相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma
Kirit Singh et al.
CLINICAL CANCER RESEARCH (2022)
Pericytes regulate vascular immune homeostasis in the CNS
Orsolya Toeroek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood-brain barrier
Mariana Castro Dias et al.
JOURNAL OF CELL SCIENCE (2021)
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling
Xiao-Ning Zhang et al.
CELL RESEARCH (2021)
CCL19 enhances CD8+ T-cell responses and accelerates HBV clearance
Yan Yan et al.
JOURNAL OF GASTROENTEROLOGY (2021)
Integrin cross-talk modulates stiffness-independent motility of CD4+T lymphocytes
Sarah Hyun Ji Kim et al.
MOLECULAR BIOLOGY OF THE CELL (2021)
Cellular model system to dissect the isoform-selectivity of Akt inhibitors
Lena Quambusch et al.
NATURE COMMUNICATIONS (2021)
Active surveillance characterizes human intratumoral T cell exhaustion
Ran You et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Adhesion of T Cells to Endothelial Cells Facilitates Blinatumomab-Associated Neurologic Adverse Events
Matthias Klinger et al.
CANCER RESEARCH (2020)
Meningeal lymphatic vessels regulate brain tumor drainage and immunity
Xueting Hu et al.
CELL RESEARCH (2020)
VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours
Eric Song et al.
NATURE (2020)
High-resolution tomographic analysis of in vitro 3D glioblastoma tumor model under long-term drug treatment
Mehmet S. Ozturk et al.
SCIENCE ADVANCES (2020)
Immune-related Encephalitis in Two Patients Treated With Immune Checkpoint Inhibitor
Lucie Robert et al.
CLINICAL LUNG CANCER (2020)
The endothelial basement membrane acts as a checkpoint for entry of pathogenic T cells into the brain
Xueli Zhang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy
Aaron R. Lim et al.
ELIFE (2020)
CXCR3 Ligands in Cancer and Autoimmunity, Chemoattraction of Effector T Cells, and Beyond
Nathan Karin
FRONTIERS IN IMMUNOLOGY (2020)
Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma The CheckMate 143 Phase 3 Randomized Clinical Trial
David A. Reardon et al.
JAMA ONCOLOGY (2020)
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier
Judith Hauptmann et al.
ACTA NEUROPATHOLOGICA (2020)
Targeting CCL20 inhibits subarachnoid hemorrhage-related neuroinflammation in mice
Li-Shang Liao et al.
Aging-US (2020)
PD-1 Inhibitors: Do they have a Future in the Treatment of Glioblastoma?
Mustafa Khasraw et al.
CLINICAL CANCER RESEARCH (2020)
EGFR/Ras-induced CCL20 production modulates the tumour microenvironment
Andreas Hippe et al.
BRITISH JOURNAL OF CANCER (2020)
Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects
Chunxiao Li et al.
MOLECULAR CANCER (2020)
Nivolumab-induced seronegative encephalitis
Goncalo Cabral et al.
JOURNAL OF NEUROIMMUNOLOGY (2020)
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy
Soniya Bastola et al.
NATURE COMMUNICATIONS (2020)
Comparing CAR T-cell toxicity grading systems: application of the ASTCT grading system and implications for management
Martina Pennisi et al.
BLOOD ADVANCES (2020)
Metabolic coordination of T cell quiescence and activation
Nicole M. Chapman et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Targeting the Warburg effect for cancer treatment: Ketogenic diets for Check for management of glioma
Angela Poff et al.
SEMINARS IN CANCER BIOLOGY (2019)
Perivascular signals alter global gene expression profile of glioblastoma and response to temozolomide in a gelatin hydrogel
Mai T. Ngo et al.
BIOMATERIALS (2019)
CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury
Mary T. Joy et al.
CELL (2019)
Brain Tumor Microenvironment and Host State: Implications for Immunotherapy
William Tomaszewski et al.
CLINICAL CANCER RESEARCH (2019)
Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma
Timothy F. Cloughesy et al.
NATURE MEDICINE (2019)
A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine
Simon Plummer et al.
SCIENTIFIC REPORTS (2019)
CAR T cells for brain tumors: Lessons learned and road ahead
David Akhavan et al.
IMMUNOLOGICAL REVIEWS (2019)
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
Angeliki M. Nikolakopoulou et al.
NATURE NEUROSCIENCE (2019)
PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
Isabella Wimmer et al.
FRONTIERS IN IMMUNOLOGY (2019)
Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study
Georgina Long et al.
