4.6 Article

Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Cancer Statistics, 2021

Rebecca L. Siegel et al.

Summary: Every year, the American Cancer Society projects the numbers of new cancer cases and deaths in the United States, with the latest data showing a significant decline in lung cancer mortality, while prostate cancer mortality has plateaued and breast and colorectal cancer mortality have slowed. Improvements in treatment have accelerated progress against lung cancer, leading to a record drop in overall cancer mortality.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

First-in-Class Selective HDAC6 Inhibitor (ACY-1215) Has a Highly Favorable Safety Profile in Patients with Relapsed and Refractory Lymphoma

Jennifer E. Amengual et al.

Summary: ACY-1215, an oral selective HDAC6 inhibitor, was safe in patients with relapsed and refractory lymphoid malignancies and led to disease stabilization in half of the evaluable patients.

ONCOLOGIST (2021)

Article Pharmacology & Pharmacy

HDAC6 as privileged target in drug discovery: A perspective

Sravani Pulya et al.

Summary: HDAC6, a class IIB HDAC isoenzyme, plays a unique role in regulating various disease states through targeting non-histone proteins. While several HDAC6 inhibitors have been developed, more work is needed to identify highly selective and potent inhibitors. Targeting HDAC6 has been found to be effective for therapeutic purposes in different disease conditions.

PHARMACOLOGICAL RESEARCH (2021)

Article Medicine, General & Internal

Hepatocellular carcinoma

Josep M. Llovet et al.

Summary: Liver cancer, particularly hepatocellular carcinoma (HCC), poses a significant global health challenge with rising incidence projected to exceed 1 million cases by 2025. Infection by hepatitis B and C viruses remains a major risk factor for HCC, while non-alcoholic steatohepatitis is emerging as a more common risk factor in Western countries. Advances in systemic therapies for HCC, including immunotherapies and targeted therapies, are expected to revolutionize the management of this disease.

NATURE REVIEWS DISEASE PRIMERS (2021)

Article Biochemistry & Molecular Biology

MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network

Rana Elkholi et al.

MOLECULAR CELL (2019)

Review Biochemistry & Molecular Biology

SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis

Yuanzhen Ma et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Article Cell Biology

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition

Ashley L. Kalinski et al.

JOURNAL OF CELL BIOLOGY (2019)

Article Cell Biology

p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer

Xiao-Yu Yan et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)

Article Multidisciplinary Sciences

Promotion of growth factor signaling as a critical function of β-catenin during HCC progression

Eunsun Kim et al.

NATURE COMMUNICATIONS (2019)

Review Cell Biology

Hypoxia-Modified Cancer Cell Metabolism

Wafaa Al Tameemi et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)

Review Cell Biology

Cell-Autonomous Metabolic Reprogramming in Hypoxia

Luana Schito et al.

TRENDS IN CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells

Kai Liu et al.

MOLECULAR CELL (2017)

Review Oncology

Expanding perspectives on the significance of mitophagy in cancer

Lauren E. Drake et al.

SEMINARS IN CANCER BIOLOGY (2017)

Review Biochemistry & Molecular Biology

Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities

Roel Nusse et al.

Article Biochemistry & Molecular Biology

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy

Davor Ivankovic et al.

JOURNAL OF NEUROCHEMISTRY (2016)

Review Biochemistry & Molecular Biology

The mitochondrial pyruvate carrier in health and disease: To carry or not to carry?

Tom Bender et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)

Article Biochemistry & Molecular Biology

HDAC6 inhibition induces mitochondrial fusion, autophagic flux and reduces diffuse mutant huntingtin in striatal neurons

Pedro Guedes-Dias et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)

Article Biochemistry & Molecular Biology

The complex crosstalk between mitochondria and the nucleus: What goes in between?

Umut Cagin et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)

Review Biochemistry & Molecular Biology

The pathways of mitophagy for quality control and clearance of mitochondria

G. Ashrafi et al.

CELL DEATH AND DIFFERENTIATION (2013)

Article Biochemistry & Molecular Biology

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

Katy J. Petherick et al.

EMBO JOURNAL (2013)

Article Cell Biology

TCF/LEFs and Wnt Signaling in the Nucleus

Ken M. Cadigan et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Article Cell Biology

HDAC6 a new cellular stress surveillance factor

Patrick Matthias et al.

CELL CYCLE (2008)

Article Biochemistry & Molecular Biology

HDAC6 is required for epidermal growth factor-induced β-catenin nuclear localization

Yu Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Cell Biology

Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia

Abderrahmane Kaidi et al.

NATURE CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

Functional interaction between β-catenin and FOXO in oxidative stress signaling

MAG Essers et al.

SCIENCE (2005)

Article Biochemistry & Molecular Biology

Acetylation of β-catenin by p300 regulates β-catenin-Tcf4 interaction

L Lévy et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)