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ONCOGENE (2012)
Transcriptional upregulation of HER2 expression in the absence of HER2 gene amplification results in cetuximab resistance that is reversed by trastuzumab treatment
Cristina Oliveras-Ferraros et al.
ONCOLOGY REPORTS (2012)
Epithelial-Mesenchymal Transition: A Hallmark in Metastasis Formation Linking Circulating Tumor Cells and Cancer Stem Cells
Magdalena Ksiazkiewicz et al.
PATHOBIOLOGY (2012)
Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression
Zhao-Qiu Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
p53 and metabolism Old player in a new game
Nirmalya Sen et al.
TRANSCRIPTION-AUSTIN (2012)
Breast cancer stem-like cells show dominant homologous recombination due to a larger S-G2 fraction
Osama Al-Assar et al.
CANCER BIOLOGY & THERAPY (2011)
Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
Katharina Schlacher et al.
CELL (2011)
Incidence and Outcome of BRCA Mutations in Unselected Patients with Triple Receptor-Negative Breast Cancer
Ana M. Gonzalez-Angulo et al.
CLINICAL CANCER RESEARCH (2011)
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition
Nam Hee Kim et al.
JOURNAL OF CELL BIOLOGY (2011)
p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
Chun-Ju Chang et al.
NATURE CELL BIOLOGY (2011)
Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM
Y. Wang et al.
ONCOGENE (2011)
Constitutive expression of γ-H2AX has prognostic relevance in triple negative breast cancer
Anika Nagelkerke et al.
RADIOTHERAPY AND ONCOLOGY (2011)
Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2
Nyam-Osor Chimge et al.
BREAST CANCER RESEARCH (2011)
BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer
Julia J. Gorski et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
Samuel F. Bunting et al.
CELL (2010)
Changes of HER2 Status in Circulating Tumor Cells Compared With the Primary Tumor During Treatment for Advanced Breast Cancer
Elisabetta Munzone et al.
CLINICAL BREAST CANCER (2010)
Monitoring Drug-Induced γH2AX as a Pharmacodynamic Biomarker in Individual Circulating Tumor Cells
Lihua H. Wang et al.
CLINICAL CANCER RESEARCH (2010)
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine
Barbara van Loon et al.
DNA REPAIR (2010)
TNFalpha Up-Regulates SLUG Via the NF-kappaB/HIF1alpha Axis, Which Imparts Breast Cancer Cells With a Stem Cell-Like Phenotype
Gianluca Storci et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
Peter Bouwman et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Clinical relevance of the triple-negative breast cancer concept: Genetic basis and clinical utility of the concept
Sabine C. Linn et al.
EUROPEAN JOURNAL OF CANCER (2009)
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
Zachary T. Schafer et al.
NATURE (2009)
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
Maximina H. Yun et al.
NATURE (2009)
Mechanisms of change in gene copy number
P. J. Hastings et al.
NATURE REVIEWS GENETICS (2009)
p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo
Manran Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Regulation of Mammary Stem/Progenitor Cells by PTEN/Akt/β-Catenin Signaling
Hasan Korkaya et al.
PLOS BIOLOGY (2009)
Facilitating replication under stress: an oncogenic function of MYC?
Steffi Herold et al.
NATURE REVIEWS CANCER (2009)
Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients
Bahriye Aktas et al.
BREAST CANCER RESEARCH (2009)
AKT1 Inhibits Homologous Recombination by Inducing Cytoplasmic Retention of BRCA1 and RAD51
Isabelle Plo et al.
CANCER RESEARCH (2008)
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer
Mei Zhang et al.
CANCER RESEARCH (2008)
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
Jing Yang et al.
DEVELOPMENTAL CELL (2008)
A sensitive test for the detection of specific DSB repair defects in primary cells from breast cancer specimens
Marlen Keimling et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
BRCA1 regulates human mammary stem/progenitor cell fate
Suling Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The ubiquitin E3 ligase activity of BRCA1 and its biological functions
Wenwen Wu et al.
Cell Division (2008)
Essential role for nuclear PTEN in maintaining chromosomal integrity
Wen Hong Shen et al.
CELL (2007)
Mutations of TGF beta signaling molecules in human disease
Kelly A. Harradine et al.
ANNALS OF MEDICINE (2006)
The pleiotropic roles of transforming growth factor beta in homeostasis and carcinogenesis of endocrine organs
Markus C. Fleisch et al.
ENDOCRINE-RELATED CANCER (2006)
p53 in recombination and repair
S. A. Gatz et al.
CELL DEATH AND DIFFERENTIATION (2006)
Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer
JA Schardt et al.
CANCER CELL (2005)
TGFß1/Smad3 counteracts BRCA1-dependent repair of DNA damage
A Dubrovska et al.
ONCOGENE (2005)
Glycogen synthase kinase-3 is an endogenous inhibitor of snail transcription: implications for the epithelial-mesenchymal transition
RE Bachelder et al.
JOURNAL OF CELL BIOLOGY (2005)
Altered DNA polymerase ι expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis
J Yang et al.
CANCER RESEARCH (2004)
HER-2 gene amplification can be acquired as breast cancer progresses
SD Meng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
P53′s double life:: transactivation-independent repression of homologous recombination
P Bertrand et al.
TRENDS IN GENETICS (2004)
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial-mesenchymal transition
BHP Zhou et al.
NATURE CELL BIOLOGY (2004)
Hallmarks of 'BRCAness' in sporadic cancers
N Turner et al.
NATURE REVIEWS CANCER (2004)
Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma
WD Foulkes et al.
CANCER (2003)
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
PM Siegel et al.
NATURE REVIEWS CANCER (2003)
Host microenvironment in breast cancer development - Epithelial-mesenchymal transition in breast cancer development
A Vincent-Salomon et al.
BREAST CANCER RESEARCH (2003)
Loss of p53 and centrosome hyperamplification
P Tarapore et al.
ONCOGENE (2002)
Repair of endogenous DNA damage
T Lindahl et al.
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (2000)
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