相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Overexpression of β-Arrestins inhibits proliferation and motility in triple negative breast cancer cells
Saber Yari Bostanabad et al.
SCIENTIFIC REPORTS (2021)
The GRKs Reactome: Role in Cell Biology and Pathology
Preeti Kumari Chaudhary et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
α-Arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis
Aleena K. S. Arakaki et al.
JOURNAL OF CELL SCIENCE (2021)
GPCR Partners as Cancer Driver Genes: Association with PH-Signal Proteins in a Distinctive Signaling Network
Jeetendra Kumar Nag et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
G Protein-coupled Receptors in Cancer Stem Cells
Yuhong Jiang et al.
CURRENT PHARMACEUTICAL DESIGN (2020)
Probing the mutational landscape of regulators of G protein signaling proteins in cancer
Vincent DiGiacomo et al.
SCIENCE SIGNALING (2020)
The current status of anti-GPCR drugs against different cancers
Sana Usman et al.
JOURNAL OF PHARMACEUTICAL ANALYSIS (2020)
Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets
Nicholas G. Paciaroni et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2020)
Association between Angiotensin-Converting Enzyme Inhibitors and Lung Cancer-A Nationwide, Population-Based, Propensity Score-Matched Cohort Study
Shih-Yi Lin et al.
CANCERS (2020)
The Network of Angiotensin Receptors in Breast Cancer
Filippo Acconcia
CELLS (2020)
β-arrestin 2 Is a Prognostic Factor for Survival of Ovarian Cancer Patients Upregulating Cell Proliferation
Bastian Czogalla et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
G Protein-Coupled receptors and heterotrimeric G proteins as cancer drivers
Nadia Arang et al.
FEBS LETTERS (2020)
PAR1&2 driven placenta EVT invasion act via LRP5/6 as coreceptors
Sorina Grisaru-Granovsky et al.
FASEB JOURNAL (2020)
The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion (vol 31, pg 4279, 2012)
K. J. Jeong et al.
ONCOGENE (2019)
Direct targeting of Gαq and Gα11 oncoproteins in cancer cells
Suvi Annala et al.
SCIENCE SIGNALING (2019)
New Routes in GPCR/β-Arrestin-Driven Signaling in Cancer Progression and Metastasis
Anna Bagnato et al.
FRONTIERS IN PHARMACOLOGY (2019)
Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy
Victoria Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma
Zhaoming Li et al.
NATURE COMMUNICATIONS (2019)
RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells (vol 8, 653, 2018)
Nouar Qutob et al.
SCIENTIFIC REPORTS (2019)
The role and mechanism of β-arrestins in cancer invasion and metastasis
Qing Song et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
The expression of protease-activated receptors in esophageal carcinoma cells: the relationship between changes in gene expression and cell proliferation, apoptosis in vitro and growing ability in vivo
Ping Jiang et al.
CANCER CELL INTERNATIONAL (2018)
Regulatory Role of G Protein-coupled Receptors in Pancreatic Cancer Development and Progression
Hildegard M. Schuller
CURRENT MEDICINAL CHEMISTRY (2018)
GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells
Shu Z. Wiley et al.
FASEB JOURNAL (2018)
GPCRs in Cancer: Protease-Activated Receptors, Endocytic Adaptors and Signaling
Aleena K. S. Arakaki et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Biased signalling: from simple switches to allosteric microprocessors
Jeffrey S. Smith et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
G protein-coupled receptor kinases (GRKs) in tumorigenesis and cancer progression: GPCR regulators and signaling hubs
Laura Nogues et al.
SEMINARS IN CANCER BIOLOGY (2018)
GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets
Paul A. Insel et al.
FRONTIERS IN PHARMACOLOGY (2018)
Targeting nucleotide exchange to inhibit constitutively active G protein a subunits in cancer cells
Michael D. Onken et al.
SCIENCE SIGNALING (2018)
A polymorphism in the fatty acid desaturase-2 gene is associated with the arachidonic acid metabolism in pigs
Sofia Gol et al.
SCIENTIFIC REPORTS (2018)
Angiotensin converting enzyme inhibitors and risk of lung cancer: population based cohort study
Blanaid M. Hicks et al.
BMJ-BRITISH MEDICAL JOURNAL (2018)
Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells
Fang Hao et al.
MOLECULAR CANCER RESEARCH (2017)
MAPK and Hippo signaling pathways crosstalk via the RAF-1/MST-2 interaction in malignant melanoma
Ruizheng Feng et al.
ONCOLOGY REPORTS (2017)
Loss of β-arrestin-2 and Activation of CXCR2 Correlate with Lymph Node Metastasis in Non-small Cell Lung Cancer
Lei Cong et al.
JOURNAL OF CANCER (2017)
GPCRs: Emerging anti-cancer drug targets
Ainhoa Nieto Gutierrez et al.
CELLULAR SIGNALLING (2017)
Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development
Christine Dethlefsen et al.
