4.6 Article

Evaluation of Comprehensive Gene Expression and NK Cell-Mediated Killing in Glioblastoma Cell Line-Derived Spheroids

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

NK cell-based cancer immunotherapy: from basic biology to clinical development

Sizhe Liu et al.

Summary: NK cells, as a specialized immune effector cell type, play a critical role in immune activation against abnormal cells. Unlike T cell activation, NK cell activation is governed by interactions between NK receptors and target cells, leading to significant attention in cancer immunotherapy. Many efforts are focused on developing and engineering NK cell-based cancer immunotherapy.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

Article Medicine, Research & Experimental

Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells

Hila Shaim et al.

Summary: Glioblastoma stem cells (GSCs) in the aggressive brain cancer Glioblastoma multiforme (GBM) evade immune responses by impairing the function of tumor-infiltrating NK cells through a direct cell-to-cell contact mechanism mediated by alpha v integrin and TGF-β activation. Treatment with inhibitors of integrin or TGF-β signaling, or with TGFBR2 gene-edited allogeneic NK cells, prevents GSC-induced NK cell dysfunction and tumor growth, suggesting a potential therapeutic strategy for GBM.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Review Biochemistry & Molecular Biology

The Role of Selected Chemokines and Their Receptors in the Development of Gliomas

Magdalena Groblewska et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Immunology

The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies

Florent Petitprez et al.

FRONTIERS IN IMMUNOLOGY (2020)

Editorial Material Multidisciplinary Sciences

Vascular regulation of antitumor immunity

Lance L. Munn et al.

SCIENCE (2019)

Article Anatomy & Morphology

A 3D tumor spheroid model for the T98G Glioblastoma cell line phenotypic characterization

Mariam-Eleni Oraiopoulou et al.

TISSUE & CELL (2019)

Review Oncology

Tumor immunotherapy: New aspects of natural killer cells

Yangxi Li et al.

CHINESE JOURNAL OF CANCER RESEARCH (2018)

Review Cell Biology

Molecular insight into targeting the NK cell immune response to cancer

Jai Rautela et al.

IMMUNOLOGY AND CELL BIOLOGY (2018)

Article Oncology

The Microenvironmental Landscape of Brain Tumors

Daniela F. Quail et al.

CANCER CELL (2017)

Review Biotechnology & Applied Microbiology

3D tumor spheroids: an overview on the tools and techniques used for their analysis

Elisabete C. Costa et al.

BIOTECHNOLOGY ADVANCES (2016)

Article Medicine, Research & Experimental

MicroRNA-29b mediates altered innate immune development in acute leukemia

Bethany L. Mundy-Bosse et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Multidisciplinary Sciences

Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages

Teresa E. Peterson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Biochemistry & Molecular Biology

Pathophysiological mechanisms regulated by cytokines in gliomas

Anthos Christofides et al.

CYTOKINE (2015)

Article Medicine, Research & Experimental

Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer

Naoyuki Sakamoto et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2015)

Article Oncology

Spherical Cancer Models in Tumor Biology

Louis-Bastien Weiswald et al.

NEOPLASIA (2015)

Review Immunology

Effect of tumor cells and tumor microenvironment on NK-cell function

Massimo Vitale et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2014)

Review Immunology

Microglia and Macrophages in Malignant Gliomas: Recent Discoveries and Implications for Promising Therapies

Anna Carolina Carvalho da Fonseca et al.

CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2013)

Review Immunology

Oncology Meets Immunology: The Cancer-Immunity Cycle

Daniel S. Chen et al.

IMMUNITY (2013)

Article Multidisciplinary Sciences

Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression

Kate Lawrenson et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2012)

Review Oncology

The blockade of immune checkpoints in cancer immunotherapy

Drew M. Pardoll

NATURE REVIEWS CANCER (2012)

Article Genetics & Heredity

U87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line

Michael James Clark et al.

PLOS GENETICS (2010)

Article Immunology

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

Nicholas D. Huntington et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

Article Biochemical Research Methods

Spheroid-based drug screen: considerations and practical approach

Juergen Friedrich et al.

NATURE PROTOCOLS (2009)

Review Immunology

Up on the tightrope: natural killer cell activation and inhibition

Lewis L. Lanier

NATURE IMMUNOLOGY (2008)

Review Immunology

Functions of natural killer cells

Eric Vivier et al.

NATURE IMMUNOLOGY (2008)

Article Medicine, General & Internal

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

R Stupp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Mathematical & Computational Biology

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

RA Irizarry et al.

BIOSTATISTICS (2003)

Article Biochemical Research Methods

Analysis of high density expression microarrays with signed-rank call algorithms

WM Liu et al.

BIOINFORMATICS (2002)

Article Biochemistry & Molecular Biology

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

R Edgar et al.

NUCLEIC ACIDS RESEARCH (2002)

Review Multidisciplinary Sciences

Stem cells, cancer, and cancer stem cells

T Reya et al.

NATURE (2001)

Article Clinical Neurology

The development of necrosis and apoptosis in glioma: experimental findings using spheroid culture systems

HS Bell et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2001)