4.6 Review

The Landscape of PDK1 in Breast Cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Heterogeneity of Circulating Tumor Cells in Breast Cancer: Identifying Metastatic Seeds

Maxim E. Menyailo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Oncology

Behavior of metastatic breast cancer according to subtype

Margot Van Mechelen et al.

BREAST CANCER RESEARCH AND TREATMENT (2020)

Review Oncology

Regulation of breast cancer metastasis signaling by miRNAs

Belinda J. Petri et al.

CANCER AND METASTASIS REVIEWS (2020)

Review Chemistry, Medicinal

A patent update on PDK1 inhibitors (2015-present)

Simona Sestito et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2019)

Article Medicine, General & Internal

MiR-873/PD-L1 axis regulates the stemness of breast cancer cells

Lanlan Gao et al.

EBIOMEDICINE (2019)

Review Cell Biology

Metastasis Organotropism: Redefining the Congenial Soil

Yang Gao et al.

DEVELOPMENTAL CELL (2019)

Review Biochemistry & Molecular Biology

The Role of Exosomal MicroRNAs in the Tumor Microenvironment of Breast Cancer

Qingqing Liu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Biochemistry & Molecular Biology

The Regulatory Role of MicroRNAs in Breast Cancer

Hui-Yi Loh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Cell Biology

MicroRNAs Contribute to Breast Cancer Invasiveness

Ivana Fridrichova et al.

Review Oncology

Breast cancer lung metastasis: Molecular biology and therapeutic implications

Liting Jin et al.

CANCER BIOLOGY & THERAPY (2018)

Article Multidisciplinary Sciences

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A

Kyoko Hashimoto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Editorial Material Oncology

AGC kinases in cancer metastasis, immune checkpoint regulation and drug resistance

Gongda Xue et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Oncology

PDK1: At the crossroad of cancer signaling pathways

Paolo Armando Gagliardi et al.

SEMINARS IN CANCER BIOLOGY (2018)

Article Multidisciplinary Sciences

Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer

Jingyi Liu et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

PDK1 promotes tumor growth and metastasis in a spontaneous breast cancer model

J. Du et al.

ONCOGENE (2016)

Article Multidisciplinary Sciences

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

Claudio Raimondi et al.

SCIENTIFIC REPORTS (2016)

Review Oncology

Targeting metastasis

Patricia S. Steeg

NATURE REVIEWS CANCER (2016)

Review Pharmacology & Pharmacy

Cancer metastases: challenges and opportunities

Xiangming Guan

ACTA PHARMACEUTICA SINICA B (2015)

Letter Pathology

Immunohistochemical analysis of PDK1 expression in breast cancer

Ruza Arsenic

DIAGNOSTIC PATHOLOGY (2014)

Article Pharmacology & Pharmacy

The phosphoinositide-dependent protein kinase 1 inhibitor, UCN-01, induces fragmentation: Possible role of metalloproteinases

Rocio Alcantara-Hernandez et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2014)

Article Cell Biology

PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction

Paolo Armando Gagliardi et al.

JOURNAL OF CELL BIOLOGY (2014)

Article Medicine, Research & Experimental

miR-200-containing extracellular vesicles promote breast cancer cell metastasis

Minh T. N. Le et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Biochemistry & Molecular Biology

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors

Eeva M. Sommer et al.

BIOCHEMICAL JOURNAL (2013)

Article Cell Biology

A novel regulatory mechanism links PLCγ1 to PDK1

Claudio Raimondi et al.

JOURNAL OF CELL SCIENCE (2012)

Article Medicine, Research & Experimental

Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models

Cynthia X. Ma et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Biochemistry & Molecular Biology

Proliferative and Antiapoptotic Signaling Stimulated by Nuclear-Localized PDK1 Results in Oncogenesis

Chintan K. Kikani et al.

SCIENCE SIGNALING (2012)

Review Pharmacology & Pharmacy

PDK1 inhibitors

Elisa Barile et al.

PHARMACEUTICAL PATENT ANALYST (2012)

Review Biochemistry & Molecular Biology

Perspectives in PDK1 evolution Insights from photosynthetic and non-photosynthetic organisms

Anna C. Nelson Dittrich et al.

PLANT SIGNALING & BEHAVIOR (2012)

Article Biochemistry & Molecular Biology

Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1

Ayaz Najafov et al.

BIOCHEMICAL JOURNAL (2011)

Article Biochemistry & Molecular Biology

Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR

Kumiko Nagashima et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Cell Biology

Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation

Hideki Yamaguchi et al.

JOURNAL OF CELL BIOLOGY (2011)

Review Cell Biology

The nuts and bolts of AGC protein kinases

Laura R. Pearce et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization

Elizabeth Iorns et al.

BIOCHEMICAL JOURNAL (2009)

Article Cell Biology

PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE

Sophie Pinner et al.

NATURE CELL BIOLOGY (2008)

Review Genetics & Heredity

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

Witold Filipowicz et al.

NATURE REVIEWS GENETICS (2008)

Article Biochemistry & Molecular Biology

Notch-induced T cell development requires phosphoinositide-dependent kinase 1

April P. Kelly et al.

EMBO JOURNAL (2007)

Article Biochemistry & Molecular Biology

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

Camilla Hauge et al.

EMBO JOURNAL (2007)

Article Biochemistry & Molecular Biology

Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation

MP Scheid et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

DD Sarbassov et al.

SCIENCE (2005)

Review Cell Biology

PDK1, the master regulator of AGC kinase signal transduction

A Mora et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2004)

Review Biochemistry & Molecular Biology

Phosphoinositide-dependent protein kinase 1, a sensor of protein conformation

RM Biondi

TRENDS IN BIOCHEMICAL SCIENCES (2004)

Article Multidisciplinary Sciences

Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1):: A potential regulatory mechanism for PDK-1 function

MA Lim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation

BJ Collins et al.

EMBO JOURNAL (2003)

Article Biochemistry & Molecular Biology

Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions

Y Taniyama et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Review Multidisciplinary Sciences

Oncogenic kinase signalling

P Blume-Jensen et al.

NATURE (2001)

Article Biochemistry & Molecular Biology

Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival

P Flynn et al.

CURRENT BIOLOGY (2000)