相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Genetic Mutations of Pancreatic Cancer and Genetically Engineered Mouse Models
Yuriko Saiki et al.
CANCERS (2022)
Autophagy as a therapeutic target in pancreatic cancer
Max Piffoux et al.
BRITISH JOURNAL OF CANCER (2021)
Regulation and function of autophagy in pancreatic cancer
Jingbo Li et al.
AUTOPHAGY (2021)
Cancer Statistics, 2021
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
Xiphias Ge Zhu et al.
CELL METABOLISM (2021)
Targeting Redox Metabolism in Pancreatic Cancer
Nadine Abdel Hadi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
TP53INP1 exerts neuroprotection under ageing and Parkinson's disease-related stress condition
Emilie Dinh et al.
CELL DEATH & DISEASE (2021)
Perioperative Predictors of Early Recurrence for Resectable and Borderline-Resectable Pancreatic Cancer
Masafumi Imamura et al.
CANCERS (2021)
Mito-Bomb: Targeting Mitochondria for Cancer Therapy
Xiaolu Guo et al.
ADVANCED MATERIALS (2021)
Advances in the management of pancreatic ductal adenocarcinoma
Grainne M. O'Kane et al.
CANADIAN MEDICAL ASSOCIATION JOURNAL (2021)
Overcoming chemoresistance by targeting reprogrammed metabolism: the Achilles' heel of pancreatic ductal adenocarcinoma
Abudureyimu Tuerhong et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2021)
The biological underpinnings of therapeutic resistance in pancreatic cancer
Gregory L. Beatty et al.
GENES & DEVELOPMENT (2021)
Cell death in pancreatic cancer: from pathogenesis to therapy
Xin Chen et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)
Autophagy is a major metabolic regulator involved in cancer therapy resistance
Laura Poillet-Perez et al.
CELL REPORTS (2021)
Genomic Heterogeneity of Pancreatic Ductal Adenocarcinoma and Its Clinical Impact
Maria Laura Gutierrez et al.
CANCERS (2021)
Cancer metabolism: looking forward
Inmaculada Martinez-Reyes et al.
NATURE REVIEWS CANCER (2021)
Autophagy in tumour immunity and therapy
Houjun Xia et al.
NATURE REVIEWS CANCER (2021)
Autophagy and mitophagy in cancer metabolic remodelling
Fabio Ferro et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)
From state-of-the-art treatments to novel therapies for advanced-stage pancreatic cancer
Christopher Nevala-Plagemann et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2020)
Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer
Matthieu Lacroix et al.
MOLECULAR METABOLISM (2020)
Cancer statistics, 2020
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2020)
Borderline or locally advanced pancreatic adenocarcinoma: A single center experience on the FOLFIRINOX induction regimen
Jonathan Garnier et al.
EJSO (2020)
Metabolism of pancreatic cancer: paving the way to better anticancer strategies
Cheng Qin et al.
MOLECULAR CANCER (2020)
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution
Michelle Chan-Seng-Yue et al.
NATURE GENETICS (2020)
A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients
Herbert J. Zeh et al.
CLINICAL CANCER RESEARCH (2020)
Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics
Alia Ghoneum et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Metabolic reprogramming and cancer progression
Brandon Faubert et al.
SCIENCE (2020)
The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside
Kivanc Gorgulu et al.
CELLS (2020)
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
Keisuke Yamamoto et al.
NATURE (2020)
Mitochondrial Metabolism in PDAC: From Better Knowledge to New Targeting Strategies
Gabriela Reyes-Castellanos et al.
BIOMEDICINES (2020)
Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
Claudie Bosc et al.
NATURE COMMUNICATIONS (2020)
Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells
Sandra Valle et al.
NATURE COMMUNICATIONS (2020)
The Tumor Microenvironment of Pancreatic Cancer
Eva Karamitopoulou
CANCERS (2020)
Targeting Mitochondrial Complex I Overcomes Chemoresistance in High OXPHOS Pancreatic Cancer
Rawand Masoud et al.
CELL REPORTS MEDICINE (2020)
Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response
Laura Poillet-Perez et al.
