相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria
Ilyas Alav et al.
CHEMICAL REVIEWS (2021)
Bacterial efflux transporters' polyspecificity-a gift and a curse?
Helen Zgurskaya et al.
CURRENT OPINION IN MICROBIOLOGY (2021)
RND efflux pumps in Gram-negative bacteria; regulation, structure and role in antibiotic resistance
Abigail L. Colclough et al.
FUTURE MICROBIOLOGY (2020)
Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex
Marie Glavier et al.
NATURE COMMUNICATIONS (2020)
Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains
Olivier Cunrath et al.
EBIOMEDICINE (2019)
Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism
Kenta Tsutsumi et al.
NATURE COMMUNICATIONS (2019)
Conformational Dynamics of AcrA Govern Multidrug Efflux Pump Assembly
Anthony J. Hazel et al.
ACS INFECTIOUS DISEASES (2019)
Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-ToIC Multidrug Efflux Pump
Narges Abdali et al.
ACS INFECTIOUS DISEASES (2017)
To the G20: incentivising antibacterial research and development
Christine Ardal et al.
LANCET INFECTIOUS DISEASES (2017)
Dynamics of Intact MexAB-OprM Efflux Pump: Focusing on the MexA-OprM Interface
Cesar A. Lopez et al.
SCIENTIFIC REPORTS (2017)
An overview of bacterial efflux pumps and computational approaches to study efflux pump inhibitors
Shirin Jamshidi et al.
FUTURE MEDICINAL CHEMISTRY (2016)
The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
Xian-Zhi Li et al.
CLINICAL MICROBIOLOGY REVIEWS (2015)
Structure, mechanism and cooperation of bacterial multidrug transporters
Dijun Du et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2015)
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
Samuel Genheden et al.
EXPERT OPINION ON DRUG DISCOVERY (2015)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Structure of the Tripartite Multidrug Efflux Pump AcrAB-TolC Suggests an Alternative Assembly Mode
Jin-Sik Kim et al.
MOLECULES AND CELLS (2015)
Assembly and operation of bacterial tripartite multidrug efflux pumps
Dijun Du et al.
TRENDS IN MICROBIOLOGY (2015)
Molecular mechanisms of antibiotic resistance
Jessica M. A. Blair et al.
NATURE REVIEWS MICROBIOLOGY (2015)
Structure-function analysis of the ATP-driven glycolipid efflux pump DevBCA reveals complex organization with TolC/HgdD
Peter Staron et al.
FEBS LETTERS (2014)
β-Lactam Selectivity of Multidrug Transporters AcrB and AcrD Resides in the Proximal Binding Pocket
Naoki Kobayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Structure of the AcrAB-TolC multidrug efflux pump
Dijun Du et al.
NATURE (2014)
Structure and Operation of Bacterial Tripartite Pumps
Philip Hinchliffe et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 67 (2013)
RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms
Paolo Ruggerone et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Clinical relevance of the ESKAPE pathogens
Jack N. Pendleton et al.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2013)
Improved Generalized Born Solvent Model Parameters for Protein Simulations
Hai Nguyen et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
Flexible docking and refinement with a coarse-grained protein model using ATTRACT
Sjoerd de Vries et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2013)
New antibiotics for bad bugs: where are we?
Matteo Bassetti et al.
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS (2013)
Stoichiometry of the MexA-OprM binding, as investigated by blue native gel electrophoresis
Yann Ferrandez et al.
ELECTROPHORESIS (2012)
Interdomain Flexibility and pH-Induced Conformational Changes of AcrA Revealed by Molecular Dynamics Simulations
Beibei Wang et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
Sequential Mechanism of Assembly of Multidrug Efflux Pump AcrAB-ToIC
Elena B. Tikhonova et al.
CHEMISTRY & BIOLOGY (2011)
Funnel-like Hexameric Assembly of the Periplasmic Adapter Protein in the Tripartite Multidrug Efflux Pump in Gram-negative Bacteria
Yongbin Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli
Chih-Chia Su et al.
NATURE (2011)
Tackling antibiotic resistance
Karen Bush et al.
NATURE REVIEWS MICROBIOLOGY (2011)
Structure of reconstituted bacterial membrane efflux pump by cryo-electron tomography
Sylvain Trepout et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)
Accounting for conformational changes during protein-protein docking
Martin Zacharias
CURRENT OPINION IN STRUCTURAL BIOLOGY (2010)
Relation between Free Energy Landscapes of Proteins and Dynamics
Gia G. Maisuradze et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2010)
Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa
Gaby Sennhauser et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Free-energy landscape, principal component analysis, and structural clustering to identify representative conformations from molecular dynamics simulations: The myoglobin case
Elena Papaleo et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2009)
Tracking Membrane Protein Association in Model Membranes
Myriam Reffay et al.
PLOS ONE (2009)
The assembled structure of a complete tripartite bacterial multidrug efflux pump
Martyn F. Symmons et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Kinetic control of TolC recruitment by multidrug efflux complexes
Elena B. Tikhonova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A minimal sequence code for switching protein structure and function
Patrick A. Alexander et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations
In Suk Joung et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2008)
Assembly and channel opening in a bacterial drug efflux machine
Vassiliy N. Bavro et al.
MOLECULAR CELL (2008)
Ensemble docking of multiple protein structures: Considering protein structural variations in molecular docking
Sheng-You Huang et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Statistical potential for assessment and prediction of protein structures
Min-Yi Shen et al.
PROTEIN SCIENCE (2006)
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Satoshi Murakami et al.
NATURE (2006)
Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism
Markus A. Seeger et al.
SCIENCE (2006)
Flexibility in a drug transport accessory protein: Molecular dynamics simulations of MexA
Loredana Vaccaro et al.
BIOPHYSICAL JOURNAL (2006)
Conformational flexibility in the multidrug efflux system protein AcrA
J Mikolosko et al.
STRUCTURE (2006)
Interaction of the MexA and MexB components of the MexAB-OprM multidrug efflux system of Pseudomonas aeruginosa:: Identification of MexA extragenic suppressors of a T578I mutation in MexB
D Nehme et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Differential impact of MexB mutations on substrate selectivity of the MexAB-OprM multidrug efflux pump of Pseudomonas aeruginosa
JK Middlemiss et al.
JOURNAL OF BACTERIOLOGY (2004)
Structure of the periplasmic component of a bacterial drug efflux pump
MK Higgins et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa
H Akama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Assembly of the MexAB-OprM multidrug efflux system of Pseudomonas aeruginosa:: Identification and characterization of mutations in mexA compromising MexA multimerization and interaction with MexB
D Nehme et al.
JOURNAL OF BACTERIOLOGY (2004)
pH-induced conformational changes of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system
H Ip et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Protein-protein docking with a reduced protein model accounting for side-chain flexibility
M Zacharias
PROTEIN SCIENCE (2003)
The AcrB multidrug transporter plays a major role in high-level fluoroquinolone resistance in Salmonella enterica serovar typhimurium phage type DT204
S Baucheron et al.
MICROBIAL DRUG RESISTANCE (2002)
Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominately by two large periplasmic loops
CA Elkins et al.
JOURNAL OF BACTERIOLOGY (2002)
Crystal structure of bacterial multidrug efflux transporter AcrB
S Murakami et al.
NATURE (2002)
Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
V Koronakis et al.
NATURE (2000)
Contributions of the AmpC β-lactamase and the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to β-lactams
A Mazzariol et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)