CANCER RESEARCH (2017)
RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma
Xu Chen et al.
CANCER CELL (2017)
Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells
M. O'Hayre et al.
ONCOGENE (2016)
Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer
D. C. Borcherding et al.
ONCOGENE (2016)
Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma
Ugur M. Ayturk et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
G protein-coupled receptors as promising cancer targets
Ying Liu et al.
CANCER LETTERS (2016)
The G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis
Rohit Rao et al.
CELL CYCLE (2016)
Nephrogenic syndrome of inappropriate antidiuresis secondary to an activating mutation in the arginine vasopressin receptor AVPR2
Andrew S. Powlson et al.
CLINICAL ENDOCRINOLOGY (2016)
GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR
H. Zhou et al.
CELL DEATH & DISEASE (2016)
G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells
Caihong Zhou et al.
ONCOTARGET (2016)
RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation
Jianqi Yang et al.
ONCOTARGET (2016)
Activation of GRP/GRP-R signaling contributes to castration-resistant prostate cancer progression
Jingbo Qiao et al.
ONCOTARGET (2016)
Down-regulation of β-arrestin2 promotes tumour invasion and indicates poor prognosis of hepatocellular carcinoma
Wu-Yi Sun et al.
SCIENTIFIC REPORTS (2016)
Gβγ Pathways in Cell Polarity and Migration Linked to Oncogenic GPCR Signaling: Potential Relevance in Tumor Microenvironment
Jose Vazquez-Prado et al.
MOLECULAR PHARMACOLOGY (2016)
G Protein-Coupled Receptors in Cancer
Rachel Bar-Shavit et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
GPCR dimerization in brainstem nuclei contributes to the development of hypertension
Gwo-Ching Sun et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?
G. O'Callaghan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Alternative Wnt Signaling Activates YAP/TAZ
Hyun Woo Park et al.
CELL (2015)
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
Fa-Xing Yu et al.
CELL (2015)
Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation
Rui Gong et al.
CELL RESEARCH (2015)
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling
Graeme M. Birdsey et al.
DEVELOPMENTAL CELL (2015)
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
Toshiro Moroishi et al.
GENES & DEVELOPMENT (2015)
Lysophosphatidic Acid Initiates Epithelial to Mesenchymal Transition and Induces β-Catenin-mediated Transcription in Epithelial Ovarian Carcinoma
Rebecca J. Burkhalter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Captopril-polyethyleneimine conjugate modified gold nanoparticles for co-delivery of drug and gene in anti-angiogenesis breast cancer therapy
Manhong Li et al.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2015)
β-Arrestin2 Contributes to Cell Viability and Proliferation via the Down-Regulation of FOXO1 in Castration-Resistant Prostate Cancer
Xiaolu Duan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2015)
The G protein-coupled receptor P2RY8 and follicular dendritic cells promote germinal center confinement of B cells, whereas S1PR3 can contribute to their dissemination
Jagan R. Muppidi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Pelvic organ prolapse is associated with alteration of sphingosine-1-phosphate/Rho-kinase signalling pathway in human vaginal wall
S. H. Rhee et al.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2015)
Blockade of vascular endothelial growth factor-A/receptor 2 exhibits a protective effect on angiotensin-II stimulated podocytes
Xiangchun Liu et al.
MOLECULAR MEDICINE REPORTS (2015)
Inactivation of a Gαs-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis
Ramiro Iglesias-Bartolome et al.
NATURE CELL BIOLOGY (2015)
Angiotensin-converting enzyme (ACE) inhibitory potential of standardized Mucuna pruriens seed extract
Sushil Kumar Chaudhary et al.
PHARMACEUTICAL BIOLOGY (2015)
N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias
Antonio G. Soto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Lysophosphatidic acid receptor (LPAR) modulators: The current pharmacological toolbox
Sabin Llona-Minguez et al.
PROGRESS IN LIPID RESEARCH (2015)
Tissue-based map of the human proteome
Mathias Uhlen et al.
SCIENCE (2015)
PH motifs in PAR1&2 endow breast cancer growth
A. Kancharla et al.
NATURE COMMUNICATIONS (2015)
β-Arrestin1 enhances hepatocellular carcinogenesis through inflammation-mediated Akt signalling
Yidong Yang et al.
NATURE COMMUNICATIONS (2015)
MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
Zhipeng Meng et al.
NATURE COMMUNICATIONS (2015)
Signal Transduction in Cancer
Richard Sever et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)
Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers
Yusuke Oku et al.
FEBS OPEN BIO (2015)
Activation of S1P1 Receptor Regulates PI3K/Akt/FoxO3a Pathway in Response to Oxidative Stress in PC12 Cells
Fatemeh Safarian et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2015)
Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status
Jon Lidfeldt et al.
PLOS ONE (2015)
FAK is a critical regulator of neuroblastoma liver metastasis
Sora Lee et al.