NATURE CANCER (2020)
Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells
Yihua Wang et al.
AUTOPHAGY (2019)
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Kirsten L. Bryant et al.
NATURE MEDICINE (2019)
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
Conan G. Kinsey et al.
NATURE MEDICINE (2019)
Molecular subtypes of pancreatic cancer
Eric A. Collisson et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)
Blocking autophagy to starve pancreatic cancer
Kirsten L. Bryant et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer A Phase 2 Randomized Clinical Trial
Thomas B. Karasic et al.
JAMA ONCOLOGY (2019)
Role of tumor and host autophagy in cancer metabolism
Laura Poillet-Perez et al.
GENES & DEVELOPMENT (2019)
Mechanisms and Implications of Metabolic Heterogeneity in Cancer
Jiyeon Kim et al.
CELL METABOLISM (2019)
Targeting Autophagy in Cancer: Recent Advances and Future Directions
Ravi K. Amaravadi et al.
CANCER DISCOVERY (2019)
Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice
Kivanc Goerguelue et al.
GASTROENTEROLOGY (2019)
TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling
Bochra Zidi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Systemic treatment of pancreatic cancer revisited
Michel Ducreux et al.
SEMINARS IN ONCOLOGY (2019)
Role of the tumor microenvironment in pancreatic cancer
Takashi Murakami et al.
ANNALS OF GASTROENTEROLOGICAL SURGERY (2019)
Dual role of autophagy in hallmarks of cancer
Shikha Satendra Singh et al.
ONCOGENE (2018)
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
Mario Mauthe et al.
AUTOPHAGY (2018)
Trends in pancreatic adenocarcinoma incidence and mortality in the United States in the last four decades; a SEER-based study
Anas M. Saad et al.
BMC CANCER (2018)
Cargo recognition and degradation by selective autophagy
Damian Gatica et al.
NATURE CELL BIOLOGY (2018)
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting
Elisabeth Wyart et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and nonautonomous Mechanisms
Annan Yang et al.
CANCER DISCOVERY (2018)
Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features
Francesco Puleo et al.
GASTROENTEROLOGY (2018)
Autophagy maintains tumour growth through circulating arginine
Laura Poillet-Perez et al.
NATURE (2018)
FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer
T. Conroy et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes
Andrew McGuigan et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2018)
Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice
Sho Endo et al.
GASTROENTEROLOGY (2017)
Establishment and characterization of a novel murine model of pancreatic cancer cachexia
Katherine A. Michaelis et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2017)
Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis
Nicolas Chuvin et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2017)
Phase I study of a chloroquine-gemcitabine combination in patients with metastatic or unresectable pancreatic cancer
Panagiotis Samaras et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2017)
Putting p53 in Context
Edward R. Kastenhuber et al.
CELL (2017)
Targeting autophagy in cancer
Jean M. Mulcahy Levy et al.
NATURE REVIEWS CANCER (2017)
Mitochondria and cancer chemoresistance
Flora Guerra et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2017)
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
Christina H. Eng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The Emerging Hallmarks of Cancer Metabolism
Natalya N. Pavlova et al.
CELL METABOLISM (2016)
Pancreatic cancer microenvironment, to target or not to target?
Ryan M. Carr et al.
EMBO MOLECULAR MEDICINE (2016)
Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2016)
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
Cristovao M. Sousa et al.
NATURE (2016)
Genomic analyses identify molecular subtypes of pancreatic cancer
Peter Bailey et al.
NATURE (2016)
Fundamentals of cancer metabolism
Ralph J. DeBerardinis et al.
SCIENCE ADVANCES (2016)
Autophagy is induced in the skeletal muscle of cachectic cancer patients
Zaira Aversa et al.
SCIENTIFIC REPORTS (2016)
Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma
Brian A. Boone et al.
ANNALS OF SURGICAL ONCOLOGY (2015)
The stress protein TP53INP1 plays a tumor suppressive role by regulating metabolic homeostasis
Houda Saadi et al.