LANCET ONCOLOGY (2019)
Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection
Marie Wiatr et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Engineering of human brain organoids with a functional vascular-like system
Bilal Cakir et al.
NATURE METHODS (2019)
Multiple nivolumab-induced CNS demyelination with spontaneous resolution in an asymptomatic metastatic melanoma patient
Vincent Pillonel et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Clinical heterogeneity of hypophysitis secondary to PD-1/PD-L1 blockade: insights from four cases
Isabella Lupi et al.
ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS (2019)
Claudin-5: gatekeeper of neurological function
Chris Greene et al.
FLUIDS AND BARRIERS OF THE CNS (2019)
Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation
Sarah Mundt et al.
SCIENCE IMMUNOLOGY (2019)
Chimeric antigen receptor T-cell therapy - assessment and management of toxicities
Sattva S. Neelapu et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data
Jann N. Sarkaria et al.
NEURO-ONCOLOGY (2018)
Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain
Winfried Neuhaus et al.
BIOMATERIALS (2018)
Neurological Adverse Events Associated with Immune Checkpoint Inhibitors: Diagnosis and Management
Christophoros Astaras et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2018)
Metabolic regulation of leukocyte motility and migration
Federica M. Marelli-Berg et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2018)
Multi-center study finds postoperative residual non-enhancing component of glioblastoma as a new determinant of patient outcome
Aikaterini Kotrotsou et al.
JOURNAL OF NEURO-ONCOLOGY (2018)
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
Margherita Norelli et al.
NATURE MEDICINE (2018)
Generation of human vascularized brain organoids
Missy T. Pham et al.
NEUROREPORT (2018)
CARs versus BiTEs: A Comparison between T Cell-Redirection Strategies for Cancer Treatment
Clare Y. Slaney et al.
CANCER DISCOVERY (2018)
Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma
Tomas Garzon-Muvdi et al.
Oncotarget (2018)
Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System
Mauro P. Avanzi et al.
CELL REPORTS (2018)
Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain
Andree-Anne Berthiaume et al.
CELL REPORTS (2018)
A molecular atlas of cell types and zonation in the brain vasculature
Michael Vanlandewijck et al.
NATURE (2018)
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors
Pakawat Chongsathidkiet et al.
NATURE MEDICINE (2018)
PDGFRβ Cells Rapidly Relay Inflammatory Signal from the Circulatory System to Neurons via Chemokine CCL2
Lihui Duan et al.
NEURON (2018)
Emerging Cellular Therapies for Cancer
Sonia Guedan et al.
Annual Review of Immunology (2018)
Neurological complications of immune checkpoint inhibitors: what happens when you take the brakes off' the immune system
Marinos C. Dalakas
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2018)
Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas
Jennifer E. Kim et al.
CLINICAL CANCER RESEARCH (2017)
Protective and Pathological Immunity during Central Nervous System Infections
Robyn S. Klein et al.
IMMUNITY (2017)
Pembrolizumab-Induced Encephalopathy: A Review of Neurological Toxicities with Immune Checkpoint Inhibitors
Sophie Feng et al.
JOURNAL OF THORACIC ONCOLOGY (2017)
The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases
Annika Sommer et al.
MOLECULAR NEURODEGENERATION (2017)
C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways
Jeffrey S. Smith et al.
MOLECULAR PHARMACOLOGY (2017)
High-dimensional, single-cell characterization of the brain's immune compartment
Ben Korin et al.
NATURE NEUROSCIENCE (2017)
Targeting Neoantigens in Glioblastoma: An Overview of Cancer Immunogenomics and Translational Implications
Tanner M. Johanns et al.
NEUROSURGERY (2017)
Case Report: Encephalitis, with Brainstem Involvement, Following Checkpoint Inhibitor Therapy in Metastatic Melanoma
Simon Bossart et al.
ONCOLOGIST (2017)
Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance
Anne Rogel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells
Juliane Gust et al.
CANCER DISCOVERY (2017)
Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival
Yuan Pan et al.
ONCOTARGET (2017)
Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
Spyros Darmanis et al.
CELL REPORTS (2017)
Caveolin1 Is Required for Th1 Cell Infiltration, but Not Tight Junction Remodeling, at the Blood-Brain Barrier in Autoimmune Neuroinflammation
Sarah E. Lutz et al.
CELL REPORTS (2017)
Metabolic Reprogramming in Glioma
Marie Strickland et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)
Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy
Wenchao Zhou et al.
CELL STEM CELL (2017)
The Microenvironmental Landscape of Brain Tumors
Daniela F. Quail et al.
CANCER CELL (2017)
T cell responses in the central nervous system
Thomas Korn et al.