Oncotarget (2015)
The G Protein-Biased kappa-Opioid Receptor Agonist RB-64 Is Analgesic with a Unique Spectrum of Activities In Vivo
Kate L. White et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
The impact of activated p-AKT expression on clinical outcomes in diffuse large B-cell lymphoma: a clinicopathological study of 262 cases
J. Y. Hong et al.
ANNALS OF ONCOLOGY (2014)
A chitosan-graft-PEI-candesartan conjugate for targeted co-delivery of drug and gene in anti-angiogenesis cancer therapy
Xiuli Bao et al.
BIOMATERIALS (2014)
Discovery of novel non-carboxylic acid 5-amino-4-cyanopyrazole derivatives as potent and highly selective LPA1R antagonists
Achyutharao Sidduri et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Mutant Gq/11 Promote Uveal Melanoma Tumorigenesis by Activating YAP
Fa-Xing Yu et al.
CANCER CELL (2014)
Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
Xiaodong Feng et al.
CANCER CELL (2014)
The Angiotensin II type 1 receptor blocker candesartan suppresses proliferation and fibrosis in gastric cancer
Mitsuyoshi Okazaki et al.
CANCER LETTERS (2014)
Novel insights into G protein and G protein-coupled receptor signaling in cancer
Morgan O'Hayre et al.
CURRENT OPINION IN CELL BIOLOGY (2014)
βArrestin1 Regulates the Guanine Nucleotide Exchange Factor RasGRF2 Expression and the Small GTPase Rac- mediated Formation of Membrane Protrusion and Cell Motility
Xiaojie Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
In Vitro modeling of angiotensin-converting enzyme inhibitor's absorption with chromatographic retention data and selected molecular descriptors
Jadranka Odovic et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2014)
Individual variation of human S1P1 coding sequence leads to heterogeneity in receptor function and drug interactions
Hideru Obinata et al.
JOURNAL OF LIPID RESEARCH (2014)
Thematic Review Series: Lysophospholipids and their Receptors LPA receptor signaling: pharmacology, physiology, and pathophysiology
Yun C. Yung et al.
JOURNAL OF LIPID RESEARCH (2014)
Replacement of short segments within transmembrane domains of MC2R disrupts retention signal
Davids Fridmanis et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2014)
Sphingosine 1-phosphate increases an intracellular Ca2+ concentration via S1P3 receptor in cultured vascular smooth muscle cells
Kazumi Fujii et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2014)
Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma
Jagan R. Muppidi et al.
NATURE (2014)
Metabolic control of YAP and TAZ by the mevalonate pathway
Giovanni Sorrentino et al.
NATURE CELL BIOLOGY (2014)
The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma
Xuelian He et al.
NATURE MEDICINE (2014)
Development of allosteric modulators of GPCRs for treatment of CNS disorders
Hilary Highfield Nickols et al.
NEUROBIOLOGY OF DISEASE (2014)
In Silico Analysis of Missense Mutations in LPAR6 Reveals Abnormal Phospholipid Signaling Pathway Leading to Hypotrichosis
Syed Irfan Raza et al.
PLOS ONE (2014)
G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion
Michael E. Feigin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Surveillance and quality improvement in the United Kingdom: Is there a meeting point?
Alexander J. Fowler et al.
SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND (2014)
The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo
W. Wei et al.
CELL DEATH & DISEASE (2014)
Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs
Chong Wang et al.
NATURE COMMUNICATIONS (2014)
RHO Mutations (p.W126L and p.A346P) in Two Japanese Families with Autosomal Dominant Retinitis Pigmentosa
Satoshi Katagiri et al.
JOURNAL OF OPHTHALMOLOGY (2014)
Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cells
Kwang Woon Kim et al.
AUTOPHAGY (2013)
Modulators of the Sphingosine 1-phosphate receptor 1
Mariangela Urbano et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
Ryan D. Morin et al.
BLOOD (2013)
Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy
James V. Alvarez et al.
CANCER CELL (2013)
Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway
Virginie Follin-Arbelet et al.
CANCER LETTERS (2013)
GPR116, an Adhesion G-Protein-Coupled Receptor, Promotes Breast Cancer Metastasis via the Gaq-p63RhoGEF-Rho GTPase Pathway
Xiaolong Tang et al.
CANCER RESEARCH (2013)
Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression
Biswanath Maity et al.
CARCINOGENESIS (2013)
Hereditary nephrogenic diabetes insipidus in Japanese patients: analysis of 78 families and report of 22 new mutations in AVPR2 and AQP2
Sei Sasaki et al.
CLINICAL AND EXPERIMENTAL NEPHROLOGY (2013)
cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes
Minchul Kim et al.
EMBO JOURNAL (2013)
A Novel Experimental Strategy to Assess the Metabolic Effects of Selective Activation of a Gq-Coupled Receptor in Hepatocytes In Vivo
Jian Hua Li et al.
