相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells
Carsten Riether et al.
CELL REPORTS (2021)
Targeting Chronic Myeloid Leukemia Stem/Progenitor Cells Using Venetoclax-Loaded Immunoliposome
Mohammad Houshmand et al.
CANCERS (2021)
Metabolic alterations mediated by STAT3 promotes drug persistence in CML
Sweta B. Patel et al.
LEUKEMIA (2021)
Prospects for achieving treatment-free remission in chronic myeloid leukaemia
Giuseppe Saglio et al.
BRITISH JOURNAL OF HAEMATOLOGY (2020)
CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy
Ross Kinstrie et al.
LEUKEMIA (2020)
Delineation of target expression profiles in CD34+/CD38- and CD34+/CD38+ stem and progenitor cells in AML and CML
Harald Herrmann et al.
BLOOD ADVANCES (2020)
Bone marrow microenvironment: The guardian of leukemia stem cells
Mohammad Houshmand et al.
WORLD JOURNAL OF STEM CELLS (2019)
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting
Niklas Landberg et al.
HAEMATOLOGICA (2018)
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting
Niklas Landberg et al.
HAEMATOLOGICA (2018)
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia
Bin Zhang et al.
NATURE MEDICINE (2018)
PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia
Damian Lai et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Residual Peripheral Blood CD26+ Leukemic Stem Cells in Chronic Myeloid Leukemia Patients During TKI Therapy and During Treatment-Free Remission
Monica Bocchia et al.
FRONTIERS IN ONCOLOGY (2018)
Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses
Jerome Bourgeais et al.
ONCOTARGET (2017)
Expression of CD25 on leukemic stem cells in BCR-ABL1+ CML: Potential diagnostic value and functional implications
Irina Sadovnik et al.
EXPERIMENTAL HEMATOLOGY (2017)
Combined inhibition of beta-catenin and Bcr-Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro and in vivo
H. Zhou et al.
LEUKEMIA (2017)
Bone marrow mesenchymal stromal cell (MSC) gene profiling in chronic myeloid leukemia (CML) patients at diagnosis and in deep molecular response induced by tyrosine kinase inhibitors (TKIs)
Djamel Aggoune et al.
LEUKEMIA RESEARCH (2017)
Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells
H. S. Madapura et al.
ONCOGENE (2017)
CD99 is a therapeutic target on disease stem cells in myeloid malignancies
Stephen S. Chung et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Immature CML cells implement a BMP autocrine loop to escape TKI treatment
Elodie Grockowiak et al.
BLOOD (2017)
Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine
Giulia Cheloni et al.
BLOOD (2017)
Leukotriene signaling via ALOX5 and cysteinyl leukotriene receptor 1 is dispensable for in vitro growth of CD34 +CD38- stem and progenitor cells in chronic myeloid leukemia
Monika Dolinska et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML
Irina Sadovnik et al.
CLINICAL CANCER RESEARCH (2016)
IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome
N. Landberg et al.
LEUKEMIA (2016)
FZD7 regulates BMSCs-mediated protection of CML cells
Na Liu et al.
ONCOTARGET (2016)
ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis
Maria Anna Zipeto et al.
CELL STEM CELL (2016)
Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche
Haobin Ye et al.
CELL STEM CELL (2016)
Chronic myelogenous leukaemia exosomes modulate bone marrow microenvironment through activation of epidermal growth factor receptor
Chiara Corrado et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
The role of Fas-associated phosphatase 1 in leukemia stem cell persistence during tyrosine kinase inhibitor treatment of chronic myeloid leukemia
W. Huang et al.
LEUKEMIA (2016)
Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment
Ann Hanna et al.
MOLECULAR CANCER (2016)
Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition
Mary T. Scott et al.
CANCER DISCOVERY (2016)
Quantitative assessment of the CD26+leukemic stem cell compartment in chronic myeloid leukemia: Patient-subgroups, prognostic impact, and technical aspects
Martin Culen et al.
ONCOTARGET (2016)
The role of MicroRNAs in human cancer
Yong Peng et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2016)
LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential
Christopher S. Hong et al.