NATURE REVIEWS IMMUNOLOGY (2017)
The movers and shapers in immune privilege of the CNS
Britta Engelhardt et al.
NATURE IMMUNOLOGY (2017)
Vascular, glial, and lymphatic immune gateways of the central nervous system
Britta Engelhardt et al.
ACTA NEUROPATHOLOGICA (2016)
Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients
Niels Halama et al.
CANCER CELL (2016)
Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment
Jin-Sung Park et al.
CANCER CELL (2016)
CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells
Alan L. Chang et al.
CANCER RESEARCH (2016)
Expansion and Activation of CD103+ Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition
Helene Salmon et al.
IMMUNITY (2016)
The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression
Anna Joy et al.
JOURNAL OF NEURO-ONCOLOGY (2016)
Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles
Debayon Paul et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
Christian Schlaeger et al.
NATURE (2016)
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
Christine E. Brown et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Hypoxia and macrophages promote glioblastoma invasion by the CCL4-CCR5 axis
Ying Wang et al.
ONCOLOGY REPORTS (2016)
Serum stimulation of CCR7 chemotaxis due to coagulation factor XIIa-dependent production of high-molecular-weight kininogen domain 5
Manish P. Ponda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells
Lenka V. Hurton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Understanding the Role of T Cells in CNS Homeostasis
Erik Ellwardt et al.
TRENDS IN IMMUNOLOGY (2016)
Decreased Bioenergetic Health Index in monocytes isolated from the pericardial fluid and blood of post-operative cardiac surgery patients
Philip A. Kramer et al.
BIOSCIENCE REPORTS (2015)
CTL- vs Treg lymphocyte-attracting chemokines, CCL4 and CCL20, are strong reciprocal predictive markers for survival of patients with oesophageal squamous cell carcinoma
J. Y. Liu et al.
BRITISH JOURNAL OF CANCER (2015)
Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin
Guillaume Martin-Blondel et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier
Michael Abadier et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
Christina Twyman-Saint Victor et al.
NATURE (2015)
Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy
Rosa Barreira da Silva et al.
NATURE IMMUNOLOGY (2015)
Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes
Ignazio Caruana et al.
NATURE MEDICINE (2015)
The Blood-Brain Barrier
Richard Daneman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
The Evidence of Glioblastoma Heterogeneity
Akio Soeda et al.
SCIENTIFIC REPORTS (2015)
Lactate Regulates Metabolic and Proinflammatory Circuits in Control of T Cell Migration and Effector Functions
Robert Haas et al.
PLOS BIOLOGY (2015)
Akt1 and-2 inhibition diminishes terminal differentiation and enhances central memory CD8+ T-cell proliferation and survival
Rasha Abu Eid et al.
ONCOIMMUNOLOGY (2015)
Severe relapse in a multiple sclerosis patient associated with ipilimumab treatment of melanoma
Edward J. Gettings et al.
MULTIPLE SCLEROSIS JOURNAL (2015)
Immune Checkpoint Inhibitor Therapy Associated Hypophysitis
Moeber Mahzari et al.
CLINICAL MEDICINE INSIGHTS-ENDOCRINOLOGY AND DIABETES (2015)
JAML mediates monocyte and CD8 T cell migration across the brain endothelium
Jorge Ivan Alvarez et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)
Current concepts in the diagnosis and management of cytokine release syndrome
Daniel W. Lee et al.
BLOOD (2014)
DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation
Carsten Minten et al.
BRAIN (2014)
The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
Andrew N. Macintyre et al.
CELL METABOLISM (2014)
Enhancement of T cell recruitment and infiltration into tumours
C. Oelkrug et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2014)
Ipilimumab treatment associated pituitary hypophysitis: Clinical presentation and imaging diagnosis
Yosef Chodakiewitz et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2014)
Leukocyte Migration into Inflamed Tissues
Sussan Nourshargh et al.
IMMUNITY (2014)
Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond
Christopher S. Garris et al.
IMMUNOLOGY (2014)
CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis (Publication with Expression of Concern. See vol. 128, pg. 1200, 2018) (Publication with Expression of Concern. See vol. 127, pg. 3913, 2017)
Yaniv Zohar et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Maraviroc Reduces the Regulatory T-Cell Frequency in Antiretroviral-Naive HIV-Infected Subjects
Maria Mar Pozo-Balado et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases
Hugo Gonzalez et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Cytotoxic-T-Lymphocyte Antigen 4 Receptor Signaling for Lymphocyte Adhesion Is Mediated by C3G and Rap1
Yoel Kloog et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Mfsd2a is critical for the formation and function of the blood-brain barrier
Ayal Ben-Zvi et al.