ENDOCRINOLOGY (2013)
Sphingosine 1-phosphate receptor agonists: a patent review (2010-2012)
Edward Roberts et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2013)
Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis
Michael E. Feigin
FEBS JOURNAL (2013)
Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation
Fa-Xing Yu et al.
GENES & DEVELOPMENT (2013)
Elevated gastrin-releasing peptide receptor mRNA expression in buccal mucosa: association with head and neck squamous cell carcinoma
Ann Marie Egloff et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2013)
A multicenter phase II trial of gemcitabine and candesartan combination therapy in patients with advanced pancreatic cancer: GECA2
Yousuke Nakai et al.
INVESTIGATIONAL NEW DRUGS (2013)
Family of melanocortin receptor (MCR) genes in mammals-mutations, polymorphisms and phenotypic effects
M. Switonski et al.
JOURNAL OF APPLIED GENETICS (2013)
Llama-derived Single Variable Domains (Nanobodies) Directed against Chemokine Receptor CXCR7 Reduce Head and Neck Cancer Cell Growth in Vivo
David Maussang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation
Constantinos M. Mikelis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Pseudopodial and β-arrestin-interacting proteomes from migrating breast cancer cells upon PAR2 activation
Nikolaos Parisis et al.
JOURNAL OF PROTEOMICS (2013)
RGS expression in cancer: oncomining the cancer microarray data
Nan Sethakorn et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2013)
Lysophosphatidic acid activates β-catenin/T cell factor signaling, which contributes to the suppression of apoptosis in H19-7 cells
Yuanjie Sun et al.
MOLECULAR MEDICINE REPORTS (2013)
Molecular signatures of G-protein-coupled receptors
A. J. Venkatakrishnan et al.
NATURE (2013)
Sturge-Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ
Matthew D. Shirley et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling
L. Rosano et al.
ONCOGENE (2013)
Integrin β1 is critical for gastrin-releasing peptide receptor-mediated neuroblastoma cell migration and invasion
Sora Lee et al.
SURGERY (2013)
The structure and function of the S1P1 receptor
Catherine O'Sullivan et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Regulation of the Hippo pathway and implications for anticancer drug development
Hyun Woo Park et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
TF/FVIIa/PAR2 promotes cell proliferation and migration via PKCα and ERK-dependent c-Jun/AP-1 pathway in colon cancer cell line SW620
Lichao Hu et al.
TUMOR BIOLOGY (2013)
Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy
Alessandro Cannavo et al.
FRONTIERS IN PHYSIOLOGY (2013)
Endothelin 1 in cancer: biological implications and therapeutic opportunities
Laura Rosano et al.
NATURE REVIEWS CANCER (2013)
The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer
Morgan O'Hayre et al.
NATURE REVIEWS CANCER (2013)
Genistein regulates the IL-1 beta induced activation of MAPKs in human periodontal ligament cells through G protein-coupled receptor 30
Li-Jun Luo et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)
Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo
Mayumi Komachi et al.
CANCER SCIENCE (2012)
Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
Fa-Xing Yu et al.
CELL (2012)
β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
Joseph Rosenbluh et al.
CELL (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP
Eric Miller et al.
CHEMISTRY & BIOLOGY (2012)
The many faces and functions of β-catenin
Tomas Valenta et al.
EMBO JOURNAL (2012)
G Protein-Coupled Receptor 30 Mediates Estrogen-Induced Proliferation of Primordial Germ Cells Via EGFR/Akt/β-Catenin Signaling Pathway
Chutian Ge et al.
ENDOCRINOLOGY (2012)
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
Jung-Soon Mo et al.
GENES & DEVELOPMENT (2012)
Mutations in the Planar Cell Polarity Genes CELSR1 and SCRIB are Associated with the Severe Neural Tube Defect Craniorachischisis
Alexis Robinson et al.
HUMAN MUTATION (2012)
Targeting lysophosphatidic acid receptor type 1 with Debio 0719 inhibits spontaneous metastasis dissemination of breast cancer cells independently of cell proliferation and angiogenesis
Marion David et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
p53, a Target of Estrogen Receptor (ER) α, Modulates DNA Damage-induced Growth Suppression in ER-positive Breast Cancer Cells
Crystal E. Berger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Identification of a Nuclear Localization Sequence in β-Arrestin-1 and Its Functional Implications
Crystal Zoe Hoeppner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
An Atypical Case of Familial Glucocorticoid Deficiency without Pigmentation Caused by Coexistent Homozygous Mutations in MC2R (T152K) and MC1R (R160W)
Serap Turan et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Insulin resistance induces a segmental difference in thoracic and abdominal aorta: differential expression of AT1 and AT2 receptors
Pinakin Arun Karpe et al.
JOURNAL OF HYPERTENSION (2012)
Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling
Domitille Heitzler et al.
MOLECULAR SYSTEMS BIOLOGY (2012)
Structure and dynamics of the M3 muscarinic acetylcholine receptor
Andrew C. Kruse et al.
