4.6 Review

FDA-Approved Drugs for Hematological Malignancies-The Last Decade Review

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Polatuzumab Vedotin: a New Target for B Cell Malignancies

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Tafasitamab: First Approval

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Belantamab Mafodotin: First Approval

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Isatuximab for the treatment of relapsed/refractory multiple myeloma

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Hydroxamic acid hybrids as the potential anticancer agents: An Overview

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Review Immunology

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Gilteritinib: First Global Approval

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Review Oncology

Mutant Isocitrate Dehydrogenase Inhibitors as Targeted Cancer Therapeutics

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FDA Approval Summary: Mogamulizumab-kpkc for Mycosis Fungoides and Sezary Syndrome

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CLINICAL CANCER RESEARCH (2019)

Article Pharmacology & Pharmacy

Polatuzumab Vedotin: First Global Approval

Emma D. Deeks

Article Pharmacology & Pharmacy

Selinexor: First Global Approval

Yahiya Y. Syed

Article Pharmacology & Pharmacy

Fedratinib: First Approval

Hannah A. Blair

Article Medicine, General & Internal

Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma

Ajai Chari et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Enasidenib in acute myeloid leukemia: clinical development and perspectives on treatment

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CANCER MANAGEMENT AND RESEARCH (2019)

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An Overview of Monoclonal Antibodies

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Article Pharmacology & Pharmacy

Glasdegib: First Global Approval

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Article Chemistry, Medicinal

Nitro-Group-Containing Drugs

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CAR T Cell Therapy for Hematological Malignancies

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CURRENT MEDICAL SCIENCE (2019)

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Beyond Ruxolitinib: Fedratinib and Other Emergent Treatment Options for Myelofibrosis

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CANCER MANAGEMENT AND RESEARCH (2019)

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The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

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Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead

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Role of TPMT and ITPA variants in mercaptopurine disposition

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CANCER CHEMOTHERAPY AND PHARMACOLOGY (2018)

Review Hematology

Venetoclax: A new wave in hematooncology

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EXPERIMENTAL HEMATOLOGY (2018)

Article Biochemistry & Molecular Biology

Zinc binding groups for histone deacetylase inhibitors

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JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2018)

Article Pharmacology & Pharmacy

Ivosidenib: First Global Approval

Sohita Dhillon

Review Immunology

CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance

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FRONTIERS IN IMMUNOLOGY (2018)

Article Pharmacology & Pharmacy

Moxetumomab Pasudotox: First Global Approval

Sohita Dhillon

Article Pharmacology & Pharmacy

Duvelisib: First Global Approval

Hannah A. Blair

Article Oncology

Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia

Karen Thudium Mueller et al.

CLINICAL CANCER RESEARCH (2018)

Review Hematology

The role of enasidenib in the treatment of mutant IDH2 acute myeloid leukemia

Iman Abou Dalle et al.

THERAPEUTIC ADVANCES IN HEMATOLOGY (2018)

Review Biochemistry & Molecular Biology

BCL-2 family proteins: changing partners in the dance towards death

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CELL DEATH AND DIFFERENTIATION (2018)

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Acalabrutinib: First Global Approval

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Review Oncology

The role of B cell antigen receptors in mantle cell lymphoma

Michael Fichtner et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)

Review Oncology

Gemtuzumab ozogamicin in acute myeloid leukemia

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Article Medicine, General & Internal

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

R. M. Stone et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Pharmacology & Pharmacy

Copanlisib: First Global Approval

Anthony Markham

Article Pharmacology & Pharmacy

Enasidenib: First Global Approval

Esther S. Kim

Article Pharmacology & Pharmacy

Inotuzumab Ozogamicin: First Global Approval

Yvette N. Lamb

Article Pharmacology & Pharmacy

Midostaurin: First Global Approval

Esther S. Kim

Review Medical Laboratory Technology

Programmed Death Ligand-1 (PD-L1) Expression in the Programmed Death Receptor-1 (PD-1)/PD-L1 Blockade A Key Player Against Various Cancers

Jian Guan et al.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE (2017)

