoo et al.

CHEMICAL RECORD (2020)

Review Biotechnology & Applied Microbiology

Advances in oligonucleotide drug delivery

Thomas C. Roberts et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Review Medicine, Research & Experimental

Nanomedicine-Based Approaches for mRNA Delivery

Satoshi Uchida et al.

MOLECULAR PHARMACEUTICS (2020)

Review Biotechnology & Applied Microbiology

Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases

Itishri Sahu et al.

MOLECULAR THERAPY (2019)

Article Multidisciplinary Sciences

Secondary structures and cell-penetrating abilities of arginine-rich peptide foldamers

Makoto Oba et al.

SCIENTIFIC REPORTS (2019)

Article Pharmacology & Pharmacy

Peptide-mediated delivery of therapeutic mRNA in ovarian cancer

Dirk van den Brand et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

Article Materials Science, Biomaterials

Plasmid DNA Delivery Using Cell-Penetrating Peptide Foldamers Composed of Arg-Arg-Aib Repeating Sequences

Makoto Oba et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2019)

Review Pharmacology & Pharmacy

Recent CPP-based applications in medicine

Kaido Kurrikoff et al.

EXPERT OPINION ON DRUG DELIVERY (2019)

Article Chemistry, Multidisciplinary

Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide

Yingshan Qiu et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Article Chemistry, Multidisciplinary

Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium

Asha Kumari Patel et al.

ADVANCED MATERIALS (2019)

Review Engineering, Biomedical

Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA

Satoshi Uchida et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2019)

Article Biochemistry & Molecular Biology

Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway

Takuto Nogimori et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Chemistry, Organic

Kinetic Resolution of Ansa Cyclophanes by Peptide-Catalyzed Aldol/Retro-Aldol Reactions

Kengo Akagawa et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)

Article Biotechnology & Applied Microbiology

Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis

Ema Robinson et al.

MOLECULAR THERAPY (2018)

Review Biochemistry & Molecular Biology

Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics

Graham McClorey et al.

BIOMEDICINES (2018)

Article Biotechnology & Applied Microbiology

Lipid Nanoparticle Systems for Enabling Gene Therapies

Pieter R. Cullis et al.

MOLECULAR THERAPY (2017)

Review Pharmacology & Pharmacy

Cell-Penetrating Peptides: From Basic Research to Clinics

Giulia Guidotti et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2017)

Review Nanoscience & Nanotechnology

Tools for translation: non-viral materials for therapeutic mRNA delivery

Khalid A. Hajj et al.

NATURE REVIEWS MATERIALS (2017)

Article Chemistry, Multidisciplinary

Cell-Surface Interactions on Arginine-Rich Cell-Penetrating Peptides Allow for Multiplex Modes of Internalization

Shiroh Futaki et al.

ACCOUNTS OF CHEMICAL RESEARCH (2017)

Article Engineering, Biomedical

Lipopolyplex potentiates anti-tumor immunity of mRNA-based vaccination

Stefano Persano et al.

BIOMATERIALS (2017)

Review Pharmacology & Pharmacy

Peptides for nucleic acid delivery

Taavi Lehto et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Article Biochemistry & Molecular Biology

Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids

Takuma Kato et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2016)

Article Chemistry, Multidisciplinary

Dynamic foldamer chemistry

Bryden A. F. Le Bailly et al.

CHEMICAL COMMUNICATIONS (2016)

Review Pharmacology & Pharmacy

Delivery of therapeutic oligonucleotides with cell penetrating peptides

Prisca Boisguerin et al.

ADVANCED DRUG DELIVERY REVIEWS (2015)

Review Biochemistry & Molecular Biology

Helical Screw-Sense Preferences of Peptides Based on Chiral, Cα-Tetrasubstituted α-Amino Acids

Marco Crisma et al.

BIOPOLYMERS (2015)

Article Pharmacology & Pharmacy

Dry Powder Formulation of Plasmid DNA and siRNA for Inhalation

Michael Y. T. Chow et al.