NATURE (2012)
Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder
Josephine Elia et al.
NATURE GENETICS (2012)
The genetic landscape of mutations in Burkitt lymphoma
Cassandra Love et al.
NATURE GENETICS (2012)
The Hippo signaling pathway and stem cell biology
Azucena Ramos et al.
TRENDS IN CELL BIOLOGY (2012)
PI3K-PKB/Akt Pathway
Brian A. Hemmings et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Alternative Wnt Pathways and Receptors
Renee van Amerongen
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Mutations in the AVPR2, AVP-NPII, and AQP2 genes in Turkish patients with diabetes insipidus
Duygu Duzenli et al.
ENDOCRINE (2012)
Towards the use of cannabinoids as antitumour agents
Guillermo Velasco et al.
NATURE REVIEWS CANCER (2012)
Regulation of bombesin-stimulated cyclooxygenase-2 expression in prostate cancer cells
Xiaodong Wen et al.
BMC MOLECULAR BIOLOGY (2011)
Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis
Thierry Voisin et al.
CANCER RESEARCH (2011)
The role of peripheral gonadotropin-releasing hormone receptors in female reproduction
Bo Yu et al.
FERTILITY AND STERILITY (2011)
Decreased expression of protease-activated receptor 4 in human gastric cancer
Yong Zhang et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription
Yijun Bao et al.
JOURNAL OF BIOCHEMISTRY (2011)
A Critical Role of Gβγ in Tumorigenesis and Metastasis of Breast Cancer
Xiaoyun Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Emerging roles for the BAI1 protein family in the regulation of phagocytosis, synaptogenesis, neurovasculature, and tumor development
Sarah M. Cork et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
A novel AVPR2 missense mutation in a Chinese boy with severe inherited nephrogenic diabetes insipidus
Lingli Huang et al.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2011)
Familial glucocorticoid deficiency due to compound heterozygosity of two novel MC2R mutations
Miriam Aza-Carmona et al.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2011)
Functional Selectivity and Biased Receptor Signaling
Terry Kenakin
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement
Jesse A. Green et al.
NATURE IMMUNOLOGY (2011)
G protein-coupled receptors: novel targets for drug discovery in cancer
Rosamaria Lappano et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
The G-protein-coupled estrogen receptor GPER in health and disease
Eric R. Prossnitz et al.
NATURE REVIEWS ENDOCRINOLOGY (2011)
Molecular basis of a novel oncogenic mutation in GNAO1
M. Garcia-Marcos et al.
ONCOGENE (2011)
Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia
Jean B. Regard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Regulation of Androgen Receptor Expression Through Angiotensin II Type I Receptor in Prostate Cancer Cells
Koji Hoshino et al.
PROSTATE (2011)
A Synthetic Biology Approach Reveals a CXCR4-G13-RhoSignaling Axis Driving Transendothelial Migration of Metastatic Breast Cancer Cells
Hiroshi Yagi et al.
SCIENCE SIGNALING (2011)
Therapeutic potential of β-arrestin- and G protein-biased agonists
Erin J. Whalen et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Different Origins of Gamma Rhythm and High-Gamma Activity in Macaque Visual Cortex
Supratim Ray et al.
PLOS BIOLOGY (2011)
β-Arrestin-Dependent Actin Reorganization: Bringing the Right Players Together at the Leading Edge
Jungah Min et al.
MOLECULAR PHARMACOLOGY (2011)
Homeostatic chemokine receptors and organ-specific metastasis
Albert Zlotnik et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Improved discrimination of melanotic schwannoma from melanocytic lesions by combined morphological and GNAQ mutational analysis
Heidi V. N. Kusters-Vandevelde et al.
ACTA NEUROPATHOLOGICA (2010)
A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis
Lin Deng et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
FTY720 induces necrotic cell death and autophagy in ovarian cancer cells A protective role of autophagy
Ning Zhang et al.
AUTOPHAGY (2010)
Murrayafoline A attenuates the Wnt/beta-catenin pathway by promoting the degradation of intracellular beta-catenin proteins
Hyuk Choi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development
Florence Schaffner et al.
BLOOD (2010)
ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole
Martin Smollich et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Subtype-specific role of phospholipase C-β in bradykinin and LPA signaling through differential binding of different PDZ scaffold proteins
Jung Woong Choi et al.
CELLULAR SIGNALLING (2010)
Tyrosine Kinase Receptor Transactivation Associated to G Protein-Coupled Receptors
Vanessa Almendro et al.
CURRENT DRUG TARGETS (2010)
The Hippo Signaling Pathway in Development and Cancer
Duojia Pan
DEVELOPMENTAL CELL (2010)
A phase Ib/IIa trial to evaluate the CCK2 receptor antagonist Z-360 in combination with gemcitabine in patients with advanced pancreatic cancer
T. Meyer et al.
EUROPEAN JOURNAL OF CANCER (2010)
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
Bin Zhao et al.