CANCER BIOLOGY & THERAPY (2015)
GLI2 inhibition abrogates human leukemia stem cell dormancy
Anil Sadarangani et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Silencing of miR-21 sensitizes CML CD34+ stem/progenitor cells to imatinib-induced apoptosis by blocking PI3K/AKT pathway
Wei-Zhang Wang et al.
LEUKEMIA RESEARCH (2015)
Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists
Stephane Prost et al.
NATURE (2015)
Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations
Elie Traer et al.
BLOOD (2014)
Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia
Harald Herrmann et al.
BLOOD (2014)
The Antiproliferative Activity of Kinase Inhibitors in Chronic Myeloid Leukemia Cells Is Mediated by FOXO Transcription Factors
Francesca Pellicano et al.
STEM CELLS (2014)
Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-β-catenin signaling
Bin Zhang et al.
BLOOD (2013)
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells
Paolo Neviani et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Leukemia cells induce changes in human bone marrow stromal cells
Sara Civini et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2013)
Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status
Michele Cea et al.
LEUKEMIA & LYMPHOMA (2013)
SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells
Z. Wang et al.
ONCOGENE (2013)
PI3K/mTOR pathway inhibitors sensitize chronic myeloid leukemia stem cells to nilotinib and restore the response of progenitors to nilotinib in the presence of stem cell factor
K. Airiau et al.
CELL DEATH & DISEASE (2013)
Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis
Hongfeng Yuan et al.
BLOOD (2012)
HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells
Haojian Zhang et al.
BLOOD (2012)
Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib
Ling Li et al.
CANCER CELL (2012)
Sonic hedgehog maintains survival and growth of chronic myeloid leukemia progenitor cells through β-catenin signaling
Wenxia Su et al.
EXPERIMENTAL HEMATOLOGY (2012)
CD34+/CD38- stem cells in chronic myeloid leukemia express Siglec-3 (CD33) and are responsive to the CD33-targeting drug gemtuzumab/ozogamicin
Harald Herrmann et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2012)
Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib
E. Weisberg et al.
LEUKEMIA (2012)
Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells
Y. Yu et al.
LEUKEMIA (2012)
The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells
Haojian Zhang et al.
NATURE GENETICS (2012)
Mammalian Sirt1: insights on its biological functions
Shahedur Rahman et al.
CELL COMMUNICATION AND SIGNALING (2011)
Janus kinase 2 regulates Bcr-Abl signaling in chronic myeloid leukemia
A. Samanta et al.
LEUKEMIA (2011)
The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis
Alberto M. Martelli et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2010)
TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells
Yoshikane Kikushige et al.
CELL STEM CELL (2010)
PML Nuclear Bodies
Valerie Lallemand-Breitenbach et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
A Brief Review on the Mechanisms of miRNA Regulation
Yimei Cai et al.
GENOMICS PROTEOMICS & BIOINFORMATICS (2010)
CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells
Ravindra Majeti et al.
CELL (2009)
Dipeptidyl Peptidase-4 (CD26): Knowing the Function before Inhibiting the Enzyme
E. Matteucci et al.
CURRENT MEDICINAL CHEMISTRY (2009)
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
Bryan T. MacDonald et al.
DEVELOPMENTAL CELL (2009)
beta-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia
Y. Hu et al.
LEUKEMIA (2009)
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
Chen Zhao et al.
NATURE (2009)
Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia
Yaoyu Chen et al.
NATURE GENETICS (2009)
Expansion of Bcr-Abl-positive leukemic stem cells is dependent on hedgehog pathway activation
Christine Dierks et al.
CANCER CELL (2008)
CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells
Linhua Jin et al.
MOLECULAR CANCER THERAPEUTICS (2008)
PML targeting eradicates quiescent leukaemia-initiating cells
Keisuke Ito et al.
NATURE (2008)
Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo
Chen Zhao et al.
CANCER CELL (2007)
Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies
X. Jiang et al.
LEUKEMIA (2007)
The role of leukotriene receptor signaling in inflammation and cancer
Ramin Massoumi et al.
THESCIENTIFICWORLDJOURNAL (2007)
Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease
W Eisterer et al.
LEUKEMIA (2005)
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
CHM Jamieson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation
SH Xie et al.
ONCOGENE (2001)