NATURE (2014)
Pituitary Expression of CTLA-4 Mediates Hypophysitis Secondary to Administration of CTLA-4 Blocking Antibody
Shintaro Iwama et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity
Liang-Chuan S. Wang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
CNS-specific T cells shape brain function via the choroid plexus
Kuti Baruch et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
LOH in the HLA Class I Region at 6p21 Is Associated with Shorter Survival in Newly Diagnosed Adult Glioblastoma
Jacky T. Yeung et al.
CLINICAL CANCER RESEARCH (2013)
Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level
Justyna Kmiecik et al.
JOURNAL OF NEUROIMMUNOLOGY (2013)
Microenvironmental regulation of tumor progression and metastasis
Daniela F. Quail et al.
NATURE MEDICINE (2013)
Getting Leukocytes to the Site of Inflammation
W. A. Muller
VETERINARY PATHOLOGY (2013)
TGFβ signaling plays a critical role in promoting alternative macrophage activation
Dapeng Gong et al.
BMC IMMUNOLOGY (2012)
T cell trafficking and metabolism: novel mechanisms and targets for immunomodulation
C. Mauro et al.
CURRENT OPINION IN PHARMACOLOGY (2012)
Dipeptidyl peptidase-IV inhibits glioma cell growth independent of its enzymatic activity
Petr Busek et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Mechanism of Clostridium perfringens Enterotoxin Interaction with Claudin-3/-4 Protein Suggests Structural Modifications of the Toxin to Target Specific Claudins
Anna Veshnyakova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth
Eva Schlecker et al.
JOURNAL OF IMMUNOLOGY (2012)
Matrix metalloproteinase-1 expression enhances tumorigenicity as well as tumor-related angiogenesis and is inversely associated with TIMP-4 expression in a model of glioblastoma
Nicholas A. Pullen et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
T cells become licensed in the lung to enter the central nervous system
Francesca Odoardi et al.
NATURE (2012)
Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots
Ziv Shulman et al.
NATURE IMMUNOLOGY (2012)
Expression of FMS-like Tyrosine Kinase 3 Ligand by Oncolytic Herpes Simplex Virus Type I Prolongs Survival in Mice Bearing Established Syngeneic Intracranial Malignant Glioma
Zachary Barnard et al.
NEUROSURGERY (2012)
Capture, crawl, cross: the T cell code to breach the blood-brain barriers
Britta Engelhardt et al.
TRENDS IN IMMUNOLOGY (2012)
Chemokines and the signaling modules regulating integrin affinity
Alessio Montresor et al.
FRONTIERS IN IMMUNOLOGY (2012)
The profile of Th17 subset in glioma
Jinhui Hu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2011)
CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity
Lillian Cruz-Orengo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets
Cliff Y. Yang et al.
NATURE IMMUNOLOGY (2011)
Metabolism, migration and memory in cytotoxic T cells
David Finlay et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Reduced blood brain barrier breakdown in P-selectin deficient mice following transient ischemic stroke: a future therapeutic target for treatment of stroke
Albert Y. Jin et al.
BMC NEUROSCIENCE (2010)
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners
Xinmei Zhu et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2010)
CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease
Romeo Sporici et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function
Laura Rivino et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood-Brain Barrier Endothelium
Oliver Steiner et al.
JOURNAL OF IMMUNOLOGY (2010)
Pericytes regulate the blood-brain barrier
Annika Armulik et al.
NATURE (2010)
Pericytes are required for blood-brain barrier integrity during embryogenesis
Richard Daneman et al.
NATURE (2010)
Breaching multiple barriers: leukocyte motility through venular walls and the interstitium
Sussan Nourshargh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment
Serena Pellegatta et al.
NEURO-ONCOLOGY (2010)
Anti-CTLA-4 antibody therapy associated autoimmune hypophysitis: serious immune related adverse events across a spectrum of cancer subtypes
Troy Dillard et al.
PITUITARY (2010)
Fibroblast growth factor signalling: from development to cancer
Nicholas Turner et al.
NATURE REVIEWS CANCER (2010)
Updated Biological Roles for Matrix Metalloproteinases and New Intracellular Substrates Revealed by Degradomics
Georgina S. Butler et al.
BIOCHEMISTRY (2009)
Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties
Rachel L. Rutishauser et al.