GENES & DEVELOPMENT (2010)
Down-regulation of the candidate tumor suppressor gene PAR-4 is associated with poor prognosis in breast cancer
Maria Aparecida Nagai et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2010)
Association of MC1R Variants and Host Phenotypes With Melanoma Risk in CDKN2A Mutation Carriers: A GenoMEL Study
F. Demenais et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Diverse somatic mutation patterns and pathway alterations in human cancers
Zhengyan Kan et al.
NATURE (2010)
STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
Heehyoung Lee et al.
NATURE MEDICINE (2010)
Mutations in GNA11 in Uveal Melanoma.
Catherine D. Van Raamsdonk et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Preclinical anticancer activity of the specific endothelin A receptor antagonist ZD4054
James W. Growcott
ANTI-CANCER DRUGS (2009)
Regulator of G-protein signaling (RGS) proteins in cancer biology
Jillian H. Hurst et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Increased Brain Histamine H1 Receptor Binding in Patients with Anorexia Nervosa
Masahiko Yoshizawa et al.
BIOLOGICAL PSYCHIATRY (2009)
PrognoScan: a new database for meta-analysis of the prognostic value of genes
Hideaki Mizuno et al.
BMC MEDICAL GENOMICS (2009)
Role of G12 proteins in oncogenesis and metastasis
Juhi Juneja et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Gα12-Mediated Pathway Promotes Invasiveness of Nasopharyngeal Carcinoma by Modulating Actin Cytoskeleton Reorganization
Shu-Chen Liu et al.
CANCER RESEARCH (2009)
The COX-2/PGE(2) pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
Alexander Greenhough et al.
CARCINOGENESIS (2009)
Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis
Shih-Lei Lai et al.
CELL RESEARCH (2009)
Specific Antibodies Elicited by a Novel DNA Vaccine Targeting Gastrin-Releasing Peptide Inhibit Murine Melanoma Growth In Vivo
Jing Fang et al.
CLINICAL AND VACCINE IMMUNOLOGY (2009)
Lysophosphatidic acid (LPA) and its receptors
Kyoko Noguchi et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Induction of senescence by progesterone receptor-B activation in response to cAMP in ovarian cancer cells
Akira Takahashi et al.
GYNECOLOGIC ONCOLOGY (2009)
GPR30 predicts poor survival for ovarian cancer
Harriet O. Smith et al.
GYNECOLOGIC ONCOLOGY (2009)
Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase
Valerie Gratio et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Local angiotensin II-generation in human gastric cancer: Correlation with tumor progression through the activation of ERK1/2, NF-κB and survivin
Jun Kinoshita et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2009)
Mechanisms of estrogen signaling and gene expression via GPR30
Eric R. Prossnitz et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
Catherine D. Van Raamsdonk et al.
NATURE (2009)
OPINION Is NF-κB a good target for cancer therapy? Hopes and pitfalls
Veronique Baud et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
The gep oncogenes, Gα12 and Gα13, upregulate the transforming growth factor-β1 gene
S. J. Lee et al.
ONCOGENE (2009)
Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration
S. Su et al.
ONCOGENE (2009)
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist
Daniel R. Rhodes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Identification of βArrestin2 as a corepressor of androgen receptor signaling in prostate cancer
Vijayabaskar Lakshmikanthan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis
Laura Rosano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
S1P2 receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN
Enkhzol Malchnkhuu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Expression of AT1 and AT2 angiotensin receptors in astrocytomas is associated with poor prognosis
O. Arrieta et al.
BRITISH JOURNAL OF CANCER (2008)
Nicotinic acid: an old drug with a promising future
E. T. Bodor et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Prostate cancer, serum parathyroid hormone, and the progression of skeletal metastases
Gary G. Schwartz
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice
Henri H. Versteeg et al.
CANCER RESEARCH (2008)
GPR87 is an overexpressed G-protein coupled receptor in squamous cell carcinoma of the lung
Mathias Gugger et al.
DISEASE MARKERS (2008)
Analysis of Lysophosphatidic Acid (LPA) Receptor and LPA-Induced Endometrial Prostaglandin-Endoperoxide Synthase 2 Expression in the Porcine Uterus
Heewon Seo et al.
ENDOCRINOLOGY (2008)
被撤回的出版物: G-Protein-Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells (Retracted article. See vol. 122, pg. A42, 2014)
Lidia Albanito et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2008)
Potential role of Renin-Angiotensin-system in receptor negative breast for tumor angiogenesis cancer
D. Herr et al.
GYNECOLOGIC ONCOLOGY (2008)
Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a Gα12/13 and rho pathway
Tokuichi Iguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion
P. Arora et al.
ONCOGENE (2008)
Constitutive activation of G protein-coupled receptors and diseases: Insights into mechanisms of activation and therapeutics
Ya-Xiong Tao
PHARMACOLOGY & THERAPEUTICS (2008)
Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma
Jingbo Qiao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Functional angiotensin II type 2 receptors inhibit growth factor signaling in LNCaP and PC3 prostate cancer cell lines
L. Chow et al.
PROSTATE (2008)
New Regulators of Wnt/β-Catenin Signaling Revealed by Integrative Molecular Screening
Michael B. Major et al.