BIOCHIMIE (2015)
Autophagy in malignant transformation and cancer progression
Lorenzo Galluzzi et al.
EMBO JOURNAL (2015)
Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1
Marion Seillier et al.
EMBO MOLECULAR MEDICINE (2015)
Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine
Ming-Chen Yang et al.
MOLECULAR CANCER (2015)
Targeting mitochondria metabolism for cancer therapy
Samuel E. Weinberg et al.
NATURE CHEMICAL BIOLOGY (2015)
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress
Laura Antonucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up
Rushika M. Perera et al.
CANCER DISCOVERY (2015)
Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy
Laura Poillet-Perez et al.
REDOX BIOLOGY (2015)
Inhibition of autophagy attenuates pancreatic cancer growth independent of TP53/TRP53 status
Annan Yang et al.
AUTOPHAGY (2014)
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib et al.
CANCER RESEARCH (2014)
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
Andrea Viale et al.
NATURE (2014)
Phase II and Pharmacodynamic Study of Autophagy Inhibition Using Hydroxychloroquine in Patients With Metastatic Pancreatic Adenocarcinoma
Brian M. Wolpin et al.
ONCOLOGIST (2014)
Targeting Mitochondrial Metabolism by Inhibiting Autophagy in BRAF-Driven Cancers
Anne M. Strohecker et al.
CANCER DISCOVERY (2014)
Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
Annan Yang et al.
CANCER DISCOVERY (2014)
Oxidative Stress Induced by Inactivation of TP53INP1 Cooperates with KrasG12D to Initiate and Promote Pancreatic Carcinogenesis in the Murine Pancreas
Talal Al Saati et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Autophagy-Mediated Tumor Promotion
Jessie Yanxiang Guo et al.
CELL (2013)
Mutant TP53 in Duodenal Samples of Pancreatic Juice From Patients With Pancreatic Cancer or High-Grade Dysplasia
Mitsuro Kanda et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2013)
Genetic Alterations Associated With Progression From Pancreatic Intraepithelial Neoplasia to Invasive Pancreatic Tumor
Stephen J. Murphy et al.
GASTROENTEROLOGY (2013)
Exploiting the bad eating habits of Ras-driven cancers
Eileen White
GENES & DEVELOPMENT (2013)
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2013)
Histopathologic assessment of pancreatic cancer: Does one size fit all?
Michelle D. Reid et al.
JOURNAL OF SURGICAL ONCOLOGY (2013)
p53 status determines the role of autophagy in pancreatic tumour development
Mathias T. Rosenfeldt et al.
NATURE (2013)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia
G. Shi et al.
ONCOGENE (2013)
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
Jurre J. Kamphorst et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors
Anne M. Strohecker et al.
CANCER DISCOVERY (2013)
TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death
M. Seillier et al.
CELL DEATH AND DIFFERENTIATION (2012)
Deconvoluting the context-dependent role for autophagy in cancer
Eileen White
NATURE REVIEWS CANCER (2012)
Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
Robin Mathew et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)
Pancreatic cancers require autophagy for tumor growth
Shenghong Yang et al.
GENES & DEVELOPMENT (2011)
The dynamic nature of autophagy in cancer
Alec C. Kimmelman
GENES & DEVELOPMENT (2011)
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2011)
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
Rebecca Lock et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
Thierry Conroy et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
R. Kang et al.
CELL DEATH AND DIFFERENTIATION (2010)
Role of autophagy in suppression of inflammation and cancer
Eileen White et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Tumor Protein 53-Induced Nucear Protein 1 Is a Major Mediator of p53 Antioxidant Function
Carla E. Cano et al.
CANCER RESEARCH (2009)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
Hye Seung Jung et al.
CELL METABOLISM (2008)
Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development
Meritxell Gironella et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Pancreatic adenocarcinoma: update on the surgical pathology of carcinomas of ductal origin and PanINs
Ralph H. Hruban et al.
MODERN PATHOLOGY (2007)
Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis
M Erkan et al.
ONCOGENE (2005)
Intrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancer
M Akada et al.
CLINICAL CANCER RESEARCH (2005)
分享论文