IMMUNITY (2009)
Caveolae-mediated Internalization of Occludin and Claudin-5 during CCL2-induced Tight Junction Remodeling in Brain Endothelial Cells
Svetlana M. Stamatovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Human Regulatory T Cells Are Targets for Human Immunodeficiency Virus (HIV) Infection, and Their Susceptibility Differs Depending on the HIV Type 1 Strain
Maria E. Moreno-Fernandez et al.
JOURNAL OF VIROLOGY (2009)
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
Andrea Reboldi et al.
NATURE IMMUNOLOGY (2009)
A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population.
Alex B. Haynes et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction
Britta Engelhardt et al.
SEMINARS IN IMMUNOPATHOLOGY (2009)
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
John S. Tzartos et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Chemokine production and chemokine receptor expression by human glioma cells: Role of CXCL10 in tumour cell proliferation
Seema V. Maru et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
Perivascular Spaces and the Two Steps to Neuroinflammation
Trevor Owens et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5
Andrea Taddei et al.
NATURE CELL BIOLOGY (2008)
Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: Case study
Amy B. Heimberger et al.
NEURO-ONCOLOGY (2008)
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
Justin T. Jordan et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)
CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions
M. Krumbholz et al.
JOURNAL OF NEUROIMMUNOLOGY (2007)
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma
Antje Wick et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Inflammation directs memory precursor and short-lived effector CD8+ T cell fates via the graded expression of T-bet transcription factor
Nikhil S. Joshi et al.
IMMUNITY (2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells
Martin A. Schneider et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Getting to the site of inflammation: the leukocyte adhesion cascade updated
Klaus Ley et al.
NATURE REVIEWS IMMUNOLOGY (2007)
CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis
Erin E. McCandless et al.
JOURNAL OF IMMUNOLOGY (2006)
Transcriptional regulator Id2 mediates CD8+ T cell immunity
Michael A. Cannarile et al.
NATURE IMMUNOLOGY (2006)
An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme
Abdejabar El Andaloussi et al.
NEURO-ONCOLOGY (2006)
Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis
S Agrawal et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Adoptive transfer of type 1 CTL mediates effective anti-central nervous system tumor response: Critical roles of IFN-inducible protein-10
F Nishimura et al.
CANCER RESEARCH (2006)
Protein kinase Cα-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability
SM Stamatovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood
Y Ziv et al.
NATURE NEUROSCIENCE (2006)
Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domains
J Millán et al.
NATURE CELL BIOLOGY (2006)
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells
J Ikenouchi et al.
JOURNAL OF CELL BIOLOGY (2005)
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
AM Intlekofer et al.
NATURE IMMUNOLOGY (2005)
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
M Greter et al.
NATURE MEDICINE (2005)
Homing phenotypes of tumor-specific CD8 T cells are predetermined at the tumor site by crosspresenting APCs
T Calzascia et al.
IMMUNITY (2005)
Diapedesis of mononuclear cells across cerebral venules during experimental autoimmune encephalomyelitis leaves tight junctions intact
H Wolburg et al.
ACTA NEUROPATHOLOGICA (2005)
Cutting edge:: TGF-β induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
MC Fantini et al.
JOURNAL OF IMMUNOLOGY (2004)
Intratumoral infusion of interleukin-1β and interferon-γ induces tumor invasion with macrophages and lymphocytes in a rat glioma model
S Frewert et al.
NEUROSCIENCE LETTERS (2004)
T cell deficiency leads to cognitive dysfunction: Implications for therapeutic vaccination for schizophrenia and other psychiatric conditions
J Kipnis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
C Uyttenhove et al.
NATURE MEDICINE (2003)
Cutting edge: Cross-presentation as a mechanism for efficient recruitment of tumor-specific CTL to the brain
T Calzascia et al.
JOURNAL OF IMMUNOLOGY (2003)
CD8+ T cells from patients with acute multiple sclerosis display selective increase of adhesiveness in brain venules:: a critical role for P-selectin glycoprotein ligand-1
L Battistini et al.
BLOOD (2003)
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice
T Nitta et al.
JOURNAL OF CELL BIOLOGY (2003)
Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain
CA Murphy et al.
JOURNAL OF IMMUNOLOGY (2002)
Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis
M Sixt et al.
JOURNAL OF CELL BIOLOGY (2001)
Anti-inflammatory cytokines: Expression and action in the brain
L Vitkovic et al.
NEUROIMMUNOMODULATION (2001)
Marimastat: the clinical development of a matrix metalloproteinase inhibitor
AL Thomas et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2000)
Complex phenotype of mice lacking occludin, a component of tight junction strands
M Saitou et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein
K Fujita et al.
FEBS LETTERS (2000)