SCIENCE SIGNALING (2008)
Basal cell carcinomas: attack of the hedgehog
Ervin H. Epstein
NATURE REVIEWS CANCER (2008)
Critical regulation of CD4+ T cell survival and autoimmunity by β-arrestin 1
Yufeng Shi et al.
NATURE IMMUNOLOGY (2007)
β-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
Maria Zoudilova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Biologic functions of the G12 subfamily of heterotrimeric G proteins: Growth, migration, and Metastasis
Patrick Kelly et al.
BIOCHEMISTRY (2007)
Lysophosphatidic acid facilitates proliferation of colon cancer cells via induction of Kruppel-like factor 5
Huanchun Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness
Nicholas Young et al.
EXPERIMENTAL CELL RESEARCH (2007)
Antihypertensives as novel antineoplastics: Angiotensin-I-converting enzyme inhibitors and angiotensin II type 1 receptor blockers in pancreatic ductal adenocarcinoma
Hwyda A. Arafat et al.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2007)
Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib
Xuwan Liu et al.
EXPERIMENTAL CELL RESEARCH (2007)
GPR30: a novel indicator of poor survival for endometrial carcinoma
Harriet O. Smith et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2007)
Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer
Qing Zhang et al.
MOLECULAR CANCER THERAPEUTICS (2007)
The lysophosphatidic acid (LPA) receptors their expression and significance in epithelial ovarian neoplasms
Ping Wang et al.
GYNECOLOGIC ONCOLOGY (2007)
A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth
A. Rasola et al.
ONCOGENE (2007)
Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis
Nozomi Imai et al.
LABORATORY INVESTIGATION (2007)
G-protein-coupled receptors and cancer
Robert T. Dorsam et al.
NATURE REVIEWS CANCER (2007)
G protein coupled receptor structure and activation
Brian K. Kobilka
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells
Sowmyalakshmi Srinivasan et al.
CANCER RESEARCH (2007)
Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: A potential novel mechanism of endocrine disruption
Peter Thomas et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2006)
Targeting the Hedgehog pathway in cancer
Lee L. Rubin et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression
Edward J. Filardo et al.
CLINICAL CANCER RESEARCH (2006)
P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing axin from β-catenin
Liuqing Yang et al.
CELL (2006)
17β-Estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the G protein-coupled receptor GPR30
Adele Vivacqua et al.
MOLECULAR PHARMACOLOGY (2006)
A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion
Patrick Kelly et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Gastrin-releasing peptide and cancer
Oneel Patel et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2006)
Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways
Yingmei Liu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis
Patrick Kelly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration
D Bian et al.
ONCOGENE (2006)
Inflammatory chemokines in cancer growth and progression
BJ Rollins
EUROPEAN JOURNAL OF CANCER (2006)
Thrombin generation and the pathogenesis of cancer
Wolfram Ruf et al.
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2006)
The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells
A Vivacqua et al.
MOLECULAR ENDOCRINOLOGY (2006)
Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents
I Vergote et al.
ANNALS OF ONCOLOGY (2006)
FTY720, a fungus metabolite, inhibits in vivo growth of androgen-independent prostate cancer
CW Chua et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-β-catenin signaling axis
MD Castellone et al.
SCIENCE (2005)
A nuclear function of β-arrestin1 in GPCR signaling:: Regulation of histone acetylation and gene transcription
JH Kang et al.
CELL (2005)
Comparative genomic analysis of human and chimpanzee proteases
XS Puente et al.
GENOMICS (2005)
Antiproliferative activity of angiotensin II receptor blocker through cross-talk between stromal and epithelial prostate cancer cells
H Uemura et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells
E Malchinkhuu et al.
ONCOGENE (2005)
Prostaglandin E2 stimulates the β-catenin/T cell factor-dependent transcription in colon cancer
JY Shao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
LPA2 receptor mediates mitogenic signals in human colon cancer cells
CC Yun et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Blockade of the stromal cell-derived factor-1/CXCR4 axis attenuates in vivo tumor growth by inhibiting angiogenesis in a vascular endothelial growth factor-independent manner
B Guleng et al.
CANCER RESEARCH (2005)
Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo
A Martínez et al.
ONCOGENE (2005)
Gonadotropin-releasing hormone agonists in the treatment of prostate cancer
F Labrie et al.
ENDOCRINE REVIEWS (2005)
G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the β-catenin pathway
M Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
COX-2: A molecular target for colorectal cancer prevention
JR Brown et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Blockage of angiotensin II type I receptor decreases the synthesis of growth factors and induces apoptosis in C6 cultured cells and C6 rat glioma
O Arrieta et al.
BRITISH JOURNAL OF CANCER (2005)
Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination
T Suganuma et al.
CLINICAL CANCER RESEARCH (2005)
The genetics of susceptibility to cutaneous melanoma
JAN Bishop et al.
DRUGS OF TODAY (2005)
Trimeric G protein-dependent frizzled signaling in Drosophila
VL Katanaev et al.
CELL (2005)
FTY720 inhibits tumor growth and angiogenesis
G Schmid et al.
TRANSPLANTATION PROCEEDINGS (2005)
Phosphatidylinositol 3-kinase/Akt regulates angiotensin II-induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase-3 activity
H Ohashi et al.
CIRCULATION RESEARCH (2004)
Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5
S Usui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Renin and angiotensinogen expression and functions in growth and apoptosis of human glioblastoma
L Juillerat-Jeanneret et al.
BRITISH JOURNAL OF CANCER (2004)
Angiotensin converting enzyme inhibitors for cancer treatment?
H Lindberg et al.
ACTA ONCOLOGICA (2004)
Structural and functional characteristics of S1P receptors
T Sanchez et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both β-arrestin-1 and -2
L Ge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Inhibition of cyclooxygenase-1 and-2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells
F Spinella et al.
CLINICAL CANCER RESEARCH (2004)
Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP
S Nouet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation
TK Lee et al.
CARCINOGENESIS (2004)
The Hedgehog response network: Sensors, switches, and routers
L Lum et al.
SCIENCE (2004)
Development of high affinity camptothecin-bombesin conjugates that have targeted cytotoxicity for bombesin receptor-containing tumor cells
TW Moody et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Targeting cyclooxygenase-2 in human neoplasia: Rationale and promise
AJ Dannenberg et al.
CANCER CELL (2003)
Thrombin protease-activated receptor-1 signals through Gq- and G13-initiated MAPK cascades regulating c-Jun expression to induce cell transformation
MJ Marinissen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Preclinical evaluation of therapeutic effects of targeted cytotoxic analogs of somatostatin and bombesin on human gastric carcinomas
K Szepeshazi et al.
CANCER (2003)
Ki16425, a subtype-selective antagonist for EDG-Family lysophosphatidic acid receptors
H Ohta et al.
MOLECULAR PHARMACOLOGY (2003)
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
A Gschwind et al.
EMBO JOURNAL (2003)
Identification of a new tumor suppressor gene located at chromosome 8p21.3-22
S Seibold et al.
FASEB JOURNAL (2003)
The Wnt signaling pathway and its role in tumor development
B Lustig et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2003)
Cyclooxygenase-2:: a therapeutic target in angiogenesis
MA Iñiguez et al.
TRENDS IN MOLECULAR MEDICINE (2003)
β-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
Y Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Clinical, genetic, and functional characterization of adrenocorticotropin receptor mutations using a novel receptor assay
CE Flück et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2002)
Dissemination and growth of cancer cells in metastatic sites
AF Chambers et al.
NATURE REVIEWS CANCER (2002)
Molecular mechanism for endothelin-1-induced stress-fiber formation:: Analysis of G proteins using a mutant endothelinA receptor
Y Kawanabe et al.
MOLECULAR PHARMACOLOGY (2002)
G-protein-coupled receptor dimerization: modulation of receptor function
CD Rios et al.
PHARMACOLOGY & THERAPEUTICS (2001)
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
RA Gupta et al.
NATURE REVIEWS CANCER (2001)
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in ApcΔ716 knockout mice
M Sonoshita et al.
NATURE MEDICINE (2001)
G protein signaling from activated rat Frizzled-1 to the β-catenin-Lef-Tcf pathway
T Liu et al.
SCIENCE (2001)
Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist
Y Fujimoto et al.
FEBS LETTERS (2001)
Angiogenesis and G-protein-coupled receptors:: signals that bridge the gap
DE Richard et al.
ONCOGENE (2001)
Involvement of chemokine receptors in breast cancer metastasis
A Müller et al.
NATURE (2001)
Angiotensin AT1 and AT2 receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation
S Fujiyama et al.
CIRCULATION RESEARCH (2001)
Lysophosphatidic acid receptors
JJA Contos et al.
MOLECULAR PHARMACOLOGY (2000)
Heparin blockade of thrombin-induced smooth muscle cell migration involves inhibition of epidermal growth factor (EGF) receptor transactivation by heparin-binding EGF-like growth factor
A Kalmes et al.
CIRCULATION RESEARCH (2000)
Signaling from G protein-coupled receptors to ERK5/big MAPK 1 involves Gαq and Gα12/13 families of heterotrimeric G proteins -: Evidence for the existence of a novel Ras and Rho-independent pathway
S Fukuhara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers
G Halmos et al.
JOURNAL OF UROLOGY (2000)
分享论文