CURRENT PHARMACEUTICAL DESIGN (2015)

Article Chemistry, Organic

A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides

Yosuke Demizu et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2015)

Editorial Material Pharmacology & Pharmacy

Cell-penetrating peptides transport therapeutics into cells

Joshua D. Ramsey et al.

PHARMACOLOGY & THERAPEUTICS (2015)

Article Multidisciplinary Sciences

Nebulisation of IVT mRNA Complexes for Intrapulmonary Administration

Sarah M. Johler et al.

PLOS ONE (2015)

Review Biochemistry & Molecular Biology

Mechanism Maters: A Taxonomy of Cell Penetrating Peptices

W. Berkeley Kauffman et al.

TRENDS IN BIOCHEMICAL SCIENCES (2015)

Review Chemistry, Multidisciplinary

Cell-Penetrating Peptides: Design, Synthesis, and Applications

Dana Maria Copolovici et al.

ACS NANO (2014)

Article Respiratory System

Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma

Yukari Asai-Tajiri et al.

RESPIRATORY RESEARCH (2014)

Article Biochemistry & Molecular Biology

Bioinspired Self-Assembled Peptide Nanofibers with Thermostable Multivalent α-Helices

So-hee Han et al.

BIOMACROMOLECULES (2013)

Review Biochemistry & Molecular Biology

Cell-penetrating peptides: 20 years later, where do we stand?

Cherine Bechara et al.

FEBS LETTERS (2013)

Article Medicine, Research & Experimental

Modified Foxp3 mRNA protects against asthma through an IL-10 dependent mechanism

Lauren E. Mays et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Chemistry, Multidisciplinary

Encapsulation of Nod1 and Nod2 receptor ligands into poly(lactic acid) nanoparticles potentiates their immune properties

Vincent Pavot et al.

JOURNAL OF CONTROLLED RELEASE (2013)

Review Chemistry, Multidisciplinary

Peptide Vectors for the Nonviral Delivery of Nucleic Acids

Jan Hoyer et al.

ACCOUNTS OF CHEMICAL RESEARCH (2012)

Review Chemistry, Multidisciplinary

mRNA as gene therapeutic: How to control protein expression

Geertrui Tavernier et al.

JOURNAL OF CONTROLLED RELEASE (2011)

Article Multidisciplinary Sciences

Global quantification of mammalian gene expression control

Bjoern Schwanhaeusser et al.

NATURE (2011)

Article Biotechnology & Applied Microbiology

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

Michael S. D. Kormann et al.

NATURE BIOTECHNOLOGY (2011)

Review Biotechnology & Applied Microbiology

Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines

Anil Mahapatro et al.

JOURNAL OF NANOBIOTECHNOLOGY (2011)

Review Pharmacology & Pharmacy

Synthetic therapeutic peptides: science and market

Patrick Vlieghe et al.

DRUG DISCOVERY TODAY (2010)

Article Chemistry, Multidisciplinary

Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation

Hidetaka Akita et al.

JOURNAL OF CONTROLLED RELEASE (2010)

Article Chemistry, Multidisciplinary

Design and Evaluation of Histidine-Rich Amphipathic Peptides for siRNA Delivery

Berangere Langlet-Bertin et al.

PHARMACEUTICAL RESEARCH (2010)

Article Oncology

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

Kazuki N. Sugahara et al.

CANCER CELL (2009)

Article Public, Environmental & Occupational Health

Dry powder aerosol delivery systems: Current and future research directions

HK Chan

JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG (2006)

Review Pharmacology & Pharmacy

GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery

WJ Li et al.

ADVANCED DRUG DELIVERY REVIEWS (2004)

Review Pharmacology & Pharmacy

Arginine containing peptides as delivery vectors

CH Tung et al.

ADVANCED DRUG DELIVERY REVIEWS (2003)

Article Biochemistry & Molecular Biology

Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells

T Bettinger et al.

NUCLEIC ACIDS RESEARCH (2001)

Article Chemistry, Multidisciplinary

An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides

CE Schafmeister et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)