Review Biochemistry & Molecular Biology

Structural Chemistry of Human RNA Methyltransferases

Matthieu Schapira

ACS CHEMICAL BIOLOGY (2016)

Article Oncology

Isocitrate dehydrogenase mutations in gliomas

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NEURO-ONCOLOGY (2016)

Review Oncology

A review of blinatumomab, a novel immunotherapy

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JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2016)

Review Biochemistry & Molecular Biology

The recognition of ubiquitinated proteins by the proteasome

Guinevere L. Grice et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Article Pharmacology & Pharmacy

Elotuzumab: First Global Approval

Anthony Markham

Article Pharmacology & Pharmacy

Venetoclax: First Global Approval

Emma D. Deeks

Article Pharmacology & Pharmacy

Daratumumab: First Global Approval

Kate McKeage

Article Pharmacology & Pharmacy

Ixazomib: First Global Approval

Matt Shirley

Article Cell Biology

Multifunctional Abl kinases in health and disease

Aaditya Khatri et al.

JOURNAL OF CELL SCIENCE (2016)

Article Medicine, General & Internal

Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis

Jason Gotlib et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Medicine, General & Internal

Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia

John C. Byrd et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Review Chemistry, Medicinal

Spotlight on ixazomib: potential in the treatment of multiple myeloma

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DRUG DESIGN DEVELOPMENT AND THERAPY (2016)

Review Hematology

Elotuzumab: the first approved monoclonal antibody for multiple myeloma treatment

Hila Magen et al.

THERAPEUTIC ADVANCES IN HEMATOLOGY (2016)

Article Oncology

Panobinostat for the Treatment of Multiple Myeloma

Jacob P. Laubach et al.

CLINICAL CANCER RESEARCH (2015)

Article Pharmacology & Pharmacy

Blinatumomab: First Global Approval

Mark Sanford

Article Pharmacology & Pharmacy

Panobinostat: First Global Approval

Karly P. Garnock-Jones

Article Pharmacology & Pharmacy

Ixazomib for the treatment of multiple myeloma

Massimo Gentile et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2015)

Review Biochemistry & Molecular Biology

Preclinical and clinical development of inotuzumab-ozogamicin in hematological malignancies

Boris Shor et al.

MOLECULAR IMMUNOLOGY (2015)

Article Medicine, General & Internal

Ruxolitinib versus Standard Therapy for the Treatment of Polycythemia Vera

Alessandro M. Vannucchi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

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Ponatinib: Accelerated Disapproval

Justin F. Gainor et al.

ONCOLOGIST (2015)

Review Oncology

New dimension in therapeutic targeting of BCL-2 family proteins

Samaher Besbes et al.

ONCOTARGET (2015)

Review Pharmacology & Pharmacy

Orphan drug approvals of 2014: Europe and the United States

Peter Norman

EXPERT OPINION ON ORPHAN DRUGS (2015)

Article Pharmacology & Pharmacy

Development of asparaginase Erwinia chrysanthemi for the treatment of acute lymphoblastic leukemia

Wanda L. Salzer et al.

PHARMACEUTICAL SCIENCE TO IMPROVE THE HUMAN CONDITION: WINNERS AND FINALISTS FOR THE PRIX GALIEN USA AWARDS 2013 (2014)

Article Pharmacology & Pharmacy

Obinutuzumab: First Global Approval

Fiona Cameron et al.

Article Pharmacology & Pharmacy

Ibrutinib: First Global Approval

Fiona Cameron et al.

Article Pharmacology & Pharmacy

Idelalisib: First Global Approval

Anthony Markham

Article Pharmacology & Pharmacy

Pembrolizumab: First Global Approval

Raewyn M. Poole

Article Pharmacology & Pharmacy

Belinostat: First Global Approval

Raewyn M. Poole

Review Biotechnology & Applied Microbiology

Omacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia

Yaoyu Chen et al.

ONCOTARGETS AND THERAPY (2014)

Article Multidisciplinary Sciences

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

Chong Wang et al.

NATURE COMMUNICATIONS (2014)

Article Pharmacology & Pharmacy

Pomalidomide: First Global Approval

Shelley Elkinson et al.

Letter Hematology

CD30 expression in peripheral T-cell lymphomas

Elena Sabattini et al.

HAEMATOLOGICA (2013)

Review Nanoscience & Nanotechnology

Treating relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia: liposome-encapsulated vincristine

Tyler Davis et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2013)

Review Chemistry, Medicinal

The Utility of Modeling and Simulation in Drug Development and Regulatory Review

Shiew-Mei Huang et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2013)

Review Oncology

Pomalidomide: the new immunomodulatory agent for the treatment of multiple myeloma

A. A. Chanan-Khan et al.

BLOOD CANCER JOURNAL (2013)

Article Pharmacology & Pharmacy

A Step Toward More Accurate Dosing for Mercaptopurine in Childhood Acute Lymphoblastic Leukemia

Hussain Mulla et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2012)

Article Medicine, General & Internal

Ponatinib in Refractory Philadelphia Chromosome-Positive Leukemias

Jorge E. Cortes et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Medicine, General & Internal

A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis

Srdan Verstovsek et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Medicine, General & Internal

JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis

Claire Harrison et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Oncology

Antibody Fusion Proteins: Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox

Robert J. Kreitman et al.

CLINICAL CANCER RESEARCH (2011)

Article Pharmacology & Pharmacy

Omacetaxine mepesuccinate for the treatment of leukemia

Theo Daniel Kim et al.

EXPERT OPINION ON PHARMACOTHERAPY (2011)

Editorial Material Biotechnology & Applied Microbiology

Doxorubicin pathways: pharmacodynamics and adverse effects

Caroline F. Thorn et al.

PHARMACOGENETICS AND GENOMICS (2011)

Review Chemistry, Analytical

Analysis of anticancer drugs: A review

Susanne Nussbaumer et al.

TALANTA (2011)

Article Chemistry, Medicinal

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

Fraser F. Fleming et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Medicine, General & Internal

Brentuximab Vedotin (SGN-35) for Relapsed CD30-Positive Lymphomas.

Anas Younes et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Biochemistry & Molecular Biology

Cancer-associated IDH mutations: biomarker and therapeutic opportunities

K. E. Yen et al.

ONCOGENE (2010)

Review Dermatology

Cutaneous T-Cell Lymphoma: Roles for Chemokines and Chemokine Receptors

Xue-Song Wu et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)

Review Multidisciplinary Sciences

The proteasome: Overview of structure and functions

Keiji Tanaka

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2009)

Review Pharmacology & Pharmacy

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

Suzie J. Scales et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2009)

Review Chemistry, Medicinal

Recent Advances in the Development of Multi-Kinase Inhibitors

Martin Krug et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)

Article Oncology

A pilot pharmacokinetic study of oral azacitidine

G. Garcia-Manero et al.

LEUKEMIA (2008)

Review Oncology

Decitabine and its role in the treatment of hematopoietic malignancies

Elizabeth R. Plimack et al.

LEUKEMIA & LYMPHOMA (2007)

Review Pharmacology & Pharmacy

Phosphatidylinositol 3-kinase (PI3K) inhibitors as anticancer drugs

Jeroen C. Verheijen et al.

DRUGS OF THE FUTURE (2007)

Review Biotechnology & Applied Microbiology

Anticancer activities of histone deacetylase inhibitors

Jessica E. Bolden et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Review Medicine, General & Internal

Tyrosine kinases as targets for cancer therapy

DS Krause et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Review Medical Laboratory Technology

Tyrosine kinase inhibitors in cancer therapy

S Madhusudan et al.

CLINICAL BIOCHEMISTRY (2004)

Article Immunology

Mouse CD20 expression and function

J Uchida et al.

INTERNATIONAL IMMUNOLOGY (2004)

Review Oncology

Thalidomide and immunomodulatory drugs as cancer therapy

N Raje et al.

CURRENT OPINION IN ONCOLOGY (2002)

Review Biochemistry & Molecular Biology

Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex

M Orlowski et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)

Review Immunology

Immunotherapeutic perspective for bispecific antibodies

AB van Spriel et al.

IMMUNOLOGY TODAY